Only magnesium L-threonate has been shown to have a high affinity for the brain and have an effect on memory, learning, and cognitive function.
Magnesium L-threonate
Magnesium L-threonate is often used for its potential brain benefits and may help manage certain brain disorders, such as depression and age-related memory loss.
Mauskop recommends 400 milligrams of supplemental magnesium daily (in one dose or split into two doses, taken morning and evening).
Magnesium glycinate is easily absorbed and may have calming properties. It may help reduce anxiety, depression, stress, and insomnia. Yet, scientific evidence on these uses is limited, so more studies are needed ( 8 ). Magnesium glycinate is often used for its calming effects to treat anxiety, depression, and insomnia.
Magnesium's involvement in the mechanics of synaptic transmissions and neuronal plasticity results in its impact on learning and memory. Increased levels of magnesium in the brain have been shown to promote multiple mechanisms of synaptic plasticity that can enhance different forms of learning and memory.
Only magnesium L-threonate has been shown to have a high affinity for the brain and have an effect on memory, learning, and cognitive function.
Having low magnesium levels may negatively affect brain health. Supplementing with magnesium may help reduce certain symptoms of brain fog.
Taking large or frequent doses of dietary magnesium supplements, including magnesium glycinate, can cause adverse effects, including diarrhea, nausea, and stomach cramps. Extremely high intakes of magnesium can lead to an irregular heartbeat and potentially a cardiac arrest, which can be dangerous.
Liquids, powders, or some other forms of this product may contain sugar and/or aspartame. Liquid products may also contain alcohol. Caution is advised if you have diabetes, alcohol dependence, liver disease, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet.
Magnesium deficiency is one of the most common nutrient deficiencies in the world, which is why magnesium supplements can help some people. Benefits of taking magnesium glycinate include helping manage headaches, anxiety, insomnia, cramps and spasms, high blood pressure, and bone loss.
Magnesium glycinate -- Magnesium glycinate (magnesium bound with glycine, a non-essential amino acid) is one of the most bioavailable and absorbable forms of magnesium, and also the least likely to induce diarrhea. It is the safest option for correcting a long-term deficiency.
Most common forms of magnesium including citrate, oxide, chloride, and taurate have been shown to cross the blood-brain barrier and exhibit neuroprotective effects on cognition.
Based on current data, magnesium taurate and glycinate have the most research supporting their effects on anxiety and other mental health disorders. Magnesium malate and threonine have also demonstrated therapeutic effects and may be useful in many psychiatric cases.
As you're probably coming to understand, magnesium is essential for healthy brain and nervous system function; this also includes attention and focus.
Magnesium citrate is a more common choice if you want to maintain magnesium levels for general whole-body health. On the other hand, magnesium glycinate has less bioavailability but can have a calming effect.
Orally, magnesium citrate is the best absorbed form (but it's bonded to a big molecule so there is a smaller amount of magnesium by weight). Mg oxide is the most poorly absorbed form but has the highest Mg per weight, so actually you may get more elemental magnesium out of the same dose of Mg oxide vs.
Therefore, magnesium supplements can be taken at any time of the day, as long as you're able to take them consistently. For some, taking supplements first thing in the morning may be easiest, while others may find that taking them with dinner or just before bed works well for them.
Studies have shown that glycine improves sleep quality, View source and promotes natural, healthy sleep patterns, including healthy REM cycles. Magnesium glycinate is normally included in many over-the-counter magnesium supplements, but always be sure to check, as it is recommended especially for improving sleep.
“Magnesium may help regulate neurotransmitters that are directly related to sleep,” Dr. Umeda says. Neurotransmitters are chemicals that transmit messages between nerve cells in your brain and body. (It's important to note that magnesium plays only a supporting role in their function.)
According to the National Institutes of Health's Office of Dietary Supplements , healthy adult men should generally consume 400 to 420 milligrams (mg) of magnesium daily. Healthy adult women should consume 310 to 320 mg daily. Pregnant women are recommended to consume a higher dose than women who aren't pregnant.
Severe overdoses of magnesium are rare in otherwise healthy people. Getting too much magnesium from the diet is not typically a cause for concern. Occasionally, a high dosage of magnesium from supplements or medications can cause mild symptoms of an overdose, including diarrhea, nausea, and stomach cramps.
Magnesium glycinate is considered safe for most people. As with any supplements, you should consult with your doctor before taking magnesium glycinate, particularly if you are on maintenance medication or have a kidney or heart condition. Buy your supplements only from trusted brands and sources.
Vitamin B9, or folate, is a popular supplement and a key vitamin for supporting brain and neurological health, optimal neurotransmitter function, and balanced psychological health. Another benefit is that it helps encourage cellular detoxification.
Vitamin B2 and vitamin B7 help the nervous system, vitamin B3 and vitamin B6 are required to support neurotransmitters and cellular communication, and vitamin B9 eases mental fatigue. Taking a regular B complex supplement that includes all the necessary B vitamins can help to reduce symptoms of brain fog.