A brain abscess is usually caused by infection with either bacteria or fungi. If the immune system is unable to kill an infection, it will try to limit its spread by using healthy tissue to form an abscess, to stop the pus infecting other tissue.
What are the risk factors for cerebral abscess? You have a higher risk of developing this problem if you have heart defects, HIV/AIDS or other conditions that affect your immune system, or if you use medicines that inhibit your immune system.
What Are the Symptoms of a Brain Abscess? The most common symptoms are fever, headache, and nervous system problems. Such problems may be confusion, disorientation, speech or walking difficulties, change in mental status, or arm and leg weakness on one side.
In immunocompetent patients, bacteria are responsible for >95% of brain abscesses, and enter the brain either through contiguous spread following otitis, sinusitis, neurosurgery, or cranial trauma, or through haematogenous dissemination.
Abscess occurs most commonly in the frontal lobe but may occur in any location. Location is closely associated with source. Otogenic abscess occurs almost exclusively in the temporal lobe and cerebellum, while abscess associated with sinus infection is predominantly frontal.
Between 1,500 and 2,500 cases occur each year in the United States. Brain abscesses are most likely to affect adult men aged under 30 years. Among children, they most commonly develop in those aged 4–7 years. Newborns are also at risk.
Prevention. You can reduce the risk of developing a brain abscess by getting treated for infections or health problems that can cause them. Some people, including those with certain heart disorders, may receive antibiotics before dental or other procedures to help reduce the risk of infection.
Outlook (Prognosis)
If untreated, a brain abscess is almost always deadly. With treatment, the death rate is about 10% to 30%. The earlier treatment is received, the better. Some people may have long-term nervous system problems after a brain abscess or surgery.
Most common symptoms
Because these can be symptoms of many illnesses, a brain abscess can be hard to detect at first. In two-thirds of cases, people have symptoms for as long as two weeks before they are diagnosed.
A brain abscess can grow very quickly, typically becoming fully formed within about two weeks. Your doctor will begin treatment immediately after you are diagnosed. Prompt medical attention is the key to relieving your symptoms more quickly and minimizing damage to your long-term health.
Brain abscess passes through 4 stages: early cerebritis, late cerebritis, early capsule, and late capsule. During early cerebritis, nonenhanced CT scans may demonstrate normal findings or may show only poorly marginated subcortical hypodense areas.
For example, in the late stage of bacterial infection, the formation of brain abscess shows MRI manifestation as a typical rim-like enhancement, which is often similar to necrotic malignant tumors, especially glioblastoma multiforme (GBM) (8).
The risk of a brain abscess is a complication of odontogenic infection that is rarely considered by physicians and little spoken of, yet treating dental infections may avoid a potentially life-threatening condition. We report a case of 7-year-old boy with a brain abscess secondary to a dental infection.
The most common route of transmission is through hematogenous spread. Others gain access to the CNS via direct spread from local infectious foci, after head trauma or neurosurgery, or during vaginal delivery from untreated GBS-colonized mothers.
Brain abscesses are focal parenchymal infections, most often occurring in the first two decades of life. Overall, 25% of brain abscesses are seen in children and most often between 4–10 years of age. Abscesses begin as regions of cerebritis and progress to suppurative collections of encapsulated pus within 14 days.
Intracranial abscesses are uncommon, serious, life-threatening infections. They include brain abscess and subdural or extradural empyema and are classified according to the anatomical location or the etiologic agent. The term brain abscess is used in this article to represent all types of intracranial abscesses.
Fungal brain abscess following COVID-19 without contiguous rhino-orbital disease is rare but can occur by haematogenous spread from the lung.
Most patients with brain abscess require surgical drainage, in addition to antibiotics, for both diagnostic and therapeutic purposes.
Complete resolution of abscess with complete recovery of preoperative neuro-deficit was seen in 80.86% cases and recovery with major neuro-deficit was observed in 5.55% cases.
Treat all brain abscesses with antibiotics (usually initially with ceftriaxone or cefotaxime plus metronidazole if clinicians suspect Bacteroides species or plus vancomycin if they suspect S. aureus), typically followed by CT-guided stereotactic aspiration or surgical drainage.
When people first become sick from the virus, they may develop encephalitis — inflammation of the brain — causing confusion, difficulty concentrating, and memory problems. COVID also can trigger the onset of new psychological disorders such as severe depression or anxiety.
Some people who have COVID-19 experience lingering symptoms such as coughing and fatigue, but others also develop nerve pain and brain fog. Brain fog is a non-medical term that encompasses a range of symptoms but can generally be described as decreased ability to focus, as well as feelings of “fuzziness” or confusion.