At night, the body releases more cytokines, which are immune system proteins that create inflammation. This can cause itching or make itching worse. At the same time, the body's production of corticosteroids, which tame inflammation, declines.
Dry skin: Your body loses moisture at night, which can make your skin itchy. Hormonal changes: At night, your body doesn't produce as many hormones as it does during the day and certain hormones reduce inflammation (swelling). As you have fewer hormones at night, your skin could be itchy.
Your skin naturally loses more water during the night as you're not staying hydrated while you sleep. This can cause your skin to become dry and dehydrated, leading to itching.
Dry, itchy skin is often a sign of a vitamin D deficiency. As vitamin D is created through skin exposure to the sun and cholesterol in the skin, in the winter months, when sunlight exposure is less, people often experience dry, itchy skin attributing it to the cold weather.
See your health care provider or a skin disease specialist (dermatologist) if the itching: Lasts more than two weeks and doesn't improve with self-care measures. Is severe and distracts you from your daily routines or prevents you from sleeping. Comes on suddenly and can't be easily explained.
What does diabetes itching feel like? If you have diabetes, itching can be intense. It's an irritating feeling that makes it hard not to scratch, but scratching can make the itch worse. You can itch anywhere, but if you have nerve damage (neuropathy) associated with diabetes, your lower legs may itch.
The causes of skin itching, or pruritis, are usually harmless. They are often temporary issues such as dry skin or a bug bite. Less commonly, nerves, kidneys, thyroid, or liver issues can cause itching sensations without necessarily causing a rash.
For mild itching, use calamine lotion. For a more intense itch, use hydrocortisone cream. Oral antihistamines can also help.
Yes, it really does make itching worse
Serotonin reacts with neuronal receptors that carry itch signals to the brain, making itching worse.
A nonprescription oral antihistamine, such as loratadine (Alavert, Claritin, others), cetirizine (Zyrtec Allergy, others) or diphenhydramine (Benadryl Allergy, others), may help relieve itching. Consider whether you might prefer a type that doesn't cause drowsiness. Ask your pharmacist about options. Apply cold.
Bile Salts- Those with liver disease may have higher levels of bile salt building up under the skin, which may cause itching.
Itching. Localized itching is often caused by diabetes. It can be caused by a yeast infection, dry skin, or poor circulation. When poor circulation is the cause of itching, the itchiest areas may be the lower parts of the legs.
Dry, itchy skin
High blood sugar (glucose) can cause this. If you have a skin infection or poor circulation, these could also contribute to dry, itchy skin.
Itching with kidney disease can be generalized, or it can occur in specific parts of the body. Common areas for this type of itching include the head, arms, back, and abdomen. It also tends to be worse at night, which can disturb your sleep.
What autoimmune disease causes an itchy rash? Some autoimmune diseases that may cause an itchy rash are cutaneous lupus, oral lichen planus, and erythrodermic psoriasis.
Chronic itch is a common yet hard-to-treat symptom of many inflammatory skin conditions, such as psoriasis. The urge to constantly scratch can seriously impair a person's quality of life and lead to permanent skin damage.
Disease Overview
Prurigo nodularis (PN) is a chronic inflammatory skin disease where an extremely itchy, symmetrically distributed rash appears most commonly on the arms, legs, the upper back and/or the abdomen. The itch associated with PN is so severe that it often interferes with sleep and psychological wellbeing.