It's fine to take painkillers such as paracetamol or ibuprofen while you're taking Hiprex.
It may also be recommended to avoid citrus fruits and juices (e.g., orange, grapefruit, lemon), milk and dairy products, and antacids during treatment with Hiprex, as these products may decrease the effectiveness of the medicine.
Tell your doctor right away if you have any serious side effects, including: mouth sores, unusual headache, ringing in the ears, muscle cramps, swelling of the arms/legs. A very serious allergic reaction to this drug is rare.
Hiprex is a urinary antibacterial agent with a wide antibacterial spectrum covering both gram-positive and gram-negative organisms. Urinary antibacterial activity can be shown within 30 minutes of administration.
Dosage for Hiprex
The dose of Hiprex for adults and children over 12 years of age is 1 tablet (1.0 g) twice daily (morning and night).
Hiprex is an antibacterial medicine used to treat or prevent bladder infections in adults and children at least 6 years old.
Hiprex may cause serious side effects including: painful urination, increased urination, blood in the urine, and.
The recommended dose is one tablet twice a day. If you have a catheter your doctor may increase your dose to one tablet three times a day. Not for children aged under 6. Children aged 6 – 12 years the recommended dose is half a tablet (500mg) twice a day.
Hiprex should be started after you have finished treatment of your current UTI. It is important to let your health professional know if you are taking any other treatments or over-the-counter medicines for your UTI as some medicines may lessen the effectiveness of Hiprex if taken at the same time.
Methenamine hippurate tablets are most effective in an acidic environment. Ural Effervescent Powder is a urinary alkaliniser and will make your urine less acidic, thus compromising the effectiveness of the methenamine hippurate tablets.
Urine has continuous antibacterial activity when HIPREX is administered at the recommended dosage schedule of 1 gram twice daily. Over 90% of methenamine moiety is excreted in the urine within 24 hours after administration of a single 1-gram dose.
Avoid most fruits (especially citrus fruits and juices), milk and other dairy products, and other foods that make the urine less acid. Also, avoid antacids unless otherwise directed by your doctor.
Hiprex is an antibacterial medicine that can be taken on a long-term basis to treat and prevent urinary tract infections (UTIs), for example, if you frequently get UTIs or if you have a catheter. Hiprex can be bought over-the-counter from pharmacies.
Recurrent UTIs (RUTI) are mainly caused by reinfection by the same pathogen. Having frequent sexual intercourse is one of the greatest risk factors for RUTIs. In a subgroup of individuals with coexisting morbid conditions, complicated RUTIs can lead to upper tract infections or urosepsis.
You can take Hiprex with or without food, but should avoid using the following medications as they may make Hiprex less effective. Note: If you are taking any prescription medicines, please consult your health professional before taking Hiprex.
These medications are generally well tolerated, although some women discontinued use because of a sensation of urethral burning caused by chemical irritation.
Can I take Hiprex with other medicines? Do NOT use antacids or urinary alkalinizers eg Ural while you are taking Hiprex. These cause your pee to be alkaline (opposite to acidic) which makes Hiprex ineffective.
DON'T drink coffee, alcohol or caffeine until the infection is gone. These drinks can irritate your bladder. DO drink a shot of sugar-free cranberry juice, if you like it. Cranberry juice may help fight infection, though the effectiveness is still being studied.
Additionally, a number of common foods and drinks — artificial sweeteners, spicy foods, alcohol, coffee, acidic fruits, citrus, or caffeinated drinks — can irritate your bladder, and may worsen UTI symptoms — so you should steer clear of them if you have signs of a bladder infection.
Large doses of methenamine hippurate (Hiprex) (higher than recommended) can cause bladder irritation, frequent and painful urination, protein in your urine, and blood in your urine.
WHAT ARE THE SIDE EFFECTS OF HIPREX ® (methenamine hippurate tablets USP)? Tell your doctor immediately if any of these serious side effects occur: an allergic reaction (shortness of breath; closing of the throat; swelling of the lips, face, or tongue; or hives. lower back or side pain.
If you experience any discomfort, your doctor may prescribe an analgesic, such as phenazopyridine, a pain-relief medication for the urinary tract. Others include those that reduce bladder spasms and over-the-counter pain relievers, such as acetaminophen or nonsteroidal anti-inflammatory drugs (NSAIDs).
Nonsteroidal anti-inflammatory drugs, such as ibuprofen (Advil, Motrin IB, others) or naproxen sodium (Aleve), to relieve pain. Tricyclic antidepressants, such as amitriptyline or imipramine (Tofranil), to help relax your bladder and block pain.
To help ease symptoms of a urinary tract infection (UTI): take paracetamol up to 4 times a day to reduce pain and a high temperature – for people with a UTI, paracetamol is usually recommended over NSAIDs such as ibuprofen or aspirin.
Gepotidacin's positive phase III data shows potential to be the first in a new class of oral antibiotics for uncomplicated urinary tract infections in over 20 years.