There isn't one single "metabolic syndrome smell," but metabolic issues can cause distinct odors, most famously Trimethylaminuria (TMAU), or "fish odor syndrome," where the body smells like rotten fish due to a buildup of trimethylamine in sweat, urine, and breath. Other conditions, like uncontrolled diabetes (ketones smelling like nail polish) or kidney/liver disease (urine-like or ammonia smell), also create unique metabolic odors.
Trimethylaminuria (TMAU, fish odor syndrome) is an uncommon condition that makes people smell like rotten fish. It's a metabolic disorder. People with TMAU may develop depression and anxiety.
Nonenal® (also known as 2-Nonenal) is a naturally occurring compound responsible for the distinct odor associated with aging. It typically appears after age 40, becoming more noticeable in both men and women.
Trimethylamine has been described as smelling like rotten or decaying fish. As this compound builds up in the body, it causes affected people to give off a strong fishy odor in their sweat, urine, and breath. The intensity of the odor may vary over time.
If you have diabetes, a change in body odor could be a sign of diabetes-related ketoacidosis. High ketone levels cause your blood to become acidic and your body odor to be fruity. In the case of liver or kidney disease, your odor may give off a bleach-like smell due to toxin buildup in your body.
Hydrogen Sulfide. Hydrogen sulfide is a colorless, flammable gas that smells like rotten eggs at low concentration levels in the air. It is commonly known as sewer gas, stink damp, and manure gas. At high concentration levels, it has a sickening sweet odor.
When ketones are present in large quantities they are removed from the body in urine or through exhalation. Ketones can make the dieter's breath smell sweet and fruity BUT if there are large amounts of acetone present it can smell like nail polish remover!
For thousands of years 'fishy' smelling breath and urine have been associated with renal disorders. This smell is now known to be caused by the presence of unusually high concentrations of amines. Some amines are exogenous volatile organic compounds (VOC) that are ingested as part of normal diet.
Trimethylaminuria (TMAU) is a rare disorder in which the body is not able to metabolize the chemical trimethylamine, and this causes body odor.
We get it — it's a common problem, but sometimes it can make you self-conscious (“wait, can other people smell that, too?!”) and affect your confidence. Inner thigh odor is caused by various factors, including excessive sweating, fungal infections, poor hygiene, and hormonal changes.
Salty and sweet flavors tend to weaken first. Later, it may be more difficult to taste things that are bitter or sour. Age can also lessen the sense of smell which is strongest when people are between 30 and 60 years old. Some people eventually lose their sense of smell entirely.
Nonenal production usually starts around the age of 40 and can be exasperated by menopause or other fluctuations in hormones. The frustrating thing about Nonenal is that the smell isn't easily removed, especially from fabrics like shirt collars, sheets, and towels.
Normal vaginal odors
This smell is associated with the good bacteria in your vagina, lactobacilli. Some people describe the odor as yeasty, similar to sourdough bread. A slightly sweet or bittersweet smell, like molasses or gingerbread, may also be a sign that your pH levels have changed.
Without enough B12, your metabolism can slow down, leading to more odor-causing byproducts being released through your sweat. Plus, B12 helps maintain healthy skin, which acts as a barrier to bacteria that cause bad smells. You can find B12 in foods like meat, eggs, and dairy, or through supplements.
Foetor hepaticus is a feature of severe liver disease; a sweet and musty smell both on the breath and in urine. It is caused by the excretion of dimethyl disulphide and methyl mercaptan (CH3SH)2, arising from an excess of methionine.
The menopausal drop in estrogen also leaves our bodies with relatively higher levels of testosterone — produced by our ovaries in small amounts — than before. This can attract more bacteria to sweat, making it smell funkier.
A person with kidney failure may have breath that smells like ammonia or urine. Serious liver disease can make breath smell musty or like garlic and rotten eggs. Compounds that are transported through the blood can also be released through your sweat glands. That can make your armpits and skin smell bad.
Three key signs of Sjögren's syndrome are dry eyes, dry mouth, and profound fatigue, stemming from this autoimmune condition attacking moisture-producing glands, though other symptoms like joint pain, swollen glands, and systemic issues can also occur.
A urine test is used to diagnose trimethylaminuria. The person's urine is tested to look for higher levels of trimethylamine. Testing can be done by giving choline by mouth followed by urine collection a certain number of times over a 24 hour period.
If your kidneys aren't working properly, you may notice one or more of the following signs:
One sign that you possibly have diabetes or high blood sugar is urine that smells sweet or fruity. The sweetness comes from sugar in your urine and is a sign your body is trying to get rid of extra sugar in your blood.
Uremic fetor is a urine-like odor on the breath of people with uremia. The odor occurs from the smell of ammonia, which is created in the saliva as a breakdown product of urea. Uremic fetor is usually associated with an unpleasant metallic taste (dysgeusia) and can be a symptom of chronic kidney disease.
Symptoms of hyperglycaemia
Diabetes: Diabetes is one of the most well-known health conditions linked to changes in body odor. People with uncontrolled diabetes can experience a fruity or acetone-like smell (think nail polish remover) on their breath or skin.
Fetor hepaticus means “fetid liver” or “liver stench”. It's a type of chronic bad breath that's actually a symptom of liver disease. It has a distinctive smell — some say, like rotten eggs and garlic. It's a serious symptom.