Some signs of leukemia, like night sweats, fever, fatigue and achiness, resemble flu-like symptoms. Unlike symptoms of the flu, which generally subside as patients get better, leukemia symptoms generally last longer than two weeks, and may include sudden weight loss, bone and joint pain and easy bleeding or bruising.
Common leukemia signs and symptoms include: Fever or chills. Persistent fatigue, weakness. Frequent or severe infections.
Complete blood count (CBC): This blood test lets your healthcare provider know if you have abnormal levels of red blood cells, white blood cells and platelets. If you have leukemia, you'll likely have higher than normal counts of white blood cells.
When is a patient tested for leukemia? "A patient may be tested for leukemia if he or she has unexplained weight loss, night sweats or fatigue, or if he or she bruises or bleeds easily," Dr. Siddon says. "Sometimes routine blood work shows an unexplained elevated number of white blood cells."
Your doctor will conduct a complete blood count (CBC) to determine if you have leukemia. This test may reveal if you have leukemic cells. Abnormal levels of white blood cells and abnormally low red blood cell or platelet counts can also indicate leukemia.
Chronic Leukemia May Go Undetected
It may take months or even several years before the disease begins to cause symptoms that alert the patient that something is wrong.
Leukemia can produce a variety of symptoms, although most are not often apparent in the earliest stages of the malignancy. The most common symptoms of leukemia—fatigue, pale skin, weight loss and night sweats—are often attributed to other less serious conditions, such as the flu.
Stage 1 – A patient has high levels of white blood cells and enlarged lymph nodes. Stage 2 – A patient has high levels of white blood cells and is anemic. He or she may also have enlarged lymph nodes. Stage 3 – A patient has high levels of white blood cells and is anemic.
Leukemia starts in the soft, inner part of the bones (bone marrow), but often moves quickly into the blood. It can then spread to other parts of the body, such as the lymph nodes, spleen, liver, central nervous system and other organs.
Laboratory Findings and Diagnosis. If leukemia is suspected, a complete blood count should be obtained. Marked leukocytosis, often greater than 100,000 white blood cells per μL (100.0 × 109 per L), is the hallmark laboratory finding in chronic myelogenous leukemia and chronic lymphocytic leukemia.
Bone marrow biopsy
This is the gold standard investigation to diagnose Leukemia. This invasive procedure is done after the suspicion of Leukemia or when the blood test reports point to a Leukemic picture. The procedure involves the removal of a small sample of bone marrow from the hipbone.
Often referred to as a “silent disease,” CLL can be difficult to diagnose, because people often don't have any symptoms until later in the disease, and others have symptoms that resemble signs of other conditions, such as a cold.
Infections and Fevers
Your blood cells help your immune system function. When these cells are unhealthy, your body's immune system can't function normally causing you to get sick more often. One of the most common first symptoms of leukemia is frequent fevers and infection.
During the progression of leukemia, white blood cells (neoplastic leukocytes) found in bone marrow may begin to filter into the layers of the skin, resulting in skin lesions. “It looks like red-brown to purple firm bumps or nodules and represents the leukemia cells depositing in the skin,” Forrestel says.
Blood tests are essential to accurate diagnosis of this complex disease. These tests can show whether you have leukemia cells or abnormal levels of normal cells: Blood smear: With this test, we take a drop of blood and look at it under a microscope.
Chronic leukemia often causes only a few symptoms or none at all. Signs and symptoms usually develop gradually. People with a chronic leukemia often complain that they just do not feel well. The disease is often found during a routine blood test.
Here is a list of some symptoms you might have if you have cancer related fatigue: lack of energy – you may just want to stay in bed all day. feeling you just cannot be bothered to do much. sleeping problems such as unable to sleep or disturbed sleep.
Some signs of leukemia, like night sweats, fever, fatigue and achiness, resemble flu-like symptoms. Unlike symptoms of the flu, which generally subside as patients get better, leukemia symptoms generally last longer than two weeks, and may include sudden weight loss, bone and joint pain and easy bleeding or bruising.
Many people with chronic lymphocytic leukaemia (CLL) won't have any symptoms at all. They are diagnosed because they have a routine blood test for something else. In CLL symptoms tend to be mild at first and get worse slowly. Many symptoms are vague.
If caught early, leukemia can be cured by undergoing several cancer treatments.
Myelodysplastic syndrome refers to a group of related disorders in which abnormal blood-forming cells develop in the bone marrow. At first, these cells interfere with the production of normal blood cells. Later, these cells may become cancerous, turning into a form of leukemia .
The median age of a patient diagnosed with acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL) or chronic myeloid leukemia (CML) is 65 years and older. However, most cases of acute lymphocytic leukemia (ALL) occur in people under 20 years old. The median age of an ALL patient at diagnosis is 15.