For these people, histamine builds up in the body and is not broken down correctly. This can trigger an immune system response resulting in symptoms such as diarrhea, shortness of breath, headaches, or skin irritation.
You can get a runny or stuffy nose. And you'll sneeze. The mucus can also bother your throat and make you cough. Histamines can make your eyes and nose itch.
Water does aid in the removal of histamines from the body as more that 95% of excess histamines are removed from the body through the urine. Drinking adequate amounts of water helps keep histamines at safe and healthy levels that your body can process efficiently.
Vitamin C is a natural antihistamine, which means it can lower histamine levels and mitigate allergic reactions and symptoms. Consume plenty of Vitamin C rich foods, like tropical fruits, citrus fruits, broccoli and cauliflower, and berries.
Vitamin C
Vitamin C boosts the immune system. It also acts as a natural antihistamine. According to a 2018 study on vitamin C in the treatment of allergies, oxidative stress plays a key role in allergic diseases. As vitamin C is a powerful antioxidant and anti-inflammatory, it may act as a treatment for allergies.
What is the most powerful natural antihistamine? Researchers haven't yet established any natural product as the “best” or “most powerful.” Natural antihistamines with the most research backing their use include stinging nettle, vitamin C, quercetin, butterbur, bromelain, and probiotics.
Histamine intolerance (HIT) is assumed to be due to a deficiency of the gastrointestinal (GI) enzyme diamine oxidase (DAO) and, therefore, the food component histamine not being degraded and/or absorbed properly within the GI tract.
I have found that histamine intolerance is often caused by a gut health issue, particularly Small Intestinal Bacterial Overgrowth (SIBO). In fact, SIBO was the culprit of my histamine intolerance. Other common contributors include Candida overgrowth, Leaky Gut, and gluten intolerance.
Magnesium is also needed to make the enzyme, DAO, which mops up histamine when it's been released, if you can't make DAO, histamine levels in the blood increase 16.
Histamine Intolerance and Anxiety & Depression:
In the brain, histamine acts as a neurotransmitter which can affect the levels of mood altering neurotransmitters such as GABA, dopamine and serotonin; causing the increased expression of anxious and depressive feelings.
Acute stress increases the histamine turnovers in the diencephalon, nucleus accumbens and striatum. Histamine regulates anterior pituitary hormones. Anxiolytic drugs also decrease brain histamine turnover. Histamine H1 receptor antagonists and H3 receptor agonists decrease the anxiety state.
The first and most powerful line of defense against ingested histamine is diamine oxidase (DAO), a histamine neutralizing enzyme secreted by intestinal epithelial cells into the gut lumen.
A blood histamine test must be collected rapidly, as soon as symptoms develop. Instead of a blood test, a histamine test performed on urine collected over a 24-hour period may be ordered instead to evaluate histamine production over a longer time frame.
Histamine works with nerves to produce itching. In food allergies it can cause vomiting and diarrhea. And it constricts muscles in the lungs, making it harder to breathe. Most worrisome is when histamine causes anaphylaxis, a severe reaction that is potentially fatal.
When your estrogen levels rise, you release more of your own histamine. Histamine then stimulates your ovaries to release more estrogen - thus setting off a vicious cycle. In addition, estrogen stops your DAO from working well. If you are intolerant to histamine, you will not tolerate your own estrogen very well.
Histamine is a chemical created in the body that is released by white blood cells into the bloodstream when the immune system is defending against a potential allergen. This release can result in an allergic reaction from allergy triggers such as pollen, mold, and certain foods.
Estrogen stimulates mast cells to release histamine and down-regulates the DAO enzyme that clears histamine.
Sandoz issued a voluntary recall of 1,023,430 units of Zyrtec (10 mg) capsules as a result of failed impurities and a specification being reported for impurity at the 21-month stability time point, according to an FDA Enforcement Report.
You can block nighttime histamine release and get a better night's sleep by taking 0.25 -1 mg of ketotifen or zaditen at night.
About diphenhydramine
It's known as a drowsy (sedating) antihistamine and is more likely to make you feel sleepy than other antihistamines.
Coffee contains histamines in low amounts, but for people who are sensitive to them, it contains plenty to get a reaction out of them. While the natural histamine content in coffee is low, some coffee processes can increase histamine levels.
Because dehydration can influence the body's natural histamine response, making sure you drink enough water can be an effective way to help keep your histamine response in check.
And this specific allergen is two-fold, making it even more complicated. You can have an oral allergy to avocados as they're high in histamines.