A bone scan can also be an important tool for detecting cancer that has spread (metastasized) to the bone from the tumor's original location, such as the breast or prostate.
Using a bone scan when cancer is suspected can be particularly helpful because the scan can find both primary cancer—or, cancer that started in your bones—and bone metastases, which is cancer that has spread to the bones from another part of your body.
Bone scans show changes in your bones, but they don't tell you if it's because of cancer or not. You may have to have other tests to figure out what the changes mean. These extra tests will tell you if the spots are cancerous or related to another problem, like arthritis.
Why might I need a bone scan? Bone scans are used primarily to detect the spread of metastatic cancer. Because cancer cells multiply rapidly, they will appear as a hot spot on a bone scan. This is due to the increased bone metabolism and bone repair in the area of the cancer cells.
A bone scan might help determine the cause of unexplained bone pain. The test is sensitive to differences in bone metabolism, which are highlighted in the body by the radioactive tracer. Scanning the whole skeleton helps in diagnosing a wide range of bone disorders, including: Fractures.
Bone cancer can begin in any bone in the body, but it most commonly affects the pelvis or the long bones in the arms and legs. Bone cancer is rare, making up less than 1 percent of all cancers. In fact, noncancerous bone tumors are much more common than cancerous ones.
Bone pain. Pain caused by bone cancer usually begins with a feeling of tenderness in the affected bone. This gradually progresses to a persistent ache or an ache that comes and goes, which continues at night and when resting.
It starts in an early form of bone cells. It most often occurs in young people between the ages of 10 and 30, but about 1 in 10 osteosarcomas develop in people older than 60. It's rare in middle-aged people, and is more common in males than females. These tumors develop most often in bones of the arms, legs, or pelvis.
Blood tests are not needed to diagnose bone cancer, but they may be helpful once a diagnosis is made. For example, high levels of chemicals in the blood such as alkaline phosphatase and lactate dehydrogenase (LDH) can suggest that the cancer may be more advanced.
The results of a bone scan are usually available within 2 days. Normal: The radioactive tracer is evenly spread among the bones. No areas of too much or too little tracer are seen.
Generally, bone cancer is much easier to cure in otherwise healthy people whose cancer hasn't spread. Overall, around 6 in every 10 people with bone cancer will live for at least 5 years from the time of their diagnosis, and many of these may be cured completely.
The radioactive material (contrast) may be needed sometimes and not always with an MRI. An MRI creates 3D images of the bone, whereas a bone scan creates two-dimensional (2D) images. The MRI provides a detailed view of the bone and its surrounding structures such as the ligaments, tendons and soft tissue.
Radiographic features of OS vary depending on the level of osteoblastic activity. This is especially true for bone scans. Non-osseous lesions are better identified when osteoblastic activity produces ossification. Although rare, mineralized lymph nodes are more readily detected on bone scan than non-mineralized nodes2.
Bone scanning with 99mTc complexes is a safe, simple, and sensitive screening procedure for detecting both extensive and focal lymphomatous involvement of the skeletal system and is a useful means of following such involvement in response to treatment.
Pain in the area of the tumor is the most common sign of bone cancer. At first, the pain might not be there all the time. It may get worse at night or when the bone is used, such as when walking for a tumor in a leg bone. Over time, the pain can become more constant, and it might get worse with activity.
Rarely, people with a bone sarcoma may have symptoms such as fever, generally feeling unwell, weight loss, and anemia, which is a low level of red blood cells.
Biopsy. The most definitive way of diagnosing bone cancer is to take a sample of affected bone and send it to a laboratory for testing. This is known as a biopsy. A biopsy can determine exactly what type of bone cancer you have and what grade it is.
It occurs most often in young people (ages 10 to 30), but can occur in older people. Chondrosarcoma is cancer of the cartilage and is the second most common type of bone cancer. It accounts for about 25% of all bone cancers in the US. Chondrosarcoma is rare in young people, occurring mostly in adults age 50 and over.
Types of bone cancer
Primary bone cancers are the most serious of all bone cancers. They form directly in the bones or surrounding tissue, such as cartilage.
Bone scan can provide early detection of primary cancer and cancer that has spread to the bones from other parts of the body. Bone scan can detect osteomyelitis, an infection of the bone or bone marrow. Bone scan helps monitor the effects of treatment on bone abnormalities.
A bone scan is a test that can help doctors diagnose problems with your bones. It is a useful tool for finding cancer that has started in or spread to the bone. It can also help your doctor check how well treatment is working for cancer in the bone.
When choosing between a bone scan versus MRI for cancer detection, providers typically prefer an MRI. Because MRIs can reveal abnormal appearance or physical abscess in bones, they are more effective at detecting bone cancer than traditional bone scans.