There are many different types of skin-related autoimmune disorders, including scleroderma, psoriasis, dermatomyositis, epidermolysis bullosa, and bullous pemphigoid. Scleroderma.
Duke dermatologists diagnose autoimmune skin diseases like pemphigus, pemphigoid, scleroderma, morphea, dermatomyositis, dermatitis herpetiformis, vasculitis, lupus, and Sjögren's syndrome -- all of which occur when the body's immune system attacks healthy skin or tissue.
Pemphigus is a rare group of autoimmune diseases that causes blisters on the skin and mucous membranes throughout the body. It can affect the mouth, nose, throat, eyes, and genitals.
Autoimmune disease happens when the body's natural defense system can't tell the difference between your own cells and foreign cells, causing the body to mistakenly attack normal cells.
Asherson's syndrome is an extremely rare autoimmune disorder characterized by the development, over a period of hours, days or weeks, of rapidly progressive blood clots affecting multiple organ systems of the body.
Your body works to protect the wound by sending nutrient-rich blood to the injury to help regenerate new skin. This healing process depends on healthy immune cells. But if your immune system is sluggish, your skin can't regenerate. Instead, your wounds linger and have a hard time healing.
Dermatomyositis (dur-muh-toe-my-uh-SY-tis) is an uncommon inflammatory disease marked by muscle weakness and a distinctive skin rash. The condition can affect adults and children. In adults, dermatomyositis usually occurs in the late 40s to early 60s. In children, it most often appears between 5 and 15 years of age.
A biopsy is usually needed for a definitive diagnosis of autoimmune skin disease, although a characteristic appearance may be suggestive of a particular condition [9]. Blood tests may include: Tests for circulating skin autoantibodies (indirect immunofluorescence) [14]
Scleroderma is an autoimmune connective tissue and rheumatic disease that causes inflammation in the skin and other areas of the body. When an immune response tricks tissues into thinking they are injured, it causes inflammation, and the body makes too much collagen, leading to scleroderma.
Many people with lupus experience a red or purplish rash that extends from the bridge of the nose over to the cheeks in a shape that resembles that of a butterfly. The rash may be smooth, or it may have a scaly or bumpy texture. It can look like a sunburn.
Like systemic lupus, cutaneous lupus is caused by an autoimmune response, meaning the body attacks its own tissues and organs. In cutaneous lupus, the immune system targets skin cells, causing inflammation that leads to red, thick, and often scaly rashes and sores that may burn or itch.
The flaking and itchy skin caused by eczema, seborrheic dermatitis, and psoriasis can be very uncomfortable and often leads to feeling self-conscious or alone during flare-ups.
If you develop a purple-to-red rash that does not lighten, or blanch, with pressure, ulcerations of the skin, or a purple net pattern on your skin, this should prompt you to see a dermatologist for evaluation.
People with Sjogren's may be more susceptible to a rash, especially after spending time in the sun. Skin problems that occur with the condition may present as: xerosis, or dry, rough skin. small “blood spots” or purpura on the lower legs due to vasculitis, or inflammation of the blood vessels.
Some common autoimmune diseases, including Type 1 diabetes mellitus, are relatively easy to diagnose, while others, such as vasculitis, Addison's disease, lupus, and other rheumatic diseases, are more difficult.
Background: Autoimmune diseases are multifactorial with environmental and heritable factors. Autoimmunity reflects an altered immune status, therefore the presence of more than one disorder is not uncommon. The coexistence of three or more autoimmune diseases in a patient constitutes multiple autoimmune syndrome (MAS).
Around 25% of patients with an autoimmune disease tend to develop additional autoimmune diseases (6). A number of factors have been thought to contribute to the development of multiple autoimmune diseases.
Melanoma – Nearly 80% of skin cancer-related deaths are caused by melanoma. People who develop melanoma often notice sores that don't heal, areas of darker pigmentation spreading out from a mole, or quickly growing or changing spots.