For most people, the nausea was mild and temporary. You're more likely to have nausea when you first start Ozempic treatment or after your doctor increases your dose. For most people, this side effect goes away within a few days or weeks.
Nausea. Nausea was the most common side effect of Ozempic noted in clinical studies [4]. This is often described as an unsettled feeling in your stomach — or an upset stomach where you feel like you may need to vomit, but it may not always lead to vomiting.
Semaglutide (Ozempic, Wegovy, Rybelsus) can cause side effects that some people are unable to tolerate. Following dosing guidelines can help manage these side effects. Nausea, vomiting, and diarrhea are the most common semaglutide side effects.
Stop using Ozempic® and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or very rapid heartbeat.
Common Side Effects of Ozempic
“The most common side effects are gastrointestinal in nature: nausea, vomiting, diarrhea and constipation.” While the majority of people who take Ozempic will most likely experience these symptoms at some point during their treatment, they should subside over time, continues Dr. McGowan.
Once you begin using Ozempic, some people can find it takes several weeks to see any weight loss, yet others may see some weight loss within a week or 2. While it can be difficult, try to remain patient — change looks different for everyone.
It's possible to feel fatigued when taking Ozempic. During clinical trials, a small number of participants—less than 0.4%—reported feeling tired while taking Ozempic. People might experience fatigue more often within the first few weeks of treatment.
You should inject Ozempic once a week — on the same day of the week, every week. It doesn't make a big difference whether you take it in the morning or at night.
It may last for a few weeks while your body gets used to the medication and while your dose is increasing. Fatigue may be caused by other factors, however, so how long it lasts can vary. Lower your sleep debt and get in sync with your circadian rhythm to boost your energy levels.
“Ozempic face” is a term for common side effects of the type 2 diabetes medication semaglutide (Ozempic). It can cause sagging and aging of facial skin. A doctor may recommend lifestyle modifications or facial fillers to treat these effects.
It is important to have your blood sugar levels checked regularly. This is the only way to know if Ozempic is working properly for you. Your doctor will recommend how frequently you should do this.
Ozempic can cause other digestive side effects, such as gas, burping, bloating, diarrhea, and constipation. These side effects may affect your belly pain. Belly pain can also be a symptom of pancreatitis (inflammation of your pancreas). This is a rare but serious side effect of Ozempic.
Will Ozempic or Wegovy reduce belly fat? The answer appears to be yes. That Novo Nordisk-funded study of almost 2,000 overweight or obese adults without diabetes also found their visceral fat — the type that accumulates in the belly — was reduced from baseline with semaglutide, along with their total fat mass.
Some calorie-dense foods, including high-fat and fried foods, may make some side effects of Ozempic worse. Though calorie-dense foods aren't off-limits when taking the medication, they may not be encouraged as part of a weight-loss-promoting diet.
You'll likely notice some changes in appetite and reductions in food cravings within the first week.
Nausea and Vomiting
The reason behind these unpleasant symptoms is that Ozempic slows down the movement of food through your stomach and intestines. This can occur particularly during the first few weeks of starting the medication as your body adjusts to the medication.
Ozempic can make some people feel tired, but this is rare, and typically resolves over time. Digestive upset is a more common side effect, and it also tends to improve as your body adjusts.
How can I maximise my body weight loss on Ozempic? You can assist Ozempic by lowering your overall calorie intake, moving your body where possible and limiting your alcohol consumption.
The active ingredient in Ozempic is semaglutide, which works by inducing satiety. This feeling of being satisfied or “full”, suppresses appetite. This is why it works for weight loss.
The prescription drug Ozempic helps people with diabetes control their blood sugar. But its wild popularity is due to a side effect: rapid weight loss.
Ozempic works by stimulating the pancreas to release insulin, and also stops your liver from producing glucagon. This increases your insulin sensitivity while reducing your insulin resistance. It also slows down digestion and gastric emptying, helping you to feel fuller for longer.
Some individuals may actually gain more weight after stopping an obesity drug than they initially lost, Conde-Knape added. Studies have similarly shown weight rebound in people who stop taking Ozempic.
According to the FDA, they've received reports that patients taking the compounded version of Ozempic have had “adverse effects.” They also noted people could be using doses of semaglutide that are derived from a salt — which haven't been tested — rather than its pure form.