Panadol Night hasn't been universally discontinued but faced temporary removals, particularly in the UK/EU, due to regulatory scrutiny over its antihistamine (diphenhydramine) content's potential for dependency, leading to reformulation with lower doses; in Australia, specific blister pack types were cancelled by the manufacturer (Haleon) for administrative reasons under TGA rules, not a product failure, with similar formulations still available.
The original Panadol Night Pain was discontinued and replaced with Panadol Night tablets. They are essentially the same medication, containing the same ingredients. Panadol Night is available to buy via our online checkout system.
Panadol Night may cause drowsiness, dizziness, difficulty concentrating or blurred vision which means that you should not drive or operate machinery after taking the tablets. You should not take Panadol Night at the same time as other medicines containing antihistamines.
This medicine is available without prescription, but you still need to use Panadol Night carefully to get the best results from them. Keep this leaflet you may need to read it again. If you have any questions, or if there is anything you do not understand, ask your pharmacist.
Panadol Night tablets combines paracetamol 500mg and diphenhydramine hydrochloride 25mg. Paracetamol relieves pain and can reduce fever. Diphenhydramine hydrochloride is an antihistamine which can cause sleepiness, which is why Panadol Night should only be taken at bedtime.
You may feel drowsy for about 4-6 hours, but this can differ depending on the person. The best way to combat drowsiness caused by Benadryl (if this isn't the goal) is to simply take a non-drowsy antihistamine like Zyrtec or Claritin. If drowsiness is the goal, you may want to take it about 30 minutes before bedtime.
Active ingredient: paracetamol + diphenhydramine
There's no single "best" sleeping pill; the right choice depends on your needs (falling asleep vs. staying asleep, short vs. long-term), with popular prescription options including zolpidem (Ambien) for falling asleep and temazepam (Restoril) for both falling and staying asleep, while over-the-counter options like melatonin and antihistamines (diphenhydramine) offer milder help, though always consult a doctor for personalized, safe, and effective treatment, especially for chronic issues.
In summary, I would suggest an oral, 2nd or 3rd generations antihistamine (e.g. cetirizine, desloratadine, fexofenadine, levocetirizine, loratadine).
The relative risk of a serious cardiovascular event in patients taking diclofenac versus non-use of NSAIDs ranged from 1.4–1.6. This means those using diclofenac were approximately 1.5 times more likely to have cardiovascular complications than someone not using diclofenac.
This medicine contains codeine and can cause addiction if you take it continuously for more than three days. When you stop taking it you may get withdrawal symptoms. You should talk to your doctor or pharmacist if you think you are suffering from withdrawal symptoms.
Diphenhydramine is sold under the brand name Benadryl by McNeil Consumer Healthcare in the US, UK, Canada, and South Africa. Trade names in other countries include Dimedrol, Daedalon, Nytol, and Vivinox. It is also available as a generic medication.
Panadol NightPain with paracetamol and diphenhydramine provides effective relief from night time pain to help you feel better and sleep better.
Even though you can readily get this over-the-counter to treat various allergic issues, this is an older medication that also not only has antihistamine effects, but anticholinergic effects that can create significant side effects, such as dry mouth, drowsiness, difficulty concentrating, urinary retention and ...
Paracetamol pack sizes changing
As of 1 February 2025: Nationally, packs of paracetamol-containing products available for general sale in supermarkets and convenience stores will contain a maximum of 16 capsules or tablets.
The day tablet helps relieve body aches and pains, a runny or blocked nose and a dry cough so you can feel better sooner. The night tablet also contains an antihistamine that helps you rest by providing temporary relief from these symptoms.
In Australia, the "best" sleeping tablets depend on your needs, but prescription options like Temazepam, Zopiclone (Imovane), and Zolpidem (Stilnox) (for short-term use) are common, while Suvorexant (Belsomra) suits chronic cases, and Circadin (Melatonin) (for over 55s) is an over-the-counter alternative, but always consult a doctor for proper diagnosis and safest, most effective treatment.
The 2023 American Geriatrics Society (AGS) Beers Criteria for Potentially Inappropriate Medication Use in Older Adults recommends that individuals 65 years or older avoid use of first-generation antihistamines, including oral diphenhydramine.
Keep light, noise and the temperature at levels that are comfortable and won't disturb your rest. Don't do activities other than sleeping or sex in your bedroom. This will help your body know this room is for sleeping. Put clocks in your bedroom out of sight.
Daridorexant is one of a relatively new class of drugs that have been developed for the treatment of insomnia. Its mechanism of action differs from many of the older insomnia treatments. Studies have shown that it can help people to fall asleep faster at night and stay asleep longer during the night.
Relax, unwind and try meditation to help you sleep
Avoid electronic devices at least an hour before bed, as mobiles, tablets and computers all throw out blue light that stops sleep. Reading, listening to soft music or a podcast, or sleep meditation can all help if you have trouble sleeping.
Furthermore, ramelteon was found to be about 10 times more potent than melatonin in promoting sleep.
Diphenhydramine hydrochloride is an antihistamine that helps you sleep. CHEMISTS' OWN NIGHT PAIN RELIEF is used to give temporary relief of pain when associated with sleeping difficulty. It is useful for headache, migraine, backache, arthritis, rheumatic and muscular pain, neuralgia, toothache, and period pain.
Quercetin. Quercetin is one of the best natural antihistamine substances. Most products, like garlic, contain the antioxidant quercetin. It interferes with the histamine response of the body by inhibiting mast cells, thus pacifying asthma symptoms and inflammation.
Sedating antihistamines — these can make you feel sleepy. They include: dexchlorpheniramine. diphenhydramine.