Foetor hepaticus is a feature of severe liver disease; a sweet and musty smell both on the breath and in urine. It is caused by the excretion of dimethyl disulphide and methyl mercaptan (CH3SH)2, arising from an excess of methionine.
Liver disease and certain metabolic disorders may cause musty-smelling urine.
Liver disease can lead to high levels of ammonia in your urine, causing it to have an unpleasant smell. If left untreated, liver conditions can be fatal. Always see your doctor if you notice your urine has an unusual, ammonia-like odor.
Smelling of the breath is common after having certain food or in the morning, but with people suffering from fatty liver conditions, it remains throughout the day. The breath may have a distinct sulfur and musty smell throughout the day. It is an obvious sign of fatty liver disease and should not be ignored.
Urine that contains a lot of water and few waste products has little to no odor. If urine becomes highly concentrated — a high level of waste products with little water — your urine may have a strong ammonia odor.
When you're dehydrated and your pee gets very concentrated, it can smell strongly of ammonia. If you catch a whiff of something really strong before you flush, it might also be a sign of a UTI, diabetes, a bladder infection, or metabolic diseases.
In most cases, a strong urine smell is caused by your food or is a sign that you need more fluids. If your urine smells sweet, you feel unwell, or you have other symptoms along with foul-smelling urine, though, talk to your doctor.
Liver disease
Infections and diseases of the liver can produce high ammonia levels in the urine and the accompanying pungent odor. Ammonia levels in blood and urine will increase when the liver is not working as it should. Any continued ammonia odor in urine should be checked by a doctor.
Bilirubin in urine can be an early sign of liver damage. It may even show up before you have symptoms. So, your provider may order a bilirubin in urine test if you have a high risk for liver damage or disease because of: A family history of liver disease.
Hepatorenal syndrome occurs when the kidneys stop working well in people with serious liver problems. Less urine is produced by the body, so waste products that contain nitrogen build up in the bloodstream (azotemia). The disorder occurs in up to 1 in 10 people who are in the hospital with liver failure.
Stool That Smells Like Ammonia
Your large intestine produces ammonia when it digests protein. Your liver then neutralizes the ammonia and helps the body get rid of it. Ammonia smells from your stool may signal a problem with these organs, such as liver disease.
Disorders of the liver, bile duct, or pancreas can cause cholestasis. The skin and whites of the eyes look yellow, the skin itches, urine is dark, and stools may become light-colored and smell foul.
Diabetes does not generally cause strong-smelling urine. Uncontrolled diabetes can lead to urine that smells sweet or fruity.
Smelling of the breath is common after having certain food or in the morning, but with people suffering from fatty liver conditions, it remains throughout the day. The breath may have a distinct sulfur and musty smell throughout the day. It is an obvious sign of fatty liver disease and should not be ignored.
Non-alcoholic Fatty Liver Disease is Associated with Recurrent Urinary Tract Infection in Premenopausal Women Independent of Metabolic Syndrome.
People with cirrhosis of the liver have a life expectancy of between two and 12 years. If you have early-stage cirrhosis, treatment and lifestyle changes can help you live longer. People with advanced cirrhosis of the liver have a much shorter life expectancy.
Substances that cause fetor hepaticus
Trimethylamine is also increased in many patients with cirrhosis and may contribute to the odor of the breath.
High ketone levels cause your blood to become acidic and your body odor to be fruity. In the case of liver or kidney disease, your odor may give off a bleach-like smell due to toxin buildup in your body.
Acute liver failure can happen in as little as 48 hours. It's important to seek medical treatment at the first signs of trouble. These signs may include fatigue, nausea, diarrhea, and discomfort in your right side, just below your ribs.
Urine often has a slight ammonia smell, especially first thing in the morning or when a person is dehydrated. Smelly urine can also be a sign of an infection, however, so if the smell does not go away on its own, or if additional symptoms develop, see a doctor.
This may be due to a UTI or even to dysbiosis, where harmful bacteria increase in number and take over the good bacteria in the body. The excess bacteria may change the smell or look of the urine as it sits in the bladder, which can lead to a sulfuric smell. Cystitis needs prompt medical treatment.