Is zoledronic a chemo drug?

Zoledronic acid (Zometa) is not cancer chemotherapy, and it will not slow or stop the spread of cancer. However, it can be used to treat bone disease

bone disease
Bone diseases can make bones easy to break. Different kinds of bone problems include: Low bone density and osteoporosis, which make your bones weak and more likely to break. Osteogenesis imperfecta makes your bones brittle.
https://medlineplus.gov › bonediseases
in patients who have cancer. Zoledronic acid is in a class of medications called bisphosphonates.

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What type of cancer is zoledronic acid?

What is zoledronic acid? Zoledronic acid is a drug that's given to reduce the risk of breast cancer spreading to the bones and other parts of the body. It belongs to a group of drugs called bisphosphonates. These drugs slow down or prevent bone damage.

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What type of treatment is zoledronic acid?

Zoledronic acid injection is used to treat hypercalcemia (high levels of calcium in the blood) that may occur in patients with some types of cancer.

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What is the most common side effect of zoledronic acid?

Fever is the most common adverse effect associated with zoledronic acid infusion. Flu-like syndromes including fever, chills, bone pain, and/or arthralgias and myalgias have also occasionally been reported. These symptoms generally did not require treatment and resolved within 24 to 48 hours.

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Does zoledronic acid weaken the immune system?

3.5. Effects of ZOL on anti-cancer immunity. In addition to its effects on bone cells, ZOL has profound effects on the immune system, including a plethora of immune cell subsets expressing the mevalonate pathway enzymes, leading to a general increase in anti-tumour immunity [65].

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Bone metastases: Role of zoledronic acid, denosumab and other strategies

15 related questions found

How do you feel after zoledronic acid?

More common
  1. Abdominal or stomach pain.
  2. back pain.
  3. bad, unusual, or unpleasant (after) taste.
  4. bladder pain.
  5. blistering, crusting, irritation, itching, or reddening of the skin.
  6. bone pain.
  7. burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings.
  8. change in taste.

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How does zoledronic acid make you feel?

The majority of the side effects, such as fever and chills, pain in the muscles or joints, and headache, occur within the first three days following the dose of Zoledronic acid 5 mg. The symptoms are usually mild to moderate and go away within three days.

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Who should not take zoledronic acid?

You should not be treated with zoledronic acid if you are allergic to it. You also should not receive Reclast if you have: low levels of calcium in your blood (hypocalcemia); or. severe kidney disease.

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Does walking increase bone density?

Weight-bearing exercises, such as walking, jogging, and climbing stairs, can help you build strong bones and slow bone loss.

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Can zoledronic acid make you gain weight?

Tell your doctor right away if you have agitation, blood in the urine, confusion, decreased urine output, depression, dizziness, headache, irritability, lethargy, muscle twitching, nausea, rapid weight gain, seizures, stupor, swelling of the face, ankles, or hands, or unusual tiredness or weakness.

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Does Medicare cover zoledronic acid infusion?

Medicare Part A or Medicare Part B will pay for a portion of the cost of osteoporosis medications delivered intravenously or by injection. These medications may include ibandronate (Boniva), zoledronic acid (Reclast), denosumab (Prolia) and sometimes calcitonin (Miacalcin).

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How long does zoledronic acid stay in your body?

Zoledronic acid medication is a long-acting drug. As such, it stays in your body longer than 12 months (probably more than 24 months). Therefore, delaying your treatment for a number of months will not put you at a higher risk of sustaining fragility fracture nor cause significant decline in your bone mineral density.

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Which is better prolia or zoledronic acid?

In one comparative study of zoledronic acid and denosumab, denosumab showed a greater increase in spinal bone mass density (BMD) compared to zoledronic acid. Zoledronic acid also showed a greater incidence of flu-like symptoms. Based on this study, Prolia may be more effective for certain people.

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Is zoledronic acid worth having?

User Reviews for Zoledronic acid to treat Prevention of Osteoporosis. Zoledronic acid has an average rating of 4.4 out of 10 from a total of 42 ratings for the treatment of Prevention of Osteoporosis. 31% of reviewers reported a positive experience, while 55% reported a negative experience.

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What happens when you stop taking zoledronic acid?

Discontinuation of therapy should be considered by doctors after 3 to 5 years in patients with osteoporosis at low risk of fracture. Patients who discontinue therapy should have their risk for fracture re-evaluated periodically.

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How quickly does zoledronic acid work?

It can take 2 to 3 months before you notice the full effects. If you are having zoledronic acid to lower calcium levels in your blood, it is usually given as a single dose.

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Which fruit is best for bones?

Fruits
  • Blackberries.
  • Blueberries.
  • Figs, dried, uncooked.
  • Grapes.
  • Kiwi fruit, fresh, raw.
  • Mulberries.
  • Plums, dried (prunes)
  • Pomegranate juice.

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What is the best exercise for osteoporosis?

Weight-bearing aerobic activities

Examples include walking, dancing, low-impact aerobics, elliptical training machines, stair climbing and gardening. These types of exercise work directly on the bones in your legs, hips and lower spine to slow mineral loss.

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What is the best exercise for bone density?

Weight-bearing and resistance exercises are the best for your bones. Weight-bearing exercises force you to work against gravity. They include walking, hiking, jogging, climbing stairs, playing tennis, and dancing. Resistance exercises – such as lifting weights – can also strengthen bones.

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Does zoledronic acid affect your teeth?

If you are having dental procedures while receiving this medicine, you may have an increased chance of having a severe problem with your jaw. Make sure you tell your doctor or dentist about any new problems, such as pain or swelling, with your teeth or jaw.

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What is the safest infusion for osteoporosis?

Zoledronic acid is given once a year as an intravenous (IV) infusion to treat osteoporosis. It is also given every two years as an IV infusion to prevent osteoporosis. Zoledronic acid increases bone density and reduces the incidence of the spine and non-spine fractures, including hip fractures.

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Why is zoledronic acid given once a year?

The results of this trial indicate that a once-yearly infusion of zoledronic acid during a 3-year period significantly reduces the risk of vertebral, hip, and other fractures in patients with postmenopausal osteoporosis.

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Can you drink alcohol with zoledronic acid?

Check with your doctor or pharmacist before you start or stop taking any other drugs. The drinking of alcohol (in small amounts) does not appear to affect the safety or usefulness of zoledronic acid. pregnancy. It is best to use birth control while being treated with zoledronic acid.

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What is the cost of zoledronic acid infusion?

The cost for zoledronic acid intravenous solution (4 mg/5 mL) is around $46 for a supply of 5 milliliters, depending on the pharmacy you visit.

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Can zoledronic acid reverse osteoporosis?

Zoledronate (zoledronic acid) Zoledronate is an osteoporosis medication that can help strengthen your bones and reduce your risk of breaking a bone. It is available as an annual intravenous infusion (drip). Zoledronate is a 'bisphosphonate' – a group of drugs that work by slowing down the cells that break down bone.

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