Stage 1: Inflammation In the early stages of liver disease, the liver will become swollen or inflamed as the body's natural response to injury. Liver inflammation, or hepatitis, can also occur when there are more toxins in the blood than the liver is able to manage.
There are usually few symptoms in the early stages of cirrhosis. However, as your liver loses its ability to function properly, you're likely to experience a loss of appetite, nausea and itchy skin.
Acute liver failure causes fatigue, nausea, loss of appetite, discomfort on your right side, just below your ribs, and diarrhea. Acute liver failure is a serious condition.
Acute liver failure can happen in as little as 48 hours. It's important to seek medical treatment at the first signs of trouble. These signs may include fatigue, nausea, diarrhea, and discomfort in your right side, just below your ribs.
Patients with acute-on-chronic liver failure may see their livers fail over weeks to months, compared to months to years as is typical in chronic liver failure.
When liver damage progresses to an advanced stage, fluid collects in the legs, called edema, and in the abdomen, called ascites. Ascites can lead to bacterial peritonitis, a serious infection. When the liver slows or stops producing the proteins needed for blood clotting, a person will bruise or bleed easily.
Blood tests are done to determine how well your liver works. A prothrombin time test measures how long it takes your blood to clot. With acute liver failure, blood doesn't clot as quickly as it should. Imaging tests.
Your liver can keep working even if part of it is damaged or removed. But if it starts to shut down completely—a condition known as liver failure—you can survive for only a day or 2 unless you get emergency treatment.
Liver disease often fluctuates, meaning that one day you could feel well and the next be severely ill or too tired or sleepy to do anything. This makes it hard to predict and plan your life.
Pain in your liver itself can feel like a dull throbbing pain or a stabbing sensation in your right upper abdomen just under your ribs. General abdominal pain and discomfort can also be related to swelling from fluid retention and enlargement of your spleen and liver caused by cirrhosis.
It's generally not reversible, but stopping drinking alcohol immediately can prevent further damage and significantly increase your life expectancy.
Cirrhosis cannot usually be cured, but there are ways to manage the symptoms and any complications, and stop the condition getting worse.
When a patient's liver disease reaches cirrhosis, a stage when the liver damage can no longer be reversed, it becomes a terminal diagnosis. Unlike most terminal illnesses, a cure may be available for some patients through a liver transplant.
Two-thirds of patients with alcoholic cirrhosis present with decompensated disease; 15% will develop hepatocellular carcinoma. Survival rates at 5 years vary from zero to 80%; 60 to 90% of individuals die of their liver disease.
Generally, the higher your MELD score, the lower your chances are for surviving another three months. For example, if you have a MELD score of 15 or lower, you have a 95 percent chance of surviving for at least three more months. If you have a MELD score of 30, your three-month survival rate is 65 percent.
A group of blood tests called liver function tests can be used to diagnose liver disease. Other blood tests can be done to look for specific liver problems or genetic conditions. Imaging tests. An ultrasound, CT scan and MRI can show liver damage.
If cirrhosis gets worse, some of the symptoms and complications include: yellowing of the skin and whites of the eyes (jaundice) vomiting blood. itchy skin.
Ideally, the body temperature is taken either rectally or by measuring the liver temperature, which may be a more accurate reflection of the true core body temperature.
Stage 3: Cirrhosis
During this stage of disease, symptoms become more noticeable: pain and discomfort, fatigue, appetite loss, fluid retention, jaundice, and an itchy feeling around the liver. Those with cirrhosis are also more susceptible to developing liver cancer.
Cirrhosis has become irreversible. Diagnosed at stage 3, the 1-year survival rate is 80%. It's during stage 3 that a liver transplant may be recommended. There's always a risk a person's body will reject the transplant, but if accepted, 80% of transplant patients survive more than 5 years past their operation.