Ozempic® is more effective for weight loss and blood sugar improvements than Saxenda®. Studies have also shown that Ozempic® leads to fewer side effects and adverse events than Saxenda® with people tolerating Ozempic® better.
Both Saxenda and Ozempic are injectable medications used with diet and exercise. Ozempic is intended for people with type 2 diabetes, and Saxenda helps people with overweight or obesity manage weight loss. They are both GLP-1 agonists that help maintain blood sugar levels and curb appetite.
No. Doctors do not recommend you take both medications at the same time. Both Saxenda and Ozempic work to regulate your blood sugar levels and doubling up on this type of medication can lead to complications if your blood sugar drops too low.
Mounjaro is a more effective drug than Ozempic. As demonstrated above, tirzepatide (the active ingredient in Mounjaro) leads to more clinically significant weight loss and blood sugar reductions than semaglutide (the active ingredient in Ozempic).
Ozempic® is more effective than Saxenda® at supporting weight loss and blood sugar reductions. Ozempic® seems to lead to fewer side effects and is better tolerated than Saxenda®. However, individuals will vary in their response to medications, so choose the right one for you.
Wegovy® is a more effective drug than Saxenda®. As demonstrated above, semaglutide (the active ingredient in Wegovy®) leads to more clinically significant weight loss and blood sugar reductions than liraglutide (the active ingredient in Saxenda®).
Will Ozempic or Wegovy reduce belly fat? The answer appears to be yes. That Novo Nordisk-funded study of almost 2,000 overweight or obese adults without diabetes also found their visceral fat — the type that accumulates in the belly — was reduced from baseline with semaglutide, along with their total fat mass.
How Long Can You Stay on Ozempic (semaglutide)? A person can stay on Ozempic® so long as they are tolerating the medication and it is deemed appropriate by their treating provider. There is no specific time frame when someone should stop taking Ozempic as it is a medication that is intended for chronic (long-term) use.
You've hit a plateau
It's normal to eventually hit a point where your weight loss slows down, especially if you're not working on keeping or building up your muscle mass. Losing muscle along with fat slows your metabolism and can slow down your weight loss.
Some individuals may actually gain more weight after stopping an obesity drug than they initially lost, Conde-Knape added. Studies have similarly shown weight rebound in people who stop taking Ozempic.
You Will Regain Weight
“Ozempic should always be taken along with making healthy lifestyle changes in diet and physical activity,” Kushner says. “These changes should be continued even after stopping the medication and can help maintain some of the health benefits seen with body weight and blood sugar control.”
Teresa Shepherd said she lost 90 pounds while taking an off-brand version of the drug Ozempic for around eight months. Shepherd, who lives in Florida, told "Good Morning America" she has been able to maintain her weight loss two months after stopping the medication.
Several factors could be at play if you're taking Saxenda and not losing weight, including: Diet—Saxenda is approved in conjunction with a low-calorie diet, so if you haven't adjusted your diet accordingly, that could work against the weight loss you might otherwise be achieving.
Some people start seeing results from Saxenda in the first two to four weeks. You may lose about 2%—4% of your body weight. However, during clinical trials, people taking Saxenda saw a significant weight loss of at least 5% after eight weeks of treatment.
Mounjaro has been studied head-to-head against Ozempic. After 40 weeks, people taking it saw a better reduction in hemoglobin A1C levels (average blood sugar over 3 months) compared to Ozempic. And they lost more weight, too. Mounjaro is only approved to treat Type 2 diabetes for now.
Semaglutide (Ozempic, Wegovy, Rybelsus) can cause side effects that some people are unable to tolerate. Following dosing guidelines can help manage these side effects. Nausea, vomiting, and diarrhea are the most common semaglutide side effects.
Experts said they consider Ozempic and Wegovy to be lifelong medications.
“Ozempic face” is a term for common side effects of the type 2 diabetes medication semaglutide (Ozempic). It can cause sagging and aging of facial skin. A doctor may recommend lifestyle modifications or facial fillers to treat these effects.
The injectable medication acts just like this natural hormone to make you feel fuller for longer and reduces your cravings for more food. Enhancing the way your body regulates blood sugar levels and the storage of fat can help patients lose weight.
The most common side effects of Saxenda® in adults include nausea, diarrhea, constipation, vomiting, injection site reaction, low blood sugar (hypoglycemia), headache, tiredness (fatigue), dizziness, stomach pain, and change in enzyme (lipase) levels in your blood.
In studies, significant weight loss of at least 5% was seen after 8 weeks of treatment. After one year of treatment in adults, 85% of patients treated with Saxenda lost weight (an average of 21 lb. [9.5 kg] weight loss, or 9.2% of their weight). Your results may be different.