People who are on blood-thinning medication, such as warfarin (Coumadin), clopidogrel (Plavix), and aspirin are typically advised against taking a curcumin or turmeric supplement, because the supplements can enhance the drugs' blood-thinning effects, perhaps to dangerous levels.
High doses of turmeric could have a blood-thinning effect; if taken on top of prescribed anticoagulants, this could increase the risk of dangerous bleeding. People with liver or bile duct problems should not take turmeric supplements, as they can increase bile production.
Taking turmeric supplements may put you at a higher risk of getting kidney stones. Don't take turmeric supplements if: You're taking aspirin, ibuprofen (Advil , Motrin ), or Acetaminophen (Tylenol ). Turmeric may lessen the effects of these medications.
Studies using high doses of curcumin have reported some mild adverse effects, including nausea, diarrhea, headache, skin rash, and yellow stool. Use of curcumin with piperine a black pepper extract may cause adverse drug reactions because piperine greatly increases intestinal permeability.
People who are on blood-thinning medication, such as warfarin (Coumadin), clopidogrel (Plavix), and aspirin are typically advised against taking a curcumin or turmeric supplement, because the supplements can enhance the drugs' blood-thinning effects, perhaps to dangerous levels.
The World Health Organization found 1.4 mg of turmeric per pound of body weight is okay for daily intake. It's not advisable to take high doses of turmeric for long periods of time. There isn't enough research to guarantee safety. If you want to take turmeric to relieve pain and inflammation, talk to your doctor.
Curcumin has significant anti-inflammatory effects, and a large number of preclinical or clinical researches have studied its effect on inflammatory diseases, among them, inflammatory bowel disease, arthritis, psoriasis, depression, atherosclerosis and COVID-19 are the focus of research hotspots.
Both in vitro and in vivo studies have shown, however, that curcumin may produce toxic and carcinogenic effects under specific conditions. Curcumin may also alter the effectiveness of radiotherapy and chemotherapy.
Most research says that taking in at least one gram of curcumin per day is necessary for measurable anti-inflammatory effects, Webster says.
Curcumin can raise the risk of uncontrolled bleeding if taken with aspirin, blood thinners (coumadin or heparin), nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen or naproxen, and anti-platelet medicines (clopidogrel, ticlopidine).
Magnesium is ideal when you're stressed or anxious or have trouble sleeping or when your muscles are tight and tense. Turmeric can help to support joint health, comfort and mobility so you can keep doing the things you enjoy. Together these two powerful ingredients help support both muscles and joints.
Side effects.
It can cause nausea and diarrhea, especially in high doses or after long-term use. It might also pose a risk of ulcers in high doses. As a topical treatment, it can cause skin irritation. Caution is advised when turmeric is taken by people known to have gallstones; consult your health care provider first.
Interactions. Turmeric or curcumin might also increase the effects of other blood sugar medications, which could lead to hypoglycemia, or low blood sugar. People should talk to a doctor before increasing their intake of turmeric or curcumin and before taking turmeric or any other supplements for their symptoms.
Cardiovascular. Turmeric or curcumin-containing preparations may cause heart rate or rhythm disorders.
Turmeric and curcumin have been associated with a low rate of transient serum enzyme elevations during therapy and while having a long history of safety, turmeric products have recently been implicated in over a dozen instances of clinically apparent acute liver injury.
Hormone-sensitive condition such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Turmeric contains a chemical called curcumin, which might act like the hormone estrogen.
However, curcumin and other turmeric diarylheptanoids are only weakly estrogenic and do not produce significant effects when turmeric is consumed in food.
Data of study indicate that garlic, gingrer and turmeric extracts allow free promotion of the estrogen stimulation that leads to increase cellular proliferation via upregulation of cyclin D1 levels and CDK4/6 activity, as well as c-myc, and cyclin E/CDK2 levels.
When can you expect to see results? In one study, participants reported improvements in joint discomfort after supplementing with 2 grams of turmeric daily for 6 weeks. Another study reported results after 8-12 weeks of supplementation with 1 gram of turmeric daily.
Curcumin is an active ingredient in turmeric and appears to have anti-inflammatory and blood-thinning or anticoagulant properties. A 2019 review in the EPMA Journal indicates that turmeric may help block blood clotting and advises caution when combining turmeric with blood-thinning drugs.
When it comes to taking turmeric, it takes a little while for the curcumin to build up in your system. However, once you've gone through a loading period, that's when you will start to notice some of the proposed benefits.
So what's the difference? Turmeric is a plant and it's the roots of the plant that are used to make the spice that is used in cooking and herbal drinks. Curcumin is the naturally occurring compound within the plant's roots that give it it's bright yellow colour and is known as a carotenoid compound.
Turmeric contains curcuminoids, which are bioactive compounds, and curcumin is one of these curcuminoid compounds. While turmeric contains only 2 – 9% curcuminoids, 75% of these active curcuminoids are curcumin, which is why curcumin is the “star” of turmeric.
Turmeric should be taken with meals to help with absorption. It's also a good idea to divide it into two doses taken 8 to 12 hours apart. This will help increase absorption and keep levels steady in the body. Dividing the dose may also help reduce possible side effects.