The use of chemicals, such as fluoride and chlorine, bind to magnesium, making the water supply low in the mineral, as well. Common substances — such as sugar and caffeine — deplete the body's magnesium levels.
Refining or processing of food may deplete magnesium content by nearly 85%. Furthermore, cooking, especially boiling of magnesium-rich foods, will result in significant loss of magnesium. The processing and cooking of food may therefore explain the apparently high prevalence of low magnesium intake in many populations.
One study found that very high doses of zinc from supplements (142 mg/day) can interfere with magnesium absorption and disrupt the magnesium balance in the body [17].
Magnesium assists your body in regulating zinc levels, but high intakes of zinc can be detrimental to magnesium absorption – only abnormally high doses (around 142 mg of zinc per day) will reduce magnesium absorption.
Causes of low magnesium. Low magnesium is typically due to decreased absorption of magnesium in the gut or increased excretion of magnesium in the urine. Low magnesium levels in otherwise healthy people are uncommon. This is because magnesium levels are largely controlled by the kidneys.
You might have trouble absorbing magnesium from food if you drink too much alcohol, have kidney problems, take certain medicines, or have celiac disease or long-lasting digestive problems. If you are low on magnesium for a long time and it becomes magnesium deficiency, which is rare, you may have: Poor appetite.
Mg is essential in the metabolism of vitamin D, and taking large doses of vitamin D can induce severe depletion of Mg. Adequate magnesium supplementation should be considered as an important aspect of vitamin D therapy.
Large doses of minerals can compete with each other to be absorbed. Don't use calcium, zinc, or magnesium supplements at the same time. Also, these three minerals are easier on your tummy when you take them with food, so if your doctor recommends them, have them at different meals or snacks.
Taking high levels of zinc (142 milligrams a day and up) in supplement form may interfere with magnesium absorption. If you are taking zinc at extremely high doses due to medical issues, take the zinc several hours before or after taking a magnesium supplement.
Acids and Alkalis.
Magnesium is rapidly attacked by all mineral acids except hydrofluoric acid (HF) and H2CrO4.
Hypokalemia and Hyperkalemia
Magnesium depletion typically occurs after diuretic use, sustained alcohol consumption, or diabetic ketoacidosis.
Magnesium does not react with water to any significant extent. This is in contrast with calcium, immediately below magnesium in the periodic table, which does react slowly with cold water.
High salt intake increases distal load of calcium and magnesium and PTH levels which attribute to upregulation of transport molecules. Low salt intake and fluid restriction decreased calcium and magnesium load to the DCT and downregulate transport molecules.
Can I take magnesium with other minerals and vitamins? Yes. Vitamins and minerals all work in combination and rely on each other to be fully effective. Taking magnesium helps your body to absorb and use minerals such as calcium, phosphorus and potassium, and vitamins like vitamin D.
Other experts caution against taking magnesium at the same time as other minerals. “It can interfere with absorption of other minerals, so if you take a multivitamin, calcium or zinc, take magnesium at a different time of day,” Cooperman warns.
Magnesium—just like calcium—is absorbed in the gut and stored in bone mineral, and excess magnesium is excreted by the kidneys and the faeces (Figure 4).
Yes! You can and should take magnesium and vitamin D together. In fact, the bioavailability of vitamin D largely relies on magnesium. Also, many nutrients wouldn't work efficiently without magnesium, further highlighting the importance of this mineral!
Magnesium and calcium/multivitamin
Additionally, she says to refrain from taking calcium, magnesium or zinc together as they will “compete for absorption.”
Inflammation uses up or depletes magnesium levels. Even low-grade inflammation is associated with higher magnesium requirements. The body requires magnesium to downgrade inflammation, and more inflammation may increase magnesium needs.
Although the functions of vitamin C and magnesium may not overlap like other nutrients, there's no harm in taking them simultaneously. With no known interactions, vitamin C and magnesium can safely be supplemented together.
This specific combination of magnesium and vitamin B6 in a 10:1 ratio has been shown to provide faster relief of magnesium-deficiency symptoms than magnesium alone in magnesium-deficient animals [12].
Magnesium absorption increased linearly from 28-39 per cent intake with increasing dietary vitamin D.
Chronic magnesium deficiency is often associated with normal serum magnesium despite deficiency in cells and in bone; the response to oral supplementation is slow and may take up to 40 weeks to reach a steady state.