They include fatigue, irritability, poor memory, loss of appetite, sleep disturbances, abdominal discomfort, and weight loss. Eventually, a severe
Thiamin deficiency can cause loss of weight and appetite, confusion, memory loss, muscle weakness, and heart problems. Severe thiamin deficiency leads to a disease called beriberi with the added symptoms of tingling and numbness in the feet and hands, loss of muscle, and poor reflexes.
Beriberi is a disease in which the body does not have enough thiamine (vitamin B1).
Thiamine deficiency contributes to a number of conditions spanning from mild neurological and psychiatric symptoms (confusion, reduced memory, and sleep disturbances) to severe encephalopathy, ataxia, congestive heart failure, muscle atrophy, and even death.
Taking thiamine will start increasing your body's levels of vitamin B1 within a few hours. However, if you're taking it to treat vitamin B1 deficiency, it may take a few weeks before you start to feel better. It's important to keep taking your thiamine for as long as the doctor tells you to.
Alcohol decreases the absorption of dietary thiamine by at least 50 percent and can damage the lining of the intestinal tract, resulting in more malabsorption. Cut out caffeine. Coffee and tea, although less damaging to the intestinal tract, can wreak havoc on thiamine absorption.
Several vitamin deficiencies have been associated with anxiety and other mental health symptoms. These include: Vitamin B1 and Energy Production.
A progressive axonal sensorimotor peripheral neuropathy due to vitamin B1 (thiamine) deficiency is a part of beriberi syndrome. Atrophic skin changes are also commonly present. The neuropathic presentation of thiamine deficiency is quite varied and may precede the systemic and cognitive symptoms.
deficiencies of thiamine can impair these nerve functions not only in the brain (brain fog) but also in the gut. the autonomic nervous system and the vagus nerve, for example, directly affect motility and gut secretions (with low motility being a primary trigger for SIBO)
In a preliminary records review, Mansourian found that 10 percent of stroke patients are thiamine deficient and 50 percent are borderline deficient.
Toxicity. It is unlikely to reach a toxic level of thiamin from food sources alone. In the setting of very high intakes, the body will absorb less of the nutrient and flush out any excess amount through the urine. There is no established toxic level of thiamin.
Brewer's yeast is the food with the highest amount of vitamin B1, with 9.7 mg/100 grams.
Best Form to Take
However, lipid-soluble derivatives of thiamine, such as thiamine propyl disulfide, thiamine tetrahydrofurfuryl disulfide, and benfotiamine, are reported to be more bioavailable than water-soluble thiamine, and have been used to treat diabetic neuropathy, myalgia, and some other conditions.
Because thiamine and the thiamine–using enzymes are present in all cells of the body, it would be plausible that inadequate thiamine affects all organ systems; however, the cells of the nervous system and heart seem particularly sensitive to the effects of thiamine deficiency.
Whole blood thiamine testing is superior to currently available alternative tests for assessing thiamine status. Serum or plasma thiamine testing suffers from poor sensitivity and specificity, and less than 10% of blood thiamine is contained in plasma.
Thiamine is generally safe. Very high doses may cause stomach upset. Taking any one of the B vitamins for a long period of time can result in an imbalance of other important B vitamins. For this reason, you may want to take a B-complex vitamin, which includes all the B vitamins.
Several B vitamins aid in the sleep process. Vitamins B1 and B2 not only turn food into energy, but also produce melatonin, the sleep hormone. The production of melatonin shows that these vitamins encourage sleep.
Heavy consumption of tannin-containing or food rich in caffeine, theobromine, and theophylline (such as those present in coffee, chocolate, and tea, respectively) can inactivate thiamine, thereby compromising the thiamine status (7, 14, 15).
Prevents hair loss: “Vitamin B deficiency, including thiamine, has been associated with hair loss,” Goldenberg says. “Therefore, replacing vitamin B1 can help restore hair loss and improve hair health in general.
Thiamine (vitamin B1) is a cofactor for enzymes of central energy metabolism and its deficiency (TD) impairs oxidative phosphorylation, increases oxidative stress, and activates inflammatory processes that can lead to neurodegeneration.
Vitamin deficiencies are a common cause of paresthesias. The B vitamins — vitamin B12 and vitamin B6 — are the most common ones. Deficiencies in copper, calcium, and magnesium can also lead to tingling in your hands and feet. Most of the time, correcting the deficiency can help reverse the symptoms.
Vitamin B1 (thiamine) provides your nerves with energy to function, while vitamin B6 relieves nerve pain and transmits nerve impulses correctly. Vitamin B12 regenerates the nerves, protecting them from damage. A deficiency in vitamins B12 or B1 may be partly responsible for your nerve pain.
Meanwhile, thiamine deficiency has been suggested to be related to fatigue and sleep disturbances, even at early stages [13].
Thiamin is a water-soluble vitamin and is absorbed into the blood from the gastrointestinal tract. It then circulates in the blood and ultimately gets excreted in the urine. Small amounts of thiamin are stored in the liver, heart, kidney, and brain, but only for a short duration.