We may soon see cures for rare diseases like sickle cell disease, muscular dystrophy and progeria, a rare and progressive genetic disorder that causes children to age rapidly. Further into the future, gene therapies may help treat more common conditions, like heart disease and chronic pain.
“We generally say: Several thousand diseases affect humans of which only about 500 have any U.S. Food and Drug Administration-approved treatment,” said Cindy McConnell, a spokeswoman at NIH's National Center for Advancing Translational Sciences (NCATS).
Terminal illnesses include conditions such as late stage cancer, AIDS and some forms of heart disease. Although many incurable diseases are often terminal, there are also many incurable conditions that that a person can live with all their life.
Cardiovascular disease is the top cause of death globally.
The world has successfuly eradicated two diseases: Smallpox was declared eradicated in 1980. Rinderpest was declared eradicated in 2011.
By 2030: Cancer may overtake heart disease as the #1 cause of death, killing 640,000 people each year. The number of hepatitis C-related deaths may grow by as much as 3 times. Alzheimer's disease may become the 4th leading cause of death, killing over 150,000 people a year.
Two infectious diseases have successfully been eradicated: smallpox in humans, and rinderpest in ruminants. There are four ongoing programs, targeting the human diseases poliomyelitis (polio), yaws, dracunculiasis (Guinea worm), and malaria.
Chronic diseases are long-lasting conditions that usually can be controlled but not cured. People living with chronic illnesses often must manage daily symptoms that affect their quality of life, and experience acute health problems and complications that can shorten their life expectancy.
Lifestyle diseases share risk factors similar to prolonged exposure to three modifiable lifestyle behaviours -- smoking, unhealthy diet, and physical inactivity -- and result in the development of chronic diseases, specifically heart disease, stroke, diabetes, obesity, metabolic syndrome, chronic obstructive pulmonary ...
Projected global deaths in 2030 ranged from 64.9 million under the optimistic scenario to 80.7 million under the pessimistic scenario, variations of −11% to +10% relative to the baseline projection of 73.2 million.
To date, the World Health Organization (WHO) has declared only 2 diseases officially eradicated: smallpox caused by variola virus (VARV) and rinderpest caused by the rinderpest virus (RPV).
A disease may be caused by external factors such as pathogens or by internal dysfunctions. For example, internal dysfunctions of the immune system can produce a variety of different diseases, including various forms of immunodeficiency, hypersensitivity, allergies, and autoimmune disorders.
Only a small handful of diseases can currently be eradicated—that is, permanently removed from nature. For most other human infections, eradication is not currently possible—and might never be.
By 2050, the UN estimates that up to 10 million deaths could be caused by superbugs and associated forms of antimicrobial resistance, matching the annual global death toll of cancer.
The UN estimates that around 385,000 babies are born each day around the world (140 million a year). This number will remain relatively stable in the 50 years from 2020 to 2070. From 2070 to 2100, the number will decline to around 356,000 (130 million a year).
Obesity is a complex disease that occurs when an individual's weight is higher than what is considered healthy for his or her height. Obesity affects children as well as adults. Many factors can contribute to excess weight gain including eating patterns, physical activity levels, and sleep routines.
A lack of sleep, poor diet, anxiety, or stress can often cause a person to feel sick. These factors can make a person more susceptible to infection and illness. However, always feeling sick can also signify pregnancy or chronic illness. When sick, a person may experience stomach discomfort and vomiting.
It is reported that the incidence of MAS is up to 15% among those AOSD patients and it is considered the most severe complication, with a high mortality rate ranging from 10% to 41%[9,32].