For flea or tick infestations, one treatment with Simparica Trio is effective for up to 5 weeks. Further flea or tick treatment should be continued using a different veterinary medicine with a narrower range of action. To prevent lungworm and heartworm disease for one month, a single treatment is required.
How long does Simparica protection last? Simparica is a monthly chewable that starts protecting in hours* and lasts for 35 days. That gives you a little wiggle room at the end of the month, in case you're late with the next month's dose.
Tick Treatment and Control: Treatment with SIMPARICA TRIO can begin at any time of the year. SIMPARICA TRIO should be administered year‑round at monthly intervals or started at least one month before ticks become active.
SIMPARICA TRIO is given orally once a month, at the recommended minimum dose of 0.54 mg/lb (1.2 mg/kg) sarolaner, 0.011 mg/lb (24 μg/kg) moxidectin, and 2.27 mg/lb (5 mg/kg) pyrantel (as pamoate salt). SIMPARICA TRIO can be offered to the dog with or without food.
This small, chewable tablet kills fleas and ticks for up to 35 days to help prevent illnesses in your dog and eliminate and prevent home infestations.
For flea or tick infestations, one treatment with Simparica Trio is effective for up to 5 weeks.
The appropriate strength tablet(s) should be used according to the dog's weight. For treatment of tick and flea infestations Simparica should be given once every month throughout the flea and/or tick season for optimal control. For treatment of sarcoptic mange, Simparica is given monthly for two consecutive months.
Simparica kills adult fleas so fast they don't get a chance to lay eggs and reproduce. Why can I still see fleas on my dog after giving Simparica? Fleas can live in a variety of areas outside of your home as well as on other dogs that your dog may encounter.
The cumulative deaths reported to April 2021 ranged from a high of 2,627 (24%) for fluralaner (Bravecto®) to 726 (2.8%) for afoxolaner (NexGard®) and 412 (12.7%) for sarolaner (Simparica®).
Simparica Trio™ (sarolaner, moxidectin, and pyrantel) Chewables are a safe monthly chewable for dogs that prevents heartworm disease, kills adult fleas and is indicated for the treatment and prevention flea infestations, the treatment and control of tick infestations, and the treatment and control of roundworms and ...
If a dose is missed, give SIMPARICA TRIO immediately and resume monthly dosing. When replacing a monthly heartworm preventive product, SIMPARICA TRIO should be given within one month of the last dose of the former medication.
If you miss a dose of Simparica Trio, give it immediately and resume monthly dosing. Contact your vet if your dog misses a month or more of heartworm prevention—your dog might have become infected with heartworm larvae.
If you forget a month of preventative, make sure to give the next 2 doses on time to "catch up" for that missed month. If you miss several months in a row, you should give your vet a call for advice on when to plan for the next heartworm test and how to get started back on preventatives.
As you can see, both Nexgard and Simparica are extremely good and effective flea and tick treatment and they do not have a major difference between them. But that being said, Simparica does kill an additional tick specie and is relatively faster in eliminating fleas and ticks.
Simparica Trio provides broad protection against some of the biggest threats to dogs including: Adult fleas. Brown Dog Ticks & Paralysis Ticks. Heartworm.
You can give it at any time of the day and you can give it with or without food. After you give your dog his Simparica chew the ingredient sarolaner travels in your dog's blood and quickly reaches tissue fluids just under your dog's skin.
Simparica may cause neurologic signs such as tremors, unsteadiness and/or seizures in dogs with or without a history of neurologic disorders.
Both products are safe for dogs when following directions and have been approved by the FDA to treat and prevent flea and tick infestations. However, unlike Bravecto, Simparica has yet to be approved for use in breeding, pregnant, or lactating dogs.
Both of these drugs already have quite an impressive legacy of suspicion of causing extremely serious adverse reactions, including the death of several hundred of innocent Canine victims.
Simparica may cause neurologic signs such as tremors, unsteadiness and/or seizures in dogs with or without a history of neurologic disorders. Simparica has not been evaluated in pregnant, breeding or lactating dogs. The most common adverse reactions in clinical trials were vomiting and diarrhea.
felis and C. canis, a single oral dose of Simparica Trio™ reduced live flea counts by ≥ 99.9% within 24 hours of treatment and by 100% within 24 hours of weekly re-infestation for 35 days [17].
Simparica protects against more varieties of ticks than Bravecto does and also offers a variation that protects against worms. Bravecto is effective for three times longer (12 weeks), while Simparica must be reapplied monthly. Each medication will require a prescription from your vet.
That same information showed 720 reported seizures for Bravecto in four years and 557 for Simparica in three years. For Credelio, six seizures were reported in the first six months after its approval.
Killing Fleas: Simparica
From the moment your dog ingests Simparica Trio, any fleas they may unknowingly be harboring will be killed in four hours. As for Simparica, any adult fleas who thought they had more time to tie up loose ends will be killed in three hours.
Bravecto is available as a tasty chew for dogs that provides protection from fleas and ticks for 3 months, and a spot-on with 6 months flea and 4 months tick protection.