Most people should expect to lose at least 5% of their starting body weight when using Ozempic for weight loss.
So, on average, with the recommended starting Ozempic dose of 0.25 mg, a 500 to 1000 calorie reduced diet, and exercise 3 times a week, you can expect to lose 3-5 pounds in the first month of treatment, which works out to about 3% of body weight for most overweight or obese individuals.
Although steady state levels are reached in 4 to 5 weeks, clinical effectiveness with Ozempic will vary from person to person and may take longer due to unique factors such as age, weight, amount of body fluid, additional medications you take, kidney or liver function, or your other medical conditions.
Ozempic has become famous for its weight loss potential, with people losing as much as 7% of their body weight on 1 mg Ozempic within a year or so of taking the medication. And, follow-up studies show they continue losing weight two years after starting the medication.
How much weight will I lose with Ozempic? About a third of people who take Ozempic for weight loss will lose 10% or more of their body weight. Most people should expect to lose at least 5% of their starting body weight when using Ozempic for weight loss.
A study found that at the highest dose of Wegovy (2.4 mg), patients lost on average 15% of their total body weight after 1 year. In patients with diabetes, one study showed that taking Ozempic at the highest dose of 2 mg led to on average ~15 lbs (6.9 kg) weight loss after 40 weeks.
Still, Ozempic and other GLP-1 medications will be most effective for weight loss and blood sugar control when combined with a healthy diet and regular exercise. Generally, eating healthy foods and avoiding foods high in sugar, calories, and unhealthy fats while taking Ozempic helps.
Ozempic isn't approved for weight loss. But because of how it works, some people taking Ozempic lose weight as a side effect. If you don't have diabetes, taking Ozempic for weight loss is considered an off-label use. Wegovy, a higher-dose version of Ozempic, is approved to help people manage their weight.
Ozempic is also used off-label for weight loss. In particular, it can help reduce the amount of belly fat. This is because Ozempic works by making you feel fuller for longer, which can help you resist overeating by controlling cravings and hunger.
Once you use Ozempic, you should experience increased satiety, which helps your body to gradually adjust and begin to lose weight. In general, most people lose a minimum of 5% of their starting weight when they use Ozempic.
In summary, Ozempic can make you feel tired, but it's a rare side effect. In the long-term, you may notice the opposite: energy increases and you're less tired, as you lose weight and improve cardiovascular health while taking Ozempic combined with physical activity and diet changes.
You start feeling those usual hunger pangs again, and consequently, you may start eating more to satisfy that hunger. An increase in your consumption can lead to the regaining of weight that was lost. A 2022 study found that most individuals gain weight back a year after stopping the medication.
Incorrect Calorie Intake
While Ozempic can help with weight loss, it is not a “magic pill”. It won't work if you are still intaking more calories than your body burns. Calorie intake plays a significant role in weight loss. A caloric deficit is necessary alongside Ozempic supplementation to reach your physique goals.
Study 2: Patients using the Ozempic 1 mg dose lost on average 12 lb (5.5 kg), and those using the 2 mg dose lost 14 lb (6.3 kg).
With Calibrate, members can expect to start seeing results after a couple of weeks of tapering up on the medication. You'll likely notice some changes in appetite and reductions in food cravings within the first week.
Ozempic can cause nausea and vomiting if taken after eating foods high in fat or sugar. It is recommended that you take Ozempic before meals, rather than after, to minimise any potential side effects from eating high-fat or high-sugar foods.
Ozempic® should be administered by a patient once weekly on the same day each week, at any time of the day, with or without meals. The day of weekly administration can be changed if necessary as long as the time between 2 doses is at least 2 days (>48 hours).
The maximum dose of Ozempic is 2 mg, administered once weekly on the same day and at the same time. It can be taken both with and without food. You can change the day of the week that you take Ozempic, as long as your last dose was taken 2 or more days before.
A dose of 0.5 to 1 mg per week (double the maximum approved diabetes dose) seems to provide the maximum weight loss benefits for many people using Ozempic off-label.
Patients trying to lose weight with either drug should work with a dietitian for a guided meal plan, but in general, they should aim to eat 1,200 to 1,800 calories a day depending on their initial weight, Rubin says.
Ozempic and its sister medication, Wegovy — approved for weight loss for people who are obese or overweight with weight-related medical conditions — are considered long-term or lifelong treatments.
Can I enjoy a drink while on Ozempic medication? The short answer is yes: You can drink alcohol while taking Ozempic.