As the final antagonist of the series, Kaguya wielded the deadliest ninjutsu yet. She could create spikes that were able to disintegrate targets, and they were effective against characters even as powerful as Obito.
Madara Uchiha (Japanese: うちは マダラ, Hepburn: Uchiha Madara) is a main antagonist manga and anime character in the Naruto series created by Masashi Kishimoto.
Who is the strongest villain in Naruto and Boruto?
1 Isshiki Otsutsuki Is The Franchise's Strongest Villain
So far, Isshiki Otsutsuki is the strongest being in the entire franchise, as he was able to overpower both Naruto and Sasuke with extreme ease. He was betrayed by Kaguya, but he was able to survive within Jigen, and he was the true leader of Kara.
While there's no denying that Itachi is powerful, Madara is simply stronger, whichever way you look at it. With the powers of the 10 Tails and the Six Paths at his disposal, Madara is miles ahead of Itachi, and there's no way the latter can even put up a fight.
Hashirama Senju, aka the First Hokage, was the only one who could ever beat Madara Uchiha in life. In death and resurrection, Madara gained access to powers he could never gain in life. However, the First Hokage did famously beat Madara in a duel at the Final Valley and seemingly killed Madara.
Arguably the best villain in anime history, Yohan Liebert is the antagonist of Naoki Urasawa's Monster. Yohan's enigma and his ridiculous charisma put him at the very top of the villain rankings. He didn't have any superpowers, only his incredible mind with which he was able to wreak havoc.
The rivalry between Sasuke and Naruto is arguably one of the most popular in the series. They pushed each other to the absolute limits and became some of the strongest characters towards the end of Shippuden.
As an Otsutsuki member, Kaguya is the strongest character in the Narutoverse. However, after consuming the entire Chakra fruit for herself from the God tree, she attained godly feats, making her an unstoppable force in Naruto.
Hidan's primary ability was his inability to die, a result of extensive experimenting with the Jashin religion's various jutsu. His immortality allowed him to survive numerous fatal injuries, and almost any form of dismemberment; he even retained his ability to speak after having his head cut off.
And so we come to the villain you voted as the best of all time. Darth Vader often appears at the top of these lists, as the character has had more of a lasting impact than the blast that took out Alderaan.
Currently, Jigen is the strongest known character in the world of Boruto. His powers were great enough to take on both Naruto Uzumaki and Sasuke Uchiha at the same time. As the fight between the two unraveled, Jigen's superiority over both Naruto and Sasuke became quite apparent.
So, why can Hashirama defeat Kakashi? Well, the first Hokage has one distinct advantage. Yes, Kakashi is able to use all five nature releases, but the wood release that Hashirama can do is a kekkei genkai. It is believed that Hashirama is the only shinobi to ever naturally use the wood release style.
In conclusion, Obito Uchiha would defeat Itachi Uchiha when comparing the two characters in their strongest forms. Obito has one of the strongest, if not the strongest, Sage Mode in the series and has enough chakra reserve to beat Itachi.
