When it comes to whether you can take both magnesium and melatonin at the same time, the short answer is yes. Since both supplements have different effects on the body, they can be combined for improved sleep quality. However, be careful not to exceed the recommended doses of either supplement.
You can also try magnesium supplements to improve sleep, Dimitriu says. The recommended supplement dose is between 270 mg to 350 mg for men and 280 mg to 300 mg for women. However, do not exceed the upper tolerable limit of 350 mg a day or you may experience abdominal cramps and diarrhea.
Magnesium supplementation improves sleep efficiency, sleep time and sleep onset latency, early morning awakening, and insomnia objective measures such as the concentration of serum renin, melatonin, and serum cortisol, in older adults [8].
NSAIDs such as ibuprofen (Advil, Motrin) may lower levels of melatonin in the blood. Steroids and immunosuppressant medications. Melatonin may cause these medication to lose their effectiveness. DO NOT take melatonin with corticosteroids or other medications used to suppress the immune system.
Melatonin is a hormone that influences circadian rhythms, or the body's internal clock. Both melatonin and magnesium can help you fall asleep faster and stay asleep longer, but magnesium may be better at improving overall sleep quality.
Is it OK to take magnesium every night? You really shouldn't. Insomnia can be a sign of an unidentified sleep disorder, Gurubhagavatula said. You may find you have sleep apnea, restless legs, narcolepsy or a circadian rhythm sleep disorder.
Regardless of whether it truly helps with sleep or not, Dr. Ramkissoon doesn't recommend taking melatonin long-term.
Taking too much melatonin can actually cause rebound insomnia —either rendering the supplement ineffective or worse, exacerbating your already sleepless nights further. You only need tiny doses of melatonin to support your natural sleep cycle.
Do not use melatonin if you are pregnant or breastfeeding or have an autoimmune disorder, a seizure disorder or depression. Talk to your health care provider if you have diabetes or high blood pressure.
Melatonin significantly improved sleep quality (p = 0.04) compared to placebo, indicating that controlled-release melatonin may effectively facilitate discontinuation of benzodiazepine therapy while maintaining good sleep quality.
“Essentially, magnesium helps set the stage for sleep by calming the body and preparing it to sleep,” says Harris. Melatonin, on the other hand, when taken directly, impacts your body's circadian rhythm and hormonal regulation of sleep.
Magnesium helps relax muscles and calm the brain, which can help you to sleep better. But, unlike melatonin, it won't actually make you drowsy or feel sleepy.
Magnesium glycinate, which combines the mineral with the amino acid glycine, is the most popular and well-researched combination for treating sleep disorders and helping to reduce anxiety, depression, and stress.
How long does it take for magnesium to work for sleep? The benefits of magnesium are often associated with long-term use, so it's important to take your supplement consistently. We recommend daily use for at least three months to see the full effects on sleep.
In the UK and most of Europe, it's classed as a medicine, not a health supplement and as such, requires a prescription. This is because melatonin is considered “medical by function” which means that it requires a drug licence.
On average, melatonin takes effect within 30–60 minutes. OTC melatonin can stay in the body for 4–10 hours, depending on the dose and formulation. People should avoid taking melatonin at or after their intended bedtime. Doing so can shift their sleep-wake cycle and lead to daytime sleepiness.
Michael Breus, PhD, a sleep specialist and clinical psychologist, explained that, while taking melatonin is generally safe and may help you fall back asleep, popping the supplement after you've already gone to bed can cause you to feel groggy in the morning, which sort of defeats the purpose of taking it in the first ...
The morning after taking melatonin
If you've gotten a full night's sleep, but still feel groggy when you wake, you may be taking too large of a dose of melatonin. Reduce your dose next time to see if that helps.
Experts recommend taking melatonin about four to five hours before your normal bedtime to bring your circadian rhythm forward, and taking it around your usual wake up time to push it back. The dose makes a difference, too.
In several clinical trials, melatonin was found to be well tolerated and not associated with serum enzyme elevations or evidence of liver injury. Despite wide scale use, melatonin has not been convincingly linked to instances of clinically apparent liver injury.
How many 10 mg melatonin should you take? In adults, 10 mg is the maximum recommended dosage. However, most people do not need doses of melatonin this high. While there is no risk of addiction, research shows that melatonin administration is effective at the lowest dose for the short term.