Some key drugs that interact with steroids include anticoagulants (such as warfarin), drugs for blood pressure, antiepileptics, antidiabetic drugs, antifungal drugs, bronchodilators (such as salbutamol) and diuretics.
Some products that may interact with this drug include: aldesleukin, mifepristone, drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, "blood thinners" such as dabigatran/warfarin, NSAIDs such as aspirin/celecoxib/ibuprofen).
It's best to avoid drinking alcohol while taking prednisone or other corticosteroids (“steroids”). Alcohol can make some steroid side effects worse. It can also sometimes worsen the underlying condition being treated. On their own, steroids, like prednisone, and alcohol can suppress your immune system.
Prednisone may decrease your ability to fight infection and can prevent you from developing symptoms if you get an infection. Stay away from people who are sick and wash your hands often while you are taking this medication. Be sure to avoid people who have chicken pox or measles.
But there are steps you can take to decrease the risk of unwanted side effects. Things to avoid (or cut back on) while taking prednisone include: Caffeine: Caffeine can add to the unwanted stimulant effects of prednisone. Combining caffeine with steroids can keep you awake at night or make you feel jittery and anxious.
Steroids may increase your risk of developing ulcers or gastrointestinal bleeding, especially if you take these medications along with non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen or aspirin. If at all possible, don't combine steroids with NSAIDs.
Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose). This medicine may cause stomach bleeding. Daily use of alcohol while using this medicine may increase your risk for stomach bleeding. Limit alcoholic beverages.
Also, increase your intake of low-fat foods that have high calcium levels. Some of these include corn, sardines, almonds, broccoli, milk, yogurt, cheese, tofu, cooked soybeans, boiled white beans, and salmon.
Sometimes a person will think that fluid retention is akin to weight gain. Fluid retention can cause weight gain but as steroids are reduced, fluids will usually reduce as well, along with some of the weight gain. Drinking plenty of water and exercising can help with fluid retention.
The fear of using corticosteroids is so common that it has its own name: corticophobia. For topical steroids, this fear stems from well-known and severe adverse effects like Cushing syndrome and permanent skin atrophy.
Prednisone generally works very quickly — usually within one to four days — if the prescribed dose is adequate to reduce your particular level of inflammation.
A gradual reduction in prednisone dosage gives your adrenal glands time to resume their usual function. The amount of time it takes to taper off prednisone depends on the disease being treated, the dose and duration of use, and other medical considerations. A full recovery can take a week to several months.
The most serious prednisone side effects usually include allergic reactions, infections, gastrointestinal issues and elevated blood sugar. These may occur when people take larger doses or take the medication for long-term treatment.
The risk or severity of adverse effects can be increased when Prednisolone is combined with Brodalumab. The risk or severity of hyperglycemia can be increased when Prednisolone is combined with Bromocriptine. The risk or severity of adverse effects can be increased when Prednisolone is combined with Budesonide.
Official answer. There is a moderate interaction between Ibuprofen and prednisone. It should only used together on the instruction of a Doctor, and needs to be used with caution together especially if you are prone to stomach upset including stomach ulcers and bleeding.
If symptoms such as abdominal pain, fever or unusual digestive problems (diarrhea, constipation) occur during corticosteroid therapy, notify your physician.
Take prednisolone with breakfast so it does not upset your stomach. Taking prednisolone in the morning also means it's less likely to affect your sleep. If your prednisolone tablets are labelled as "enteric coated" or "gastro resistant", you can take these with or without food but make sure to swallow them whole.
Short-term courses of prednisone appear to have less effect on weight. So if you're taking prednisone for around 10 days or less, you're not as likely to have weight gain.
Teas that can cause problems
Because corticosteroids rely on their immunosuppressant properties for healing, it's counterproductive to drink a tea made from an immunostimulant herb, such as Echinacea. Herbal teas that can make Prednisone less effective include cat's claw, astragalus and licorice root.
“If corticosteroids are to blame, gradually tapering off them can help with weight loss and facial swelling,” Dr. Guo said. “You'll take less and less until your body adjusts, and you might be able to safely stop the steroid. You need to have normal adrenal gland function before you stop long-term steroids.”
Prednisone does not usually cause sleepiness but may make you feel dizzy, irritable with mood swings, or cause you to have trouble sleeping (insomnia). If your dose is stopped too quickly or if you take prednisone for a long period of time you may feel severely fatigued.
Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance for unwanted effects. Take this medicine with food or milk to avoid stomach irritation.
Interactions between your drugs
No interactions were found between prednisone and Vitamin D3.