Blood tests are not used to diagnose lymphoma, but they can sometimes help determine how advanced the lymphoma is.
Complete blood count (CBC).
This test measures the number of blood cells in a sample, including red blood cells, white blood cells, and platelets. A low level of red blood cells, white blood cells or platelets may indicate that the lymphoma is present in the bone marrow and/or blood.
In cancer care, this blood test can be used to help diagnose a cancer or monitor how cancer or its treatment is affecting your body. For example, people undergoing chemotherapy often receive regular CBCs. In cancer care, a CBC is used to: Help diagnose some blood cancers, such as leukemia and lymphoma.
The best way to find lymphoma early is to pay attention to possible signs and symptoms. One of the most common symptoms is enlargement of one or more lymph nodes, causing a lump or bump under the skin which is usually not painful. This is most often on the side of the neck, in the armpit, or in the groin.
Common symptoms of having lymphoma include swelling of lymph nodes in your neck, in your armpits or your groin. This is often but not always painless and often could be associated with fevers, or unexplained weight loss, or drenching night sweats, sometimes chills, persistent fatigue.
Other common non-Hodgkin lymphoma symptoms
Night sweats (often soaking the sheets) and/or chills. Persistent fatigue, lethargy, weakness. Loss of appetite, nausea, vomiting. Abdominal pain or swelling, or a feeling of fullness.
Low-Grade Lymphoma
These grow so slowly that patients can live for many years mostly without symptoms, although some may experience pain from an enlarged lymph gland. After five to 10 years, low-grade disorders begin to progress rapidly to become aggressive or high-grade and produce more severe symptoms.
The most common sign of lymphoma is a lump or lumps, usually in the neck, armpit or groin. These lumps are swollen lymph nodes, sometimes known as 'glands'. Usually, they're painless. Fatigue is different to normal tiredness.
NHL is a disease that usually comes on suddenly and gets worse quickly. Symptoms vary depending on where tumor(s) are. These are the most common locations and their symptoms: Abdomen – pain, swelling, fever, anemia, tiredness, weight loss, vomiting, diarrhea, constipation, and irregular periods.
Most types of lymphoma can't be diagnosed by a blood test. However, blood tests can help your medical team find out how lymphoma and its treatment are affecting your body.
Cancer can lead to a high or low WBC count, depending on the type of cancer, which type of white blood cell is affected, and where the cancer is in your body.
Certain areas of skin may also thicken, harden and form plaques that itch and ulcerate. Typically, these plaques develop on the face or buttocks or within skin folds. As a skin lymphoma rash progresses, papules (small bumps) may start to appear.
The only way to be absolutely sure of a diagnosis of lymphoma (or any other cancer) is for a doctor to conduct medical tests including performing an excisional biopsy to remove an entire lymph node or an incisional biopsy to remove a portion of the diseased tissue.
Hodgkin lymphoma most commonly affects lymph nodes in the neck or in the area between the lungs and behind the breastbone, which is called the mediastinum. It can also begin in groups of lymph nodes under an arm, in the groin, or in the abdomen or pelvis.
Cancer-related fatigue is exhaustion that's at a much higher level than would usually be expected – you might feel tired very quickly after doing quite little. It can be physical, emotional or mental exhaustion.
Cutaneous T cell lymphoma
Many types of CTCL start as flat red patches on the skin, which can sometimes be itchy. With darker skin, the patches may appear lighter or darker than the surrounding skin. In the early stages, the skin patches can look like other common conditions such as eczema or psoriasis.
A lymphoma misdiagnosis is especially problematic because your lymphatic system regulates your immune system. There's a good chance a doctor can treat it when caught early. However, a misdiagnosis or a delay in diagnosis means you are missing out on valuable treatment time, which can lead to a rapid spread of cancer.
If left untreated, the disease can lead to death. If you decline life-saving treatment, you can choose to get support from palliative care (a medical team that manages your symptoms and pain). Later, hospice can support you in the final months to help you manage your quality of life.
Signs of lymphoma can include: Enlarged lymph node in the neck, shoulder or chest (most common symptom) Enlarged liver or pain on the upper left side of the abdomen. Enlarged spleen or pain on the upper right side of the abdomen.
Some people experience lower back pain that is unexplained. It is thought that this may be caused by expanding lymph nodes pressing on nerves.
Lymph nodes can swell for a variety of reasons and are considered to be enlarged if they are bigger than 1.5 centimeters in diameter, or slightly larger than a pea. Typically, lymph nodes that are enlarged due to lymphoma are much bigger and can grow to be the size of a grape (or larger).