Both Lipitor and Crestor are excellent medications to help improve high cholesterol and to decrease your risk of heart attacks and strokes. In studies, Crestor was more effective at lowering total cholesterol levels and raising HDL levels (Jones, 2003).
Conditions treated: Lipitor and Crestor are both used to treat high cholesterol and reduce certain heart risks. However, Crestor is also used to slow the buildup of plaque in the arteries. (See “Uses of Lipitor vs. Crestor” below.)
Overall, statins are safe as a class of drugs. Serious adverse events are very rare. Among the individual medications, studies have shown that simvastatin (Zocor®) and pravastatin (Pravachol®) seem to be safer and better tolerated than the other statins.
These statins, including atorvastatin (Lipitor®), simvastatin (Zocor®) and fluvastatin (Lescol®), are more likely to cause muscle aches. The hydrophilic statins, including rosuvastatin (Crestor®) and pravastatin (Pravachol®), have to be actively transported and cause fewer muscle aches.
Both Lipitor and Crestor are excellent medications to help improve high cholesterol and to decrease your risk of heart attacks and strokes. In studies, Crestor was more effective at lowering total cholesterol levels and raising HDL levels (Jones, 2003).
Atorvastatin was the safest statin as it resulted in the least number of patients at the end of 2 years of treatment with the new onset of microalbuminuria (10.9%) followed by rosuvastatin (14.3%) and then pravastatin (26.6%). Number of patients with no microalbuminuria at baseline but developed it after 2 years.
March 6, 2023 – For people who don't take common cholesterol medications due to side effects such as muscle aches, a new study suggests taking a drug called bempedoic acid may be more tolerable and still offer sizable protection for their hearts.
Is muscle pain a side effect of all statins? Even though all statins are similar chemically, they have some minor differences that could impact how likely they are to cause muscle pain. Simvastatin is the most likely to cause muscle pain, and fluvastatin is the least likely.
There isn't one best statin to take. No individual statin has been proven to be best at preventing heart attacks and strokes. But there is evidence that rosuvastatin and atorvastatin decrease harmful cholesterol more than other statins.
Yes. Suddenly stopping your statin is dangerous. Data shows that the risk of stroke, heart attack, and death within 4 years of stopping a statin is high.
It's possible, although unlikely, that one particular statin may cause side effects for you while another statin won't. It's thought that simvastatin (Zocor) may be more likely to cause muscle pain as a side effect than other statins when it's taken at high doses.
Our study reported that both 5 mg and 10 mg rosuvastatin significantly decreases blood cholesterol, triglycerides, and LDL levels.
Statins are the most common medicine for high cholesterol. They reduce the amount of cholesterol your body makes.
By Lauran Neergaard • Published March 6, 2023
shows the cholesterol-lowering drug Nexletol made by Esperion Therapeutics Inc. Drugs known as statins are the first-choice treatment for high cholesterol but millions of people who can't or won't take those pills because of side effects may have another option.
Elevated blood sugar levels have been reported with statins, including CRESTOR. The most common side effects may include headache, muscle aches, abdominal pain, weakness, and nausea. Memory loss and confusion have also been reported with statins, including CRESTOR.
One significant difference between atorvastatin and rosuvastatin is their metabolism pathway. Atorvastatin is metabolized extensively in the liver by CYP3A4 – an enzyme that resides in the liver and gastrointestinal tract. CYP3A4 is responsible for the metabolism of numerous medications.
Our present study suggests that switching treatment from 10 mg atorvastatin to 5 mg rosuvastatin may be a useful therapeutic option to reduce sd LDL-C levels in Japanese hypercholesterolemic patients with T2DM with detectable sd LDL-C after long-term atorvastatin treatment.
But among the statins, it's hard to say whether or not one is better than another. Some statins, like rosuvastatin (Crestor), can lower your cholesterol levels more than other statins (if you compare them milligram to milligram). For example, rosuvastatin (Crestor) is considered a moderate-to-high intensity statin.
Specifically, lipophilic statins (those that dissolve more readily in lipids such as oils and fats) may be more effective for preventing liver cancer than hydrophilic statins (those that dissolve more readily in water).