Research has found that magnesium glycinate is one of the most absorbable forms, along with citrate, chloride, lactate, and aspartate5 . It is also important to note that zinc and calcium can reduce magnesium's absorption6 , so be mindful of what you take it with.
Magnesium Glycinate
This means that magnesium is combined with the amino acid glycine. Overall, the glycinate form absorbs better and is least likely to cause digestive distress.
Magnesium citrate is a more common choice if you want to maintain magnesium levels for general whole-body health. On the other hand, magnesium glycinate has less bioavailability but can have a calming effect.
Each has different advantages and disadvantages. For example, some types of magnesium are easier to absorb than others. Magnesium is one of the most common minerals in the body. It plays a role in over 600 metabolic reactions, including energy production, protein formation, and blood pressure regulation.
On the other hand, magnesium citrate is much better absorbed by the body than magnesium oxide. It appears to have a bioavailability of 25-30% (17). For this reason magnesium citrate is the most common type of magnesium supplementation and is the recommended choice for most issues and deficiencies.
Magnesium glycinate/glycerophosphate - best for sleep and anxiety. Magnesium glycerophosphate is ideal for stress relief and sleep. Glycerophosphate has the lowest rate of diarrhea, as compared to other forms of magnesium.
Magnesium citrate may be the most effective type if you want to try a supplement. If you're magnesium deficient, there may be other benefits from increasing your intake of this nutrient. And other remedies are available for leg cramping that may help.
High doses of magnesium from supplements or medications can cause nausea, abdominal cramping and diarrhea. In addition, the magnesium in supplements can interact with some types of antibiotics and other medicines.
Therefore, magnesium supplements can be taken at any time of the day, as long as you're able to take them consistently. For some, taking supplements first thing in the morning may be easiest, while others may find that taking them with dinner or just before bed works well for them.
People often use magnesium glycinate instead of other magnesium supplements, as the body finds it easier to absorb magnesium in this form. It is also one of the gentlest supplements on the stomach. Unlike other forms of magnesium, it might not cause as many side effects, such as an upset stomach or loose stools.
Liquids, powders, or some other forms of this product may contain sugar and/or aspartame. Liquid products may also contain alcohol. Caution is advised if you have diabetes, alcohol dependence, liver disease, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet.
Magnesium citrate causes the intestines to release water into the stool. This softens the stool and relieves constipation and irregularity. Magnesium citrate is more gentle than some of the other magnesium compounds and found as the active ingredient in many commercially available laxatives.
Yes! You can and should take magnesium and vitamin D together. In fact, the bioavailability of vitamin D largely relies on magnesium. Also, many nutrients wouldn't work efficiently without magnesium, further highlighting the importance of this mineral!
Mg is essential in the metabolism of vitamin D, and taking large doses of vitamin D can induce severe depletion of Mg. Adequate magnesium supplementation should be considered as an important aspect of vitamin D therapy.
Taking magnesium with these medications might cause blood pressure to go too low. Some of these medications include nifedipine (Adalat, Procardia), verapamil (Calan, Isoptin, Verelan), diltiazem (Cardizem), isradipine (DynaCirc), felodipine (Plendil), amlodipine (Norvasc), and others.
The claimed benefits of magnesium supplementation range from boosts in everyday wellness — better sleep, increased energy levels and improved mood — to specific health benefits, such as lower blood pressure, reduced risk of heart disease and improvement in migraines.
Magnesium Glycinate taken before and after exercise may help relieve sore muscles.
Too little potassium, calcium or magnesium in your diet can contribute to leg cramps. Diuretics — medications often prescribed for high blood pressure — also can deplete these minerals.
Leg cramps can be caused by a lack of magnesium in the body, and supplementing with magnesium can help to relieve them. Magnesium also helps to regulate nerve and muscle function, and can help to prevent other muscle-related issues such as spasms and twitches.
In order to fall asleep and stay asleep, your body and brain need to relax. On a chemical level, magnesium aids this process by activating the parasympathetic nervous system, the system responsible for getting you calm and relaxed ( 6 ).