Blackbeard is set up to be protagonist Monkey D. Luffy's final villain; the fight between these two Yonko's is sure to be an enthralling duel.
Teach, also known as Blackbeard. It is still unclear who will be the final antagonist but as things stand right now, fan theories are more inclined toward Imu being the final antagonist in the series.
Sir Crocodile was the main antagonist of the Alabasta arc of the series and the first Shichibukai that Luffy took down. Crocodile is easily one of the most difficult fights that Luffy has ever fought as he lost to him twice. In fact, Luffy would've died both the times had luck not been on his side.
Charlotte Linlin aka Big Mom is the main antagonist of the Whole Cake Island arc.
The Marine Admiral Aramaki, also known as Ryokugyu (Green Bull), made their debut right after the end of the climatic battle between Luffy and Kaido, trying to hit the Straw Hats and take the head of their captain while they were still recovering.
Against Shanks, even if Luffy possesses weaker Haki, the Devil Fruit abilities of the Hito Hito no Mi, Model: Nika can make up for the deficit and see him emerge victorious. Currently, however, Shanks is likely stronger than Luffy, simply due to the fact that the plot demands that of him.
Usopp remains to be the weakest member of the Straw Hat Pirates. In Wano, the vast majority of the members of the Straw Hat crew received good power-ups. However, Usopp was one of the members who did not receive any power-up and thus is lagging behind.
1 Shirahoshi
Her ability is known to be great enough to destroy the entire world and Luffy is her guide. Her existence alone can bring the entire world to heel and now that she has gained full control over her ability, it goes without saying that she is quite likely the greatest ally that Luffy has so far.
starting with the first kiss shown in one piece it happened during the story of thriller bark where luffy and the straw hats go to thriller bark to defeat moria. and retrieve the shadows that were taken by it during episode 365 absalon takes nami hostage.
Lucci is a member of CP9, a secret agent of the World Government. This group employs deadly martial arts alongside Devil-Fruit powers in a combination that nearly kills all of the Straw Hat Crew. While Luffy manages to fight off Lucci, he would have died without the help of Nico Robin and Usopp.
Dracule Mihawk is Zoro's biggest rival, being the man who holds the title of the World's Strongest Swordsman. Mihawk is extremely skilled with the blade and his swordplay is described as very aesthetic. He is also extremely good at using Haki given that he taught its usage to Zoro.
Enel is a major antagonist in One Piece, being the former "God" of Skypiea and the main antagonist of the Skypiea Arc, as well as a major antagonist of the Sky Island Saga.
Even now, many believe that this final member will be Dr. Vegapunk, who has even asked Luffy directly to let him tag along on their ship. However, based on the most recent chapters of One Piece, it seems more and more likely that the final Straw Hat actually joined the crew long ago.
Luffy will be the strongest character in One Piece by the end of the series. However, the Straw Hat Pirates are far from the only group sailing the Grand Line, meaning they will face a slew of incredibly strong fighters on their quest for the show's titular treasure.
1 Roronoa Zoro
Zoro is the strongest Officer of the Straw Hat Pirates and also the swordsman of the crew.
1 Easiest: Luffy Vs.
Holdem, one of the Headliners of Kaido, was faced by Luffy's wrath during the First Act of the Wano Country arc. Having hurt Tama, Holdem getting beaten up by Luffy was all but certain.
It is evident that the only person capable of surpassing Roger is Luffy. Even though Luffy still has a lot to achieve, he is the only person who can transform the entire world.
Conis and the rest of Skypiea witnessed Luffy completely destabilize Enel's attack. She then witnessed Luffy finally defeat Enel by punching the god straight into the golden bell.
Roger and his men, as seen during the Oden flashback, would simply be too strong for Luffy to defeat in a fight.
Zoro faced off against Kaku, who was also a swordsman with a zoan type devil fruit. It was a laborious fight, but Zoro eventually took the win.