Yes, Simparica and Simparica Trio are different: Simparica protects against fleas and ticks, while Simparica Trio offers broader, all-in-one monthly protection, adding prevention and treatment for heartworm, roundworms, and hookworms in addition to fleas and ticks, making it a more comprehensive internal and external parasite treatment. The main difference lies in the added ingredients in Trio (moxidectin and pyrantel) for internal parasites, compared to Simparica's single ingredient (sarolaner) for fleas/ticks.
What's the difference between Simparica and Simparica Trio? Both products provide monthly protection against Fleas, Ticks, Mites & Mange. Simparica Trio provides additional parasite proptection. This covers heartworm and intestinal worms (heartworms and hookworms), giving you a simple all-in-one monthly treatment.
Simparica Chewables and Simparica Trio - IMPORTANT SAFETY INFORMATION: Simparica Chewables is for use in dogs 6 months of age and older. Simparica Trio is for use in dogs 8 weeks of age and older. Use with caution in dogs with a history of seizures.
Simparica is a flea and tick medication formulated for dogs and can be toxic to cats. Symptoms of ingestion include vomiting, lethargy, drooling, or tremors. Immediate veterinary consultation is crucial. Treatment may involve inducing vomiting, activated charcoal administration, and supportive care such as IV fluids.
Simparica Trio is the #1 Vet Prescribed Combo Preventative
Treats and controls roundworms and hookworms.
Use with caution in dogs that have a history of neurologic (nerve or brain) disease, including a history of seizures or epilepsy. Do not use Simparica products in dogs below the minimum age or weight on the product label. Use them with caution in older, weak, or frail dogs.
Nexgard eliminates 100% existing flea within just 24 hours. On the other hand, Simparica begins to eliminate adult fleas in just 3 hours and ticks in just 8 hours.
What will my veterinarian recommend for flea and tick treatment? Veterinarians may recommend Simparica Trio, a monthly chewable tablet that prevents against heartworm, fleas, ticks, and intestinal parasites. Revolution Plus and Bravecto are also commonly recommended treatments.
The active ingredients, such as pyrethrins, pyrethroids, and organophosphates, are designed to kill fleas but can be harmful to pets if they are exposed to too much of them. Flea control product toxicity is rare but can occur, especially when a product intended for dogs is used on a cat.
Simparica kills both fleas and ticks, while Frontline Plus is effective against fleas, ticks, flea eggs and larvae and lice. Simparica kills fleas within 3 hours and kills ticks within 8 hours. Frontline Plus kills fleas within 12 hours and ticks within 48.
The best prescription alternatives to Simparica Trio include NexGard PLUS, Interceptor Plus with Bravecto or NexGard, and Credelio Quattro. These are made by trusted veterinary pharmaceutical companies like Boehringer Ingelheim, Elanco, Zoetis, and Virbac.
Paplawsky added: “You could buy three years worth of Simparica Trio for the same cost as treating adult heartworms.” Considering that heartworm prevention is only one of four forms of prevention Simparica Trio offers, while also killing fleas and ticks and treating and controlling intestinal parasites, it's easy to see ...
There are several oral prescription flea and tick medications that are safe for dogs. These preventatives come in pill and chew forms. Your vet can help you find the right one for your pup's age. Credelio Quattro is an excellent choice for flea and tick protection.
You can completely eliminate a flea infestation at a specific point in time, but fleas can always find their way back if your pet is unprotected. With consistent treatment, proper cleaning, and preventative care, you can keep your home flea-free and stop minor issues from turning into full-blown infestations.
Perhaps the most notable difference between these medications is that they contain different active ingredients. Iverhart Plus contains Pyrantel Pamoate and Ivermectin, and Simparica Trio offers a trio of ingredients - Pyrantel, Moxidectin, and Saroloner.
Both products are safe for dogs when following directions and have been approved by the FDA to treat and prevent flea and tick infestations. However, unlike Bravecto, Simparica has yet to be approved for use in breeding, pregnant, or lactating dogs.
Simparica® & Simparica Trio® Possible Side Effects
Permethrin is an insecticide used to kill fleas. It's safe to use on dogs, but is extremely poisonous for cats. Permethrin is found in a number of different flea products for dogs, including spot-on treatments, shampoos, sprays and flea collars. It's also a common ingredient in household flea sprays and powders.
Apply a concentrated IGR insecticidal spray.
These types of products are designed to kill the eggs and the “youngins” of fleas and other pest insects, for this matter. It is also said that the main IGR ingredient affects adult fleas, as well. They become infertile and their eggs don't hatch.
Both Simparica and Simparica Trio are effective preventative medications that can protect your dog from fleas and ticks. However, Simparica Trio offers additional heartworm protection while eliminating other internal parasites like hookworms and roundworms.
For use in dogs only. Do not use SIMPARICA in cats. SIMPARICA should not be used in dogs less than 6 months of age (see Animal Safety). Keep SIMPARICA in a secure location out of reach of dogs, cats and other animals to prevent accidental ingestion or overdose.
While Simparica Trio is generally effective in protecting dogs from fleas, no medication offers 100% protection at all times. Variations in individual response, incorrect administration, or a particularly heavy flea presence can reduce effectiveness.
Sarolaner (brand name Simparica®) is used to treat and control flea and tick infestations in dogs. The dog ingests sarolaner, and the drug is distributed throughout the dog's body. When fleas or ticks bite the dog, they are exposed to the drug and killed during their blood meal.
If you have a breeding dog, a pregnant dog, or a puppy between 6 and 8 weeks old, Heartgard Plus is the safest option. If you're hoping to find a broad-spectrum product that protects against fleas and ticks while it defends against internal parasites, Simparica Trio is the clear winner.
Popular, vet-recommended flea and tick medicines for dogs include chewables Simparica and Credelio, plus Bravecto topical, all of which are prescription medicines. Your vet can help you choose the best flea and tick medication for your individual dog based on their specific needs.