Osteoarthritis and rheumatoid arthritis can be mistaken for each other because both are characterized by swelling and inflammation. However, rheumatoid arthritis is different because in this condition, the body's immune system attacks the joints. This can happen suddenly and cause severe inflammation.
PsA is often undiagnosed and can be misdiagnosed for rheumatoid arthritis (RA) or osteoarthritis (OA), especially in a non-rheumatologic setting [7–9]. RA is a chronic inflammatory arthritis typified by pain, swelling, and stiffness of the joints, particularly symmetric small-joint synovitis of the hands and feet [10].
The most common types include osteoarthritis (OA), rheumatoid arthritis (RA), psoriatic arthritis (PsA), fibromyalgia and gout. Arthritis and related diseases can cause debilitating, life-changing pain in different ways.
Fibromyalgia often is mistaken for RA, osteoarthritis (OA), Lyme disease, chronic fatigue syndrome, underactive thyroid, depression, and lupus.
Osteoarthritis happens when cartilage in your joints wears away over time. In contrast, psoriatic arthritis is an autoimmune disease. It happens when your immune system mistakenly views healthy cells as a threat and attacks them. Psoriatic arthritis can affect your skin, nails, and joints.
“Worsening joint pain and swelling, or new or worsening psoriatic lesions, are the most common red flags that someone is having a PsA flare,” says Yamen Homsi, M.D., the section chief of rheumatology at NYU Langone Hospital in Brooklyn, NY.
The main symptoms of osteoarthritis are pain and stiffness in your joints. This can make it difficult to move the affected joints and do certain activities. The symptoms may come and go, which can be related to things like your activity levels and even the weather. In more severe cases, the symptoms can be continuous.
Rheumatoid arthritis can be one of the most painful types of arthritis; it affects joints as well as other surrounding tissues, including organs. This inflammatory, autoimmune disease attacks healthy cells by mistake, causing painful swelling in the joints, like hands, wrists and knees.
Inflammatory osteoarthritis is generally treated with nonsteroidal anti-inflammatory drugs and, very rarely, corticosteroid injections directly into the affected joints.
The difference between osteoarthritis (OA) and rheumatoid arthritis (RA) is in the way these diseases harm the body. While OA is a degenerative disease caused by a physical breakdown of the cartilage, and eventually the bones, RA is an autoimmune disease caused by a reaction in the immune system.
Primary osteoarthritis has no known cause. Secondary osteoarthritis is caused by another disease, infection, injury, or deformity. Osteoarthritis starts with the breakdown of cartilage in the joint. As the cartilage wears down, the bone ends may thicken and form bony growths (spurs).
The most common triggers of an OA flare are overdoing an activity or trauma to the joint. Other triggers can include bone spurs, stress, repetitive motions, cold weather, a change in barometric pressure, an infection or weight gain.
OA usually affects fewer joints, and its symptoms are generally limited to the joints. The progression of RA is more difficult to predict, and it can cause more widespread symptoms. The outlook for people with RA has greatly improved due to advances in research and therapies.
Lupus. Lupus, or systemic lupus erythematosus (SLE), is a chronic autoimmune disease that affects many parts of the body, including the joints, skin, blood vessels, and internal organs. Though lupus is not a form of arthritis, arthritis is one of its most common symptoms, according to the Lupus Foundation of America.
In osteoarthritis the joints may feel achy and tender, but they might not look very swollen or feel warm (the way joints affected by RA do). There may be more swelling after physical activity, and more swelling as the condition becomes more advanced.
Can an X-ray show the difference between OA and RA? Yes. Joints in RA look different than joints in OA. That's why X-rays are a helpful tool for figuring out the cause of joint pain.
NSAIDs are the most effective oral medicines for OA. They include ibuprofen (Motrin, Advil) naproxen (Aleve) and diclofenac (Voltaren, others). All work by blocking enzymes that cause pain and swelling.
People with osteoarthritis usually have joint pain and, after rest or inactivity, stiffness for a short period of time. The most commonly affected joints include the: Hands (ends of the fingers and at the base and ends of the thumbs). Knees.
SYMPTOMS: Patients with early disease experience localized joint pain that worsens with activity and is relieved by rest, while those with severe disease may have pain at rest. Weight bearing joints may “lock” or “give way” due to internal derangement that is a consequence of advanced disease.
Although there's no blood test for osteoarthritis, certain tests can help rule out other causes of joint pain, such as rheumatoid arthritis. Joint fluid analysis. Your doctor might use a needle to draw fluid from an affected joint.
Your doctor will most likely offer you a medicine called a DMARD (disease-modifying antirheumatic drug). DMARDs help calm your symptoms, may slow down the disease, and prevent or slow joint damage. Conventional DMARDs and systemic psoriasis drugs are often the first medicines prescribed. Methotrexate is common for PsA.
In the absence of a definitive diagnostic test for psoriatic arthritis (PsA), your health care provider will diagnose you by examining your skin, nails, joints and other symptoms. You may have X-rays, an MRI, an ultrasound and blood tests as well.
The skin symptoms of psoriatic arthritis include a rash, thick, red skin, or flaky, silver-white scaly patches, as in plaque psoriasis. The skin may itch and be painful. Up to 85% of people with PsA experience skin problems associated with psoriasis before having psoriatic arthritis symptoms.