What autoimmune disease causes an itchy rash? Some autoimmune diseases that may cause an itchy rash are cutaneous lupus, oral lichen planus, and erythrodermic psoriasis.
Like systemic lupus, cutaneous lupus is caused by an autoimmune response, meaning the body attacks its own tissues and organs. In cutaneous lupus, the immune system targets skin cells, causing inflammation that leads to red, thick, and often scaly rashes and sores that may burn or itch.
Scleroderma and its Effects on Skin
Scleroderma (also called systemic sclerosis), which causes the skin to thicken to a debilitating degree, has the highest mortality of any autoimmune disease: People with diffuse scleroderma (a subtype) have an average survival rate of only 10 years.
Asherson's syndrome is an extremely rare autoimmune disorder characterized by the development, over a period of hours, days or weeks, of rapidly progressive blood clots affecting multiple organ systems of the body.
The exact cause of autoimmune disorders is unknown. One theory is that some microorganisms (such as bacteria or viruses) or drugs may trigger changes that confuse the immune system. This may happen more often in people who have genes that make them more prone to autoimmune disorders.
Itching is a symptom of many health conditions. Some common causes are: Allergic reactions to food, insect bites, pollen, and medicines. Skin conditions such as eczema, psoriasis, and dry skin.
Examples include dry skin (xerosis), eczema (dermatitis), psoriasis, scabies, parasites, burns, scars, insect bites and hives. Internal diseases. Itching on the whole body might be a symptom of an underlying illness, such as liver disease, kidney disease, anemia, diabetes, thyroid problems and certain cancers.
If this system is not functioning well, certain cytokines can be expressed abnormally. In your case, it would appear that when you get a bit run down and as your immune system weakens, you have a tendency to histamines and it is this substance that causes you to itch.
Sometimes an illness can trigger the nervous system to make the skin itch even when there's nothing there to cause a rash. This can cause skin irritation when a person has been scratching a lot. Causes of this type of itching include stroke, multiple sclerosis, nerve damage, and shingles.
Itching and rashes often occur together, but itchy skin alone can happen with dry skin, bug bites, some health conditions, or as a reaction to certain medications. The causes of skin itching, or pruritis, are usually harmless. They are often temporary issues such as dry skin or a bug bite.
What Is Pemphigus? This is a rare autoimmune skin disorder that occurs when your immune system starts attacking healthy epidermis cells (the top layer of your skin). Pemphigus can manifest itself as blisters and sores on your skin or mucous membranes of the body like your mouth, eyes, nose, throat, and genitals.
Systemic sodium channel blockers, such as carbamazepine and oxcarbazepine are the first-line choice, as they calm the ectopic neuronal firing. Gabapentin and pregabalin are commonly prescribed for patients with brachioradial pruritus and appear effective at similar concentrations as used for neuropathic pain.
Itching is often triggered by histamine, a chemical in the body associated with immune responses. It causes the itch and redness you see with insect bites, rashes and skin dryness or damage. Histamine is released by the body during allergic reactions, such as those to pollen, food, latex and medications.
Itching with kidney disease can be generalized, or it can occur in specific parts of the body. Common areas for this type of itching include the head, arms, back, and abdomen. It also tends to be worse at night, which can disturb your sleep.
What does diabetes itching feel like? If you have diabetes, itching can be intense. It's an irritating feeling that makes it hard not to scratch, but scratching can make the itch worse. You can itch anywhere, but if you have nerve damage (neuropathy) associated with diabetes, your lower legs may itch.
Disease Overview
Prurigo nodularis (PN) is a chronic inflammatory skin disease where an extremely itchy, symmetrically distributed rash appears most commonly on the arms, legs, the upper back and/or the abdomen. The itch associated with PN is so severe that it often interferes with sleep and psychological wellbeing.
Neuropathic itch is one presentation of neuropathic pain. Neuropathic pain can cause discomfort that presents many ways, such as: A sensation of burning or freezing. Tingling or "electric shock" feeling.
Antinuclear antibodies are markers for a number of autoimmune diseases, the most notable of which is systemic lupus erythematosus (Ferrell and Tan, 1985). Antibodies to specific nuclear constituents are high specific for certain collagen vascular diseases.