What medications cause leg weakness?

Examples of medications that can cause muscle weakness include:
  • amiodarone (Cordarone)
  • antithyroid medications, such as methimazole (Tapazole) or propylthiouracil.
  • antiretroviral medicines, such as lamivudine (Epivir) or zidovudine (Retrovir)
  • chemotherapy medications.
  • cimetidine (Tagamet)
  • corticosteroids.

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What is the most common cause of leg weakness?

Muscle weakness in the legs may indicate a neuromuscular disease is present. These diseases lead to a loss of functioning in nerves and muscles throughout the body. They include muscular dystrophy, amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), myasthenia gravis and fibromyalgia.

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Can certain drugs cause muscle weakness?

A drug-induced or toxic myopathy is defined as the subacute, and rarely acute, manifestation of myopathic symptoms, such as muscle weakness, fatigue, myalgia, cramps, creatine kinase (CK) elevation, or myoglobinuria, that occurs in patients without muscle disease when exposed to therapeutic doses of certain drugs (90).

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What deficiency causes leg muscle weakness?

Muscle weakness due to vitamin D deficiency is predominantly of the proximal muscle groups and is manifested by a feeling of heaviness in the legs, tiring easily, and difficulty in mounting stairs and rising from a chair; the deficiency is reversible with supplementation (15–18).

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What is the best vitamin for leg weakness?

Vitamin D helps your body use calcium. But when you're deficient in this vitamin, your legs may feel weak, sore and heavy. A vitamin E deficiency may be another reason your legs feel heavy after a run.

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Peripheral Vascular Disease: Leg Weakness, Symptoms and Treatment

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What drugs affect your legs?

Medications are one of the most common causes of leg and ankle swelling. Examples include amlodipine, NSAIDs, and birth control pills. Gabapentin, pregabalin, and steroids like prednisone are also common culprits. Swelling in the legs and ankles from medications isn't usually dangerous.

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What is the blood test for muscle weakness?

Doctors use a blood test to look for elevated levels of a substance called creatine kinase, which is released into the bloodstream when muscle fibers deteriorate. Elevated levels may mean you have an inflammatory myopathy.

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Why do my legs feel weak when I walk?

Often, the cause of weakness or pain in the legs when walking is a narrowing of the space around nerves that carry signals to the lower part of the body. When symptoms affect your legs, the condition is typically lumbar spinal stenosis.

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Can heart problems cause weakness in legs?

As a result, people with heart failure often feel weak (especially in their arms and legs), tired and have difficulty performing ordinary activities such as walking, climbing stairs or carrying groceries.

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What does jelly legs mean?

SUMMARY: The “jelly legs” feeling, which typically refers to feelings of weakness, dizziness, or loss of control in the legs, is often caused by a rush of adrenaline taking blood away from the legs, though there may be other causes.

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Can leg weakness come and go?

Summary. Weakness in the legs is a common symptom of many health conditions and injuries, including autoimmune diseases, spinal conditions and injuries, and stroke. Often, leg weakness will resolve over time, but in some cases, it can be a medical emergency, especially if the weakness comes on suddenly.

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What is severe leg weakness in the elderly?

Sarcopenia is the age-related progressive loss of muscle mass and strength. The main symptom of the condition is muscle weakness. Sarcopenia is a type of muscle atrophy primarily caused by the natural aging process. Scientists believe being physically inactive and eating an unhealthy diet can contribute to the disease.

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Why do my legs feel weak and shaky?

People will often experience shaky or weak legs when dealing with vascular issues in the leg, like deep vein thrombosis or blood clots. Clots are very serious if untreated because they could break off into the bloodstream and travel to an artery in the lungs, blocking blood flow.

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What are the 3 main diseases that affect the muscles?

Primary Muscle Diseases
  • Myositis is an inflammation of muscles and their associated tissues, including blood vessels. ...
  • Myasthenia gravis (MG) is an autoimmune neuromuscular disease. ...
  • Amyotrophic lateral sclerosis (ALS) is also called Lou Gehrig's disease.

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Is muscle weakness a neurological problem?

Neuromuscular disorders include a wide-range of diseases affecting the peripheral nervous system, which consists of all the motor and sensory nerves that connect the brain and spinal cord to the rest of the body. Progressive muscle weakness is the predominant condition of these disorders.

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Can medication affect your legs?

Some medicines can cause leg problems. A few examples are: Birth control pills and estrogen. These can increase the risk of blood clots in the leg, which may cause pain or swelling.

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Can blood pressure medication affect your legs?

Most often prescribed for high blood pressure, ACE inhibitors are also known to cause leg cramps through potassium buildup. This can lead to achy muscles, joints, and even bones.

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What drugs paralyze legs?

Commonly Used Paralytic Drugs
  • Succinylcholine.
  • Rocuronium.
  • Vecuronium.
  • Mivacurium.
  • Atracurium.
  • Cisatracurium.

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Is magnesium good for leg weakness?

A four-year analysis by a team at the University of East Anglia found that a greater dietary intake of magnesium improved muscle strength, muscle mass and bone mineral density in men and women in older age groups.

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Does magnesium help tired legs?

Magnesium supplementation is often suggested for restless legs syndrome (RLS) or period limb movement disorder (PLMD) based on anecdotal evidence that it relieves symptoms and because it is also commonly recommended for leg cramps.

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Can too much vitamin D cause leg weakness?

Yes, getting too much vitamin D can be harmful. Very high levels of vitamin D in your blood (greater than 375 nmol/L or 150 ng/mL) can cause nausea, vomiting, muscle weakness, confusion, pain, loss of appetite, dehydration, excessive urination and thirst, and kidney stones.

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What causes sudden leg weakness in elderly?

Diabetes and atherosclerosis are the main causes of poor circulation in the body, but are also associated with smoking, living an inactive lifestyle, or having high blood pressure or cholesterol. To reduce lower extremity weakness, elevate your legs while your sitting or laying down to increase your bodies circulation.

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