Other GLP-1 agonists that are alternatives to Ozempic include Byetta, Victoza, Tanzeum, Trulicity, and Mounjaro.
Rybelsus contains the same medication as Ozempic, but in oral form. It's also FDA approved to treat Type 2 diabetes in adults when added to a healthy diet and exercise.
Ozempic stimulates the release of insulin and lowers blood sugar. When you abruptly stop using it, the amount of glucose in your body can spike, especially if you have diabetes. Some may end up in the ER due to sheer exhaustion from the blood sugar spikes and crashes.
How Long Can You Stay on Ozempic (semaglutide)? A person can stay on Ozempic® so long as they are tolerating the medication and it is deemed appropriate by their treating provider. There is no specific time frame when someone should stop taking Ozempic as it is a medication that is intended for chronic (long-term) use.
Metformin is a widely used first-line medication for treating type 2 diabetes and can also be considered a lower-cost alternative to semaglutide (Ozempic).
Both Saxenda and Ozempic are injectable medications used with diet and exercise. Ozempic is intended for people with type 2 diabetes, and Saxenda helps people with overweight or obesity manage weight loss. They are both GLP-1 agonists that help maintain blood sugar levels and curb appetite.
Medicare doesn't cover Ozempic (or Wegovy) for weight loss
That means unless you have another source of coverage, you'd need to pay out of pocket for a semaglutide prescription for weight loss, whether it's branded Ozempic or Wegovy.
For most people, stopping Ozempic cold turkey is not recommended. When to stop Ozempic is an individual decision you should come to with the help of your healthcare provider. If your health provider agrees it's time to stop taking Ozempic, they will provide you with instructions for tapering off your dose.
Ozempic for weight loss: which is better? In a clinical trial that compared weekly use of semaglutide 1 mg and 2.4 mg, semaglutide 2.4 mg (the maximum dose of Wegovy) caused more significant weight loss than semaglutide 1 mg (the typical maintenance dose of Ozempic) (Davies, 2021; Singh, 2022).
If you don't have diabetes, taking Ozempic for weight loss is considered an off-label use. Wegovy, a higher-dose version of Ozempic, is approved to help people manage their weight. This includes adults and adolescents ages 12 and older who meet certain body mass index (BMI) criteria.
Saxenda is an approved weight loss medication, and is readily available in Australia. Cost is approximately $387 a month. The knock on effect from the Ozempic shortage, is that Trulicity which is manufactured by Ely-Lilly is now in short supply.
On the PBS, Ozempic costs Australians about $42 a month (four weekly injections). On a private prescription, the cost is about $132 a month.
Ozempic® is more effective for weight loss and blood sugar improvements than Saxenda®. Studies have also shown that Ozempic® leads to fewer side effects and adverse events than Saxenda® with people tolerating Ozempic® better.
You've hit a plateau
It's normal to eventually hit a point where your weight loss slows down, especially if you're not working on keeping or building up your muscle mass. Losing muscle along with fat slows your metabolism and can slow down your weight loss.
So, on average, with the recommended starting Ozempic dose of 0.25 mg, a 500 to 1000 calorie reduced diet, and exercise 3 times a week, you can expect to lose 3-5 pounds in the first month of treatment, which works out to about 3% of body weight for most overweight or obese individuals.
If you have private or commercial insurance, such as insurance you receive through an employer, you may be eligible to pay as little as $25 for a 1-, 2-, or 3-month prescription (maximum savings of $150 per 1-month prescription, $300 per 2-month prescription, or $450 per 3-month prescription).
Ozempic was eligible for patent challenges on December 5, 2021. By analyzing the patents and regulatory protections it appears that the earliest date for generic entry will be December 5, 2031. This may change due to patent challenges or generic licensing.
Some individuals may actually gain more weight after stopping an obesity drug than they initially lost, Conde-Knape added. Studies have similarly shown weight rebound in people who stop taking Ozempic.
Teresa Shepherd said she lost 90 pounds while taking an off-brand version of the drug Ozempic for around eight months. Shepherd, who lives in Florida, told " Good Morning America" she has been able to maintain her weight loss two months after stopping the medication.
You start feeling those usual hunger pangs again, and consequently, you may start eating more to satisfy that hunger. An increase in your consumption can lead to the regaining of weight that was lost. A 2022 study found that most individuals gain weight back a year after stopping the medication.
Extra supplies of the diabetes drug Ozempic, which is highly sought after for weight loss, should arrive in Australia by July, according to the Therapeutic Goods Administration.