Cortisol is often called the “stress hormone” because it is responsible for modulating the body's stress response, both long term and on a daily basis. When the body is not functioning as it should, cortisol can spike at the wrong time, causing sleep difficulty which leads to fatigue.
Thyroid. An overactive or underactive thyroid can often be the underlying cause of fatigue, particularly in women. This hormone controls your body's metabolic rate i.e. how food is converted to energy.
Progesterone levels begin to rise after ovulation through the end of the menstrual cycle. Symptoms of high progesterone are similar to premenstrual syndrome and can include anxiety and agitation, bloating, breast swelling and tenderness, depression, fatigue, and weight gain.
Your brain has a lot of estrogen receptors, and when estrogen declines, so does some of the regulation that it provides. For example, estrogen helps control cortisol, the stress hormone. When that regulation is weakened, the increased stress response can result in crushing fatigue.
Hot flashes, flushes, and night sweats are the most common symptoms of low estrogen. At times, blood rushes to your skin's surface. This can give you a feeling of warmth (hot flash). Your face may look flushed.
Extreme fatigue in women can be caused by high sleep debt, being out of sync with your circadian rhythm, your menstrual cycle and period, pregnancy, menopause, hormonal contraceptives, poor diet, lack of exercise, stress and anxiety, medication side effects, and medical conditions like thyroid issues or anemia.
What happens if I have too much progesterone? There are no known serious medical consequences due to the body making too much progesterone. Levels of progesterone do increase naturally in pregnancy as mentioned above. High levels of progesterone are associated with the condition congenital adrenal hyperplasia.
Your progesterone levels are usually highest in week three of your cycle. This can make you feel more tired.
Unopposed estrogen is called estrogen dominance in some medical literature. Without progesterone's balancing influence, estrogen can work overtime in your body and cause cell overgrowths, like tumors in your uterine lining.
While progesterone doesn't directly cause weight gain, it does increase your hunger levels which may make you feel like you're eating more and therefore gaining weight. But progesterone is just a small player in hormone balance and weight management.
Summary. High estrogen levels can cause symptoms such as irregular or heavy periods, weight gain, fatigue, and fibroids in females. In males, they can cause breast tissue growth, erectile dysfunction, and infertility.
The sex hormone progesterone not only triggers ovulation but also promotes sleep. It does this by stimulating your brain to produce a neurotransmitter (a chemical that has an effect on your brain) called gamma-aminobutyric acid (GABA). The more progesterone you have, the more GABA you'll produce.
Is estrogen or progesterone better? Estrogen and progesterone are both equally important for the healthy functions of the body. If they're at proper levels, these two hormones can support your optimal health and wellbeing. The only time this question may be relevant is in regards to hormonal contraception.
Answer by OB-GYN Kelsie Cabrera, DO:
Estrogen can reduce menopausal symptoms like hot flashes, night sweats and vaginal dryness. If you have a uterus, you'll likely need to take progesterone along with the estrogen. Estrogen without progesterone increases the risk of uterine cancer.
One prime example of this is that estrogen tends to put weight on the body, while that tendency is decreased with the proper amount of progesterone.
In most cases, there's a reason for the fatigue. It might be allergic rhinitis, anemia, depression, fibromyalgia, chronic kidney disease, liver disease, lung disease (COPD), a bacterial or viral infection, or some other health condition.
Medical causes – unrelenting exhaustion may be a sign of an underlying illness, such as a thyroid disorder, heart disease or diabetes. Lifestyle-related causes – alcohol or drugs or lack of regular exercise can lead to feelings of fatigue. Workplace-related causes – workplace stress can lead to feelings of fatigue.
Many cases of tiredness are due to stress, not enough sleep, poor diet and other lifestyle factors. Try these self-help tips to restore your energy levels. If you feel you're suffering from fatigue, which is an overwhelming tiredness that isn't relieved by rest and sleep, you may have an underlying medical condition.
Low progesterone can be caused by a myriad of factors . Obesity, chronic stress and a poor diet can contribute to low progesterone, but there are also other causes, including: Hypothyroidism (underactive thyroid) Hyperprolactinemia (elevated prolactin)