RPI Deficiency This is considered to be the rarest disease in the world. Ribose-5-Phosphate Isomerase (RPI), is a crucial enzyme in a metabolic process in the human body. This condition can cause muscle stiffness, seizures, and reduction of white matter in the brain.
How many people have rare diseases? According to the National Institutes of Health (NIH), there are approximately 7,000 rare diseases affecting between 25 and 30 million Americans. This equates to 1 in 10 Americans, or one on every elevator and four on every bus.
cancer. dementia, including Alzheimer's disease. advanced lung, heart, kidney and liver disease. stroke and other neurological diseases, including motor neurone disease and multiple sclerosis.
With only four diagnosed patients in 27 years, ribose-5-phosphate isomerase deficiency is considered the rarest known genetic disease.
Heart disease is the leading cause of death in both men and women.
Cardiovascular disease is the top cause of death globally.
Cancer. Cancer refers to the uncontrolled growth of abnormal cells in the body. This can affect almost any organ or tissue including lungs, breast, colon, skin and ovaries. Due to the complexity of the disease and the variety of forms it can take, developing a cure has proven difficult.
To date, the World Health Organization (WHO) has declared only 2 diseases officially eradicated: smallpox caused by variola virus (VARV) and rinderpest caused by the rinderpest virus (RPV).
Alkaptonuria. Frequency: one in one million people globally. Alkaptonuria, or “black urine disease”, is a very rare inherited disorder that prevents the body from fully breaking down two protein building blocks (amino acids) called tyrosine and phenylalanine.
Leprosy (or Hansen's disease) is considered as one of the oldest infectious diseases ever known in human history: it has been the scourge of humanity since antiquity.
Cholera, bubonic plague, smallpox, and influenza are some of the most brutal killers in human history. And outbreaks of these diseases across international borders, are properly defined as pandemic, especially smallpox, which throughout history, has killed between 300-500 million people in its 12,000 year existence.
Examples of slow virus diseases include HIV/AIDS, caused by the HIV virus, subacute sclerosing panencephalitis, the rare result of a measles virus infection, and Paget's disease of bone (osteitis deformans), which may be associated with paramyxoviruses, especially the measles virus and the human respiratory syncytial ...
Most sudden deaths are due to heart diseases, especially sudden cardiac death. Some sudden deaths are caused by epilepsy or other conditions. A typical classification subdivides sudden deaths into arrhythmic, circulatory, and non-cardiac deaths.
The deadliest disease in the world is coronary artery disease (CAD). Also known as ischemic heart disease, CAD occurs when the blood vessels that supply blood to the heart become narrowed. Untreated CAD can lead to chest pain, heart failure, and arrhythmias. Impact of CAD worldwide.
Scarlet fever, tuberculosis, mumps, measles: You may think these are deadly diseases of the past, wiped out with vaccines and antibiotics. The truth is that these diseases are still infecting people worldwide, and some have made resurgences in the U.S. Stay healthy and safe with the precautions outlined here.
An illness which is lifelong because it ends in death is a terminal illness. It is possible and not unexpected for an illness to change in definition from terminal to chronic.