Do not use for more than a few days at a time unless your doctor tells you to. Do not take more than the recommended dose unless your doctor tells you to. Do not use PANADOL OSTEO to treat any other complaints unless your pharmacist or doctor tells you to.
Paracetamol can be taken when needed, that is when you feel the pain, or it may be taken regularly to manage persistent pain. Regular dosing is recommended to treat the persistent pain that may be associated with arthritis.
In general, acetaminophen (the active ingredient contained in Panadol Osteo) is well-tolerated when administered in therapeutic doses. The most commonly reported adverse reactions have included nausea, vomiting, constipation. Injection site pain and injection site reaction have been reported with the IV product.
Paracetamol overdose may cause liver failure which may require liver transplant or lead to death. Underlying liver disease increases the risk of paracetamol-related liver damage. Patients who have been diagnosed with liver or kidney impairment must seek medical advice before taking this medication.
Adult dosing of paracetamol
The recommended paracetamol dosing for adults and children 12 years and over is 500 to 1000mg every four to six hours as necessary, with a maximum of 4000mg in any 24 hour period.
Long-term paracetamol use could increase the risk of heart disease and strokes in people with high blood pressure, a study suggests.
Do not use for more than a few days at a time unless your doctor tells you to. Do not take more than the recommended dose unless your doctor tells you to. Do not use PANADOL OSTEO to treat any other complaints unless your pharmacist or doctor tells you to.
It can provide long-lasting relief from persistent pain. Panadol Osteo can be a convenient choice, containing a higher dose of paracetamol than regular Panadol tablets. With only 3 daily doses, each lasting up to 8 hours, Panadol Osteo may provide up to 24-hour relief from pain with just 3 doses.
This study clearly shows that paracetamol – the world's most used drug – increases blood pressure, one of the most important risk factors for heart attacks and strokes.
Panadol Osteo, however, is specifically designed to treat persistent pain associated with osteoarthritis, as well as muscular aches and pains. It contains a higher dosage of Panadol's active ingredient – paracetamol – with 665mg. Regular Panadol contains 500mg of paracetamol, by comparison.
The primary difference is that ibuprofen is a non-steroidal anti-inflammatory drug (NSAID), meaning that it treats inflammation. Paracetamol does not. For example, paracetamol can be taken to treat the pain of arthritis, but it will not treat the inflammation which is causing the pain.
Because ibuprofen has a strong anti-inflammatory effect, it is more effective than paracetamol at controlling certain types of pain, including rheumatoid arthritis, period pain, and muscular injuries.
NSAIDs are the most effective oral medicines for OA. They include ibuprofen (Motrin, Advil) naproxen (Aleve) and diclofenac (Voltaren, others). All work by blocking enzymes that cause pain and swelling.
Nonsteroidal anti-inflammatory drugs or NSAIDs. OTC doses of these drugs, including ibuprofen (Advil, Motrin IB) and naproxen sodium (Aleve), may be useful for relieving pain. At higher prescription doses they may also relieve inflammation.
Regular exercise. Regular exercise is one of the most effective treatments for managing osteoarthritis. It keeps your joints and muscles healthy and flexible and can reduce pain. Exercise helps prevent other health problems as well.
All MRP products, including market leader Panadol Osteo, now sit behind the pharmacy counter in order to promote the quality use of medicines for osteoarthritis (OA) sufferers. Packs labelled S2 will be able to be sold behind the counter until 31 May 2021.
Panadeine and Panadeine Forte:
Codeine is a narcotic analgesic which will provide stronger pain relief. The usual dose of Panadeine or Panadeine Forte is the same as Panadol, that is one to two tablets every four to six hours up to a maximum of eight tablets per day.
It's safe to take paracetamol regularly for many years, as long as you do not take more than the recommended dose.
Adults and children aged 12 years and over: Take 2 tablets swallowed whole three times a day, every six to eight hours as needed. Do not take more than 6 tablets in 24 hours. Swallow the tablets whole with a full glass of water.
Effective for the relief of persistent pain associated with osteoarthritis and muscular aches and pains such as backache. Provides effective temporary relief of pain and discomfort associated with: headache, tension headache, cold and flu, period pain, toothache and pain after dental procedures. Reduces fever.
Long-term use of paracetamol may also cause heart problems. The systematic review of eight observational studies showed that four found a heightened risk, ranging from 19 to 68 percent, of cardiovascular problems. Higher doses of paracetamol was also associated with heart attack and stroke, according to another study.
Paracetamol overdose is one of the leading causes of acute liver failure. Adults can usually take one or two 500mg tablets every 4-6 hours, but shouldn't take more than 4g (eight 500mg tablets) in the space of 24 hours.
Acute liver failure from paracetamol toxicity has a high mortality rate of 30% if there is no liver transplantation available[89,90]. Among intentional and accidental overdose, the liver transplant-free survival rate was not found to significantly differ.