Alcohol decreases the absorption of dietary thiamine by at least 50 percent and can damage the lining of the intestinal tract, resulting in more malabsorption. Cut out caffeine. Coffee and tea, although less damaging to the intestinal tract, can wreak havoc on thiamine absorption.
The cause of overdose of Vitamin B1 is through overconsumption of Thiamine supplements prescribed for patients with a low level of thiamine, beriberi, neuritis, and digestive and heart diseases. The overdose of thiamine is rare, but its complications are very severe.
Additionally, certain food products such as tea, coffee, raw fish, and shellfish contain thiaminases - enzymes that destroy thiamine.
Certain foods and beverages like tea, shellfish, clams, and raw fish contain thiaminases, or enzymes that deactivate thiamine, but developing a thiamin deficiency due to eating these foods is extremely rare.
Thiamine deficiencies have been attributed to: (1) an inability to absorb available dietary thiamine (often caused by alcoholism or bariatric surgery)15; (2) genetic factors that limit its cellular uptake or processing7; (3) restricted intake of thiamine-containing foods (e.g., white rice-based diets)16; (4) ...
High carbohydrate diets effectively decrease circulating thiamine concentrations by a number of mechanisms.
Brewer's yeast is the food with the highest amount of vitamin B1, with 9.7 mg/100 grams.
So to conclude, it is clear that magnesium is absolutely essential for normal thiamine activity in the body, and one should take great care to ensure sufficient intake when addressing underlying thiamine issues. This is especially important when consistently using high doses.
A diet consisting mainly of white flour, white sugar, and other highly processed carbohydrates can cause thiamin deficiency. At first, people have vague symptoms such as fatigue and irritability, but a severe deficiency (beriberi) can affect the nerves, muscles, heart, and brain.
Thiamine also requires magnesium for absorption from the GI tract [14], activation to its active form (TDP) [15] and for optimal activity of thiamine dependent enzymes within the cell [16, 17].
(Beriberi; Vitamin B1 Deficiency)
At first, people have vague symptoms such as fatigue and irritability, but a severe deficiency (beriberi) can affect the nerves, muscles, heart, and brain. The diagnosis is based on symptoms and a favorable response to thiamin supplements.
Wernicke encephalopathy and Korsakoff syndrome are different conditions that often occur together. Both are due to brain damage caused by a lack of vitamin B1. Lack of vitamin B1 is common in people who have alcohol use disorder. It is also common in people whose bodies do not absorb food properly (malabsorption).
Mental health problems such as memory loss, anxiety, depression, irritability, and insomnia are also associated with deficiencies in vitamin B1. The brain uses this vitamin to help convert glucose or blood sugar into energy. This means that without it, the brain may not have enough energy to function normally.
Several B vitamins aid in the sleep process. Vitamins B1 and B2 not only turn food into energy, but also produce melatonin, the sleep hormone. The production of melatonin shows that these vitamins encourage sleep.
When will I feel better? Taking thiamine will start increasing your body's levels of vitamin B1 within a few hours. However, if you're taking it to treat vitamin B1 deficiency, it may take a few weeks before you start to feel better. It's important to keep taking your thiamine for as long as the doctor tells you to.
If you drink more than three cups of coffee a day, you may need five to 10 times the amount of vitamin B1 than other people. That's largely because you'll excrete more of the nutrient through your kidneys and into your urine.
Early symptoms of thiamin deficiency are vague. They include fatigue, irritability, poor memory, loss of appetite, sleep disturbances, abdominal discomfort, and weight loss. Eventually, a severe thiamin deficiency (beriberi) may develop, characterized by nerve, heart, and brain abnormalities.
Best Form to Take
However, lipid-soluble derivatives of thiamine, such as thiamine propyl disulfide, thiamine tetrahydrofurfuryl disulfide, and benfotiamine, are reported to be more bioavailable than water-soluble thiamine, and have been used to treat diabetic neuropathy, myalgia, and some other conditions.