If you take prednisolone for a long time, especially at a high dose, you may experience significant side effects. If you want or need to stop taking prednisolone, ask your doctor how to reduce the dose gradually to avoid serious side effects.
How long to take it for. This depends on your health problem or condition. You may only need a short course of prednisolone for up to 1 week. You may need to take it for longer, even for many years or the rest of your life.
There's no limit on how long you can take prednisone. It depends on the condition being treated and the dosage. It could be as short as 3 to 5 days or up to several months or even years.
Key takeaways: Corticosteroids — like prednisone — can have serious long-term side effects. This is especially true when someone takes them for a long time or at a higher dose. Examples of corticosteroids side effects include weight gain, osteoporosis, eye problems, and increased infection risk.
Serious side effects associated with higher doses and long-term use (greater than 1 month) are impaired wound healing, decreased growth (in children), decreased muscle production, fat deposits, stomach ulcers or bleeding, vision problems, higher risk for infection, and in rare cases life-threatening allergic reactions.
Facial hair growth (especially in women); high blood pressure and other cardiovascular effects; an increased appetite which may result in weight gain; slow skin healing and skin thinning; osteoporosis (brittle bones); the onset of diabetes; and stomach ulcers are associated with moderate-to-long term use.
The fear of using corticosteroids is so common that it has its own name: corticophobia. For topical steroids, this fear stems from well-known and severe adverse effects like Cushing syndrome and permanent skin atrophy.
For example, a 1–2 week course is often prescribed to ease a severe attack of asthma or gout. This is usually taken without any problems. Side effects are more likely to occur if you take a long course of steroids (more than 2–3 months), or if you take short courses often.
Taking prednisolone for a long time can lead to side effects such as: thinner bones (osteoporosis) poorly controlled diabetes. eyesight problems.
The amount of prednisone it takes to overdose isn't known. However, National Institutes of Health experts state that sustained prednisone use at 40 mg daily can cause adverse effects. There are no recorded reports of someone accidentally overdosing by taking large doses of prednisone.
Restlessness: In addition to mood changes, prednisone can increase energy levels. Some people may not mind this side effect, but others may feel unpleasantly jittery. It can also make you feel like it's harder to concentrate. Sleep disturbance: Prednisone keeps some people awake.
“Some say it's okay for an RA patient to take 5 mg of daily for years if need be, while others think prednisone is dangerous and want their patients off it completely,” Dr. Tiliakos says. “I'm of the school of thought that it's acceptable to take 5 mg for long periods of time, though it depends on the patient.”
However, prolonged use can cause immunosuppression, muscle wasting, bone changes, fluid shifts, and personality changes. For these reasons, prednisone is usually only prescribed short-term.
Prednisone generally works very quickly — usually within one to four days — if the prescribed dose is adequate to reduce your particular level of inflammation.
Self-care tips: Low cholesterol diet may help. If you develop signs suggesting heart problem, such as chest pain, get medical attention quickly. Work with your physician to address any heart risks that can be modified, such as exercise, weight and cholesterol level.
There is no set limit on how long you can safely take prednisone. It depends on the dose of prednisone and the condition being treated. It may be prescribed short term or long term. The dosage will be adjusted or stopped based on your response or lack of response to the medication.
Yes. Prednisone is one of several medications known to cause weight gain. This is usually more likely to happen with long-term use or higher doses. For example, about 70% of people in one study who took oral corticosteroids (including prednisone) for over 60 days reported weight gain.
Official answer. Prednisone does not usually cause sleepiness but may make you feel dizzy, irritable with mood swings, or cause you to have trouble sleeping (insomnia). If your dose is stopped too quickly or if you take prednisone for a long period of time you may feel severely fatigued.
Still, dexamethasone is more potent (stronger) than prednisone. If you're in a situation where you need a more potent steroid, dexamethasone will likely be the preferred option between the two. It also works longer in your body than prednisone does.
People taking prednisone can also experience higher blood sugar, which is a special concern for those with diabetes. Because prednisone suppresses the body's immune system, it can also increase the risk of infection.
Compromised immune system
Turns out, prednisone's greatest asset is also its greatest weakness. The very action that makes prednisone so effective — its ability to mute the immune system and relieve symptoms — can also lead to an increased risk of illness and infection, since your body's defenses are low.
Side effects of prednisone and other corticosteroids range from mild annoyances to serious, irreversible organ damage, and they occur more frequently with higher doses and more prolonged treatment. Common side effects include: Retention of sodium (salt) and fluid. Weight gain.
According to the Centers for Disease Control and Prevention, oral and intravenous corticosteroids reduce the activity of the immune system, and people who take them may be at an increased risk for severe illness from the virus that causes COVID-19.