Botox was originally intended for people with crossed eyes, and case studies soon followed that showed it also had great benefits for stopping muscle spasms, specifically on the face.
Botox as a Treatment for Cerebral Palsy. Botox was first reported as a treatment for spasticity in children with CP in 1993 (pediatricsdigest.mobi). Spasticity is commonly found in people with CP. According to CerebralPalsy.com, spasticity implies increased muscle tone.
1989 THE FIRST FDA APPROVAL
OnabotulinumtoxinA received FDA approval for therapeutic use in 1989 and was rebranded BOTOX®. Through expanded research into aesthetic uses Allergan later commenced clinical trials to study the treatment's safety and efficacy for moderate to severe frown lines.
Vancouver ophthalmologist Jean Carruthers and her husband, Alastair Carruthers, a dermatologist, pioneered the cosmetic use of botulinum toxin, or Botox, in the late 1980s.
Alan Scott, the doctor credited with developing Botox for medicine, dies at 89 Scott, a California native, was looking to help his patients who had eye disorders and discovered a way for the dangerous chemical to be used in medicine.
The US biological weapons program first produced botulinum toxin during World War II. Because of concerns that Germany had weaponized botulinum toxin, more than 1 million doses of botulinum toxoid vaccine were made for Allied troops preparing to invade Normandy on D-Day.
Botox Cosmetic was innovative for its ability to treat wrinkles, not the elegance with which it did so. Botox was first approved by the FDA for cosmetic use in 2002 for treatment of glabellar lines (“eleven” lines between the brows). Though the same formula as its medical counterpart, it was marketed as Botox Cosmetic.
It was used as early as the 1960s to treat strabismus, or crossed eyes. By the late 1980s, it was FDA-approved and used regularly to treat crossed eyes and eyelid spasms, and its cosmetic advantages were discovered accidentally by an ophthalmologist.
A: Botox is a protein derived from botulinum toxin that can counteract the typical effects of Bell's palsy, which may include weakness and uncoordinated movement of the face; the condition may lead to temporary facial weakness or long-term facial nerve paralysis.
The toxin is called botulinum toxin. It is one of the deadliest toxins known. The bacteria that make this toxin are found naturally in many places, but it's rare for them to make people sick. However, the toxin could be used in a biological attack.
Botox injections work by weakening or paralyzing certain muscles or by blocking certain nerves. The effects last about three to twelve months, depending on what you are treating. The most common side effects are pain, swelling, or bruising at the injection site.
Botox derives from C. botulinum bacteria, which are present in many natural settings, including soil, lakes, forests, and the intestinal tracts of mammals and fish. Naturally occurring C. botulinum bacteria and spores are generally harmless.
The United States produced botulinum toxin during WWII, and designated it "Agent X." More than one million doses of antitoxin were available for allied troops preparing to invade Normandy on D-Day.
If the product was not tested on animals, it is considered to be 'cruelty-free' and this is then classed as truly Vegan. Is Botox vegan? The actual product 'Botulinum Toxin' IS Vegan friendly because it contains nothing of animal origin.
While Botox is made from botulinum toxin, dermal fillers are made from other natural or synthetic materials, including collagen, hyaluronic acid or calcium hydroxylapatite.
Botox has many uses beyond being an effective wrinkle reducer. It has multiple other FDA-approved uses, including chronic migraine prevention, overactive bladder, and hyperhidrosis. It's also being studied for many off-label uses, including depression, male sexual dysfunction, and chronic pelvic pain.
Botox was introduced for treatment of chronic migraine in 2000, after some people receiving injections for cosmetic treatment of facial lines reported improvement of headaches.
If you use Botox for ten or more years, your skin will appear brighter and smoother with fewer wrinkles. Even after stopping Botox injections after years of use, you'll still notice fewer wrinkles between your eyes or on your forehead, which means you'll continue to age gracefully.
Botox treatments are known to have minimal risks, with occasional side-effects that usually go away within 24-48 hours. But some patients may develop side-effects that can last for weeks. These can include droopy eyelids, headaches, neck pain, nausea, etc.
Over time, the Botox components are broken down into harmless particles called amino acids. The broken-down components are excreted from the kidneys as waste, or they're used in other proteins. As such, Botox either leaves your system completely or gets recycled in a harmless form.
Botox injections are usually safe when you're under the care of a licensed and skilled health care provider. The procedure can result in unwanted results or even cause harm if it's given incorrectly. Possible side effects and unwanted results include: Pain, swelling or bruising at the injection site.
BOTOX® Cosmetic contains albumin, a protein component of human blood. The potential risk of spreading viral diseases [eg Creutzfeldt-Jakob Disease (CJD)] via human serum albumin is extremely rare.
In general, Botox lasts 3-4 months. There will certainly be patients in which in lasts longer, in that 4-6 month range, or shorter, in that 2-month range. It is also common for first-timers to notice that it may not last as long initially but may last longer after the second treatment.
Rarely, Botox can affect your heart. It has the potential to cause heart rhythm problems or even heart attacks. This can be more likely if you already have heart problems. Be sure to talk about any heart problems with your healthcare provider before receiving Botox.