CLEXANE is to be used with extreme caution in patients with a history (more than 100 days) of heparin-induced (including low molecular weight heparins) thrombocytopenia without circulating antibodies.
Clexane should be used with caution in
People over 65 years of age. People who are underweight or overweight. People with decreased kidney function or chronic kidney failure. People with decreased liver function.
Check the patient's most recent lab results, including her complete blood cell and platelet count. Check her medication administration record for previous dose and site. Perform hand hygiene. Prepare the medication and identify the patient according to your facility's guidelines.
Taking Clexane means that your blood takes longer to form clots. This can increase your risk of bleeding. The benefits of using anticoagulants usually outweigh the risks of bleeding and your doctor will consider this before starting treatment. You might bleed or bruise more easily while you are taking Clexane.
Clexane should never be injected into muscle as bleeding into the muscle may occur.
Are there any side effects? Less serious side effects include pain, bruising, bleeding, swelling, itch, or rash at the injection site. Serious side effects include allergic reactions, signs of abnormal bleeding such as prolonged bleeding or bruising easily, nausea, gut pain, or numbness.
Direct subcutaneous injection should be given into a subcutaneous tissue skinfold of the abdomen or the upper-outer aspect of the thigh. The skinfold should be held throughout the injection. After removal of the needle, do not rub the site. Rather, place firm, even pressure to the site of injection for 1-5 minutes.
Monitor signs of anemia, including unusual fatigue, shortness of breath with exertion, bruising, and pale skin. Notify physician or nursing staff immediately if these signs occur.
On subcutaneous administration, the effect can be observed within 20-60 minutes. The effect of Clexane 40 MG Injection lasts for an average duration of 12 hours.
Enoxaparin is contraindicated in patients with active major bleeding, in patients with thrombocytopenia associated with a positive in vitro test for anti-platelet antibody in the presence of enoxaparin sodium, or in patients with hypersensitivity to enoxaparin.
Some people can't take anticoagulants, because they have a higher risk of having a serious problem if bleeding occurs. For example, you may have a higher risk of bleeding if you have uncontrolled high blood pressure, have kidney or liver disease, or drink large amounts of alcohol.
Do not drink cranberry juice, grapefruit juice or pomegranate juice while you're taking warfarin. They can increase the blood-thinning effect of warfarin. You should also seek advice before taking supplements containing vitamin K. The effect of warfarin is also affected by alcohol.
It is safe to inject Clexane® into the abdomen while pregnant. The upper outer side of the thigh • The upper outer part of the buttock (bottom cheek). If you have had surgery (such as a caesarean section), avoid injecting too close to the wound or bandages.
Bleeding is the most common side effect of clexane therapy. You can make the risk of bleeding much smaller by injecting the correct dose of clexane and having blood tests when instructed.
Extensive bruising on the abdomen or site of injection may mean you are not injecting it correctly. Please call your pharmacist or doctor for medical advice if you observe extensive or worsening bruises.
Conduct thorough physical assessment before beginning drug therapy to establish baseline status, determine effectivity of therapy, and evaluate potential adverse effects. Obtain baseline status for complete blood count, fecal occult blood test (FOBT), and clotting studies to determine any potential adverse effects.
Because you are taking a blood thinner, you should try not to hurt yourself and cause bleeding. You need to be careful when you use knives, scissors, razors, or any sharp object that can make you bleed. You also need to avoid activities and sports that could cause injury. Swimming and walking are safe activities.
Stay away from rough sports or other situations where you could be bruised, cut, or injured. Brush and floss your teeth gently. Be careful when using sharp objects, including razors and fingernail clippers. Enoxaparin may cause bleeding problems.
Make sure you take the clexane at the same time every day. If you need to have an injection twice a day then give the first dose in the morning and second dose 12 hours later. Sit or lie in a comfortable position so you are relaxed. Make sure you can see the place you are going to inject.
Performing the injection properly under the skin (called “subcutaneous injection”) will help reduce pain and bruising at the injection site. Clexane Multidose Vial should be injected just under the skin on your stomach, but not too near the belly button or any scar tissue (at least 5cm away from these).
Enoxaparin is usually administered morning and/or at night through an injection underneath the skin (known as a subcutaneous injection). However, for some babies and infants, an indwelling catheter device (Insuflon™) may be used, if appropriate.
The main side effect is that you can bleed too easily, which can cause problems such as: passing blood in your urine. passing blood when you poo or having black poo. severe bruising.
It is important for you to keep having Clexane Multidose Vial injections until your doctor decides to stop them. If you stop, you could get a blood clot which can be very dangerous. If you have any further questions on the use of this medicine, ask your doctor or pharmacist or nurse.
A possible side effect of anticoagulants is excessive bleeding (haemorrhage), because these medicines increase the time it takes for blood clots to form.