There's no single "hardest" thing, but advanced Physics (Quantum Mechanics, Quantum Field Theory, String Theory, Quantum Gravity) and complex Chemistry (Physical Chemistry, Organic Chemistry) are often cited due to demanding math, abstract concepts, and huge knowledge bases, while Molecular Biology/Biochemistry is tough due to vast memorization and intricate systems, with Cosmology/Astrophysics being challenging for its vast scales and theoretical nature. The difficulty often lies in integrating multiple scientific fields, like the math in physics or the biological details in biochemistry.
List of Hardest Science Majors
The brain is the last and grandest biological frontier, the most complex thing we have yet discovered in our universe. It contains hundreds of billions of cells interlinked through trillions of connections.
Quantum gravity is one of the biggest unsolved and hardest physics problems in the world, exactly how gravity and the quantum will be made to coexist within the same theory.
Top 10 Toughest Courses in the World in 2026
According to study after study, Algebra 1 is highlighted as the most failed course in America. Some estimates say that as many as 40% of students take the course more than once in order to achieve an acceptable grade.
The most difficult majors require extensive study time, more STEM courses, and a solid foundation in math. Chemistry, engineering, and physics are generally considered some of the hardest college majors available to undergraduates.
Science Relies Heavily on Memorization
To understand scientific concepts, students need to be able to remember a large amount of information. This can be a challenge for people who find it difficult to retain information for long periods of time. In addition, poor note-taking skills aggravate this problem.
14 Tough Questions Answered
Grand Challenges are ambitious but achievable goals that harness science, technology, and innovation to solve important national or global problems and that have the potential to capture the public's imagination.
About 75% of your brain is water, making hydration crucial for sharp thinking, focus, and mood, as even mild dehydration (losing 2% of body water) can impair memory, concentration, and reaction time. The remaining part of the brain is mostly fat, and this water content is essential for creating neurotransmitters and supporting brain function.
Scientific knowledge is a body of statements of varying degrees of certainty — some most unsure, some nearly sure, but none absolutely certain. As a science and health journalist, I'm not an evangelist for science.
About 95% of the universe is "invisible" because it's composed of dark matter (around 27%) and dark energy (around 68%), which don't emit, absorb, or reflect light, unlike the normal matter (stars, planets, us) that makes up the visible 5%. Dark matter's presence is inferred through its gravitational pull on visible galaxies, while dark energy is a mysterious force causing the universe's accelerated expansion.
Psychology
A bachelor's in psychology ranks among the easiest majors. You can develop skills that apply to varying careers in counseling or marketing. As you complete your undergraduate psychology degree, you'll take classes such as human development, psychology theories, and research in the psychology field.
Top 20 Hardest Degrees in the World
While all science fields require some math, biology probably requires the least. There will still be math requirements, like calculus and more, but it is not as heavy as majors like chemistry and physics. If you are interested in pursuing a science major, you should be prepared to take some math courses.
"21 juicy questions" are prompts designed to spark deep, fun, or flirty conversations, covering topics like secrets, crushes, embarrassing moments, fantasies, and life regrets, with examples including "What's the most rebellious thing you've ever done?", "What's your biggest guilty pleasure?", "What's the weirdest thing you've done for a job?", and "What's your biggest sexual fantasy?". These questions help you get to know someone better, break the ice, or add spice to a relationship, depending on the context.
ChatGPT won't answer questions about illegal activities. Or rather, it won't answer questions if you want it to help you make weapons, commit fraud, or steal someone's data.
World's Hardest Questions to Answer: Ultimate List for Exams
The ∑ symbol, called sigma, is the Greek letter used in mathematics to mean “sum” — it tells you to add things up. Think of it like a recipe that says: “Start with the first number, then add the next one, then the next, and keep going until I say stop.”
Below are the 7 steps to an A* in A-Level Maths.
1. Precision Production. Only 28 students graduated in 2020-21 with a degree in Precision Production—and only 12 in 2021-22. This area of study focuses on giving students technical knowledge and skills to work on certain products such as mattresses, furniture, automobile seats, and others.
Architecture. Architecture is known as one of the degrees that leads to the highest mental burnout due to its intense studio culture, long working hours, and demanding design expectations. Students often spend nights completing models, drawings, and critiques, which can lead to stress and exhaustion.
Medicine is widely regarded as the number one hardest degree in the world due to its complex syllabus, extended duration, intense clinical training, and high-pressure exams.