RPI Deficiency This is considered to be the rarest disease in the world. Ribose-5-Phosphate Isomerase (RPI), is a crucial enzyme in a metabolic process in the human body. This condition can cause muscle stiffness, seizures, and reduction of white matter in the brain.
cancer. dementia, including Alzheimer's disease. advanced lung, heart, kidney and liver disease. stroke and other neurological diseases, including motor neurone disease and multiple sclerosis.
According to the National Institutes of Health (NIH), there are approximately 7,000 rare diseases affecting between 25 and 30 million Americans. This equates to 1 in 10 Americans, or one on every elevator and four on every bus. What are some examples of rare diseases?
Leading causes of death globally
The world's biggest killer is ischaemic heart disease, responsible for 16% of the world's total deaths. Since 2000, the largest increase in deaths has been for this disease, rising by more than 2 million to 8.9 million deaths in 2019.
Cancer. Cancer refers to the uncontrolled growth of abnormal cells in the body. This can affect almost any organ or tissue including lungs, breast, colon, skin and ovaries. Due to the complexity of the disease and the variety of forms it can take, developing a cure has proven difficult.
Of great importance to public and child health are the vaccines against the so-called six killer diseases of childhood-measles, pertussis, diphtheria, tetanus, tuberculosis and poliomyelitis.
Cholera, bubonic plague, smallpox, and influenza are some of the most brutal killers in human history. And outbreaks of these diseases across international borders, are properly defined as pandemic, especially smallpox, which throughout history, has killed between 300-500 million people in its 12,000 year existence.
Sepsis happens when an infection you already have triggers a chain reaction throughout your body. Infections that lead to sepsis most often start in the lung, urinary tract, skin, or gastrointestinal tract. Without timely treatment, sepsis can rapidly lead to tissue damage, organ failure, and death.
Rabies is a vaccine-preventable, zoonotic, viral disease affecting the central nervous system. Once clinical symptoms appear, rabies is virtually 100% fatal.
Examples of slow virus diseases include HIV/AIDS, caused by the HIV virus, subacute sclerosing panencephalitis, the rare result of a measles virus infection, and Paget's disease of bone (osteitis deformans), which may be associated with paramyxoviruses, especially the measles virus and the human respiratory syncytial ...
Most sudden deaths are due to heart diseases, especially sudden cardiac death. Some sudden deaths are caused by epilepsy or other conditions. A typical classification subdivides sudden deaths into arrhythmic, circulatory, and non-cardiac deaths.
The deadliest disease in the world is coronary artery disease (CAD). Also known as ischemic heart disease, CAD occurs when the blood vessels that supply blood to the heart become narrowed. Untreated CAD can lead to chest pain, heart failure, and arrhythmias. Impact of CAD worldwide.
But both Hitler and Stalin were outdone by Mao Zedong. From 1958 to 1962, his Great Leap Forward policy led to the deaths of up to 45 million people—easily making it the biggest episode of mass murder ever recorded.
The most distinctive feature of this viral family is genome size: coronaviruses have the largest genomes among all RNA viruses, including those RNA viruses with segmented genomes.
So were they ever alive? Most biologists say no. Viruses are not made out of cells, they can't keep themselves in a stable state, they don't grow, and they can't make their own energy. Even though they definitely replicate and adapt to their environment, viruses are more like androids than real living organisms.
Cardiovascular disease is the top cause of death globally. In the map we see death rates from cardiovascular diseases across the world.