Mounjaro is a more effective drug than Ozempic. As demonstrated above, tirzepatide (the active ingredient in Mounjaro) leads to more clinically significant weight loss and blood sugar reductions than semaglutide (the active ingredient in Ozempic).
If you're having trouble accessing Ozempic, your healthcare provider may recommend an alternative that works in a similar way. For Type 2 diabetes, this may include Rybelsus, Trulicity, or Mounjaro. If you're taking Ozempic off-label for weight loss, Wegovy and Saxenda are two FDA-approved options.
Many people also experience weight loss, although these medications are not FDA-approved for weight loss. When it comes to choosing GLP-1 agonist medications, there are several available alternatives to Ozempic, including Bydureon (exenatide), Victoza (liraglutide), and Trulicity (dulaglutide).
Wegovy is available at a higher dosage (2.4 mg weekly) than Ozempic. Compared to 1 mg of semaglutide, more people taking 2.4 mg reported side effects in clinical trials.
Ozempic for weight loss: which is better? In a clinical trial that compared weekly use of semaglutide 1 mg and 2.4 mg, semaglutide 2.4 mg (the maximum dose of Wegovy) caused more significant weight loss than semaglutide 1 mg (the typical maintenance dose of Ozempic) (Davies, 2021; Singh, 2022).
You've hit a plateau
It's normal to eventually hit a point where your weight loss slows down, especially if you're not working on keeping or building up your muscle mass. Losing muscle along with fat slows your metabolism and can slow down your weight loss.
Although steady state levels are reached in 4 to 5 weeks, clinical effectiveness with Ozempic will vary from person to person and may take longer due to unique factors such as age, weight, amount of body fluid, additional medications you take, kidney or liver function, or your other medical conditions.
How Long Can You Stay on Ozempic (semaglutide)? A person can stay on Ozempic® so long as they are tolerating the medication and it is deemed appropriate by their treating provider. There is no specific time frame when someone should stop taking Ozempic as it is a medication that is intended for chronic (long-term) use.
Wegovy, 2.4 milligrams, is approved to treat obesity in adults. But the problem is that only Ozempic is available in Australia. With no Wegovy, it is widely agreed Ozempic is the most effective drug for people suffering complications from obesity.
And people taking Mounjaro have been shown to lose more weight than those taking Ozempic. During the same head-to-head trial mentioned above, people taking Mounjaro lost an average of 16 lbs to 25 lbs, depending on their dose. This is compared to people in the Ozempic group who lost an average of about 12 lbs.
Rybelsus is essentially Ozempic in the form of a pill rather than an injection. Ozempic and Rybelsus are made by the same manufacturer, Novo Nordisk, and have the same active ingredient, semaglutide.
Ozempic has an average rating of 5.9 out of 10 from a total of 953 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 34% reported a negative effect. Phentermine has an average rating of 8.7 out of 10 from a total of 2987 ratings on Drugs.com.
So What's the Difference Between Ozempic and Saxenda? The key difference between these two types of weight loss injection is that Ozempic is injected once a week, whereas Saxenda must be administered daily. Ozempic (Semaglutide) acts for longer, which is why it doesn't need to be taken so often.
Extra supplies of the diabetes drug Ozempic, which is highly sought after for weight loss, should arrive in Australia by July, according to the Therapeutic Goods Administration.
Some individuals may actually gain more weight after stopping an obesity drug than they initially lost, Conde-Knape added. Studies have similarly shown weight rebound in people who stop taking Ozempic.
Teresa Shepherd said she lost 90 pounds while taking an off-brand version of the drug Ozempic for around eight months. Shepherd, who lives in Florida, told " Good Morning America" she has been able to maintain her weight loss two months after stopping the medication.
Experts said they consider Ozempic and Wegovy to be lifelong medications.
As soon as someone stops taking the drug, their body fat and former appetite tend to return. Experts recommend working with a provider versed in obesity medicine to create a plan for improved lifestyle and long-term adherence to the drug.
Since it is a weight loss drug, you should not use Ozempic if you are at a maintenance weight or underweight. Ideally, you should not take Ozempic if you do not have diabetes, or if you're pregnant, breastfeeding, or planning on becoming pregnant.
Ozempic® (semaglutide): It's one of several GLP-1 medications that are best known for their ability to help patients with type 2 diabetes control blood sugar—but the drug is also effective in helping those with obesity or overweight improve their metabolic health and lose weight.
If you take too much Ozempic, you may experience nausea and/or vomiting. You may also have other stomach-related side effects, such as bloating or abdominal pain. Too much Ozempic can also lead to low blood glucose (hypoglycemia). If this happens, you may feel shaky, weak, or sweaty.
The beginning dose is 0.25 mg once a week for the first 4 weeks. This will help give your body a chance to get used to the medicine. At Week 5, your health care provider will increase the dose to 0.5 mg once a week.
Tirzepatide is the first drug that uses the action of two hormones, GLP-1 and GIP, for greater effects. It also targets the chemical signals sent from the gut to the brain, curbing cravings and thoughts of food.