So, on average, with the recommended starting Ozempic dose of 0.25 mg, a 500 to 1000 calorie reduced diet, and exercise 3 times a week, you can expect to lose 3-5 pounds in the first month of treatment, which works out to about 3% of body weight for most overweight or obese individuals.
Once you begin using Ozempic, some people can find it takes several weeks to see any weight loss, yet others may see some weight loss within a week or 2. While it can be difficult, try to remain patient — change looks different for everyone.
You may need to increase your physical activity
As mentioned above, Ozempic should be used in combination with a reduced-calorie diet and increased exercise. For those starting with Ozempic, health professionals may recommend beginning with 150 minutes per week of physical activity, such as walking.
On average, a user can lose about 3 to 5% of their body weight after using Ozempic for a month regularly. This equates to about 4 to 6 pounds on average. Using a higher potency of the drug may result in more weight loss, but it isn't recommended that you start taking it right away.
Ozempic is also used off-label for weight loss. In particular, it can help reduce the amount of belly fat. This is because Ozempic works by making you feel fuller for longer, which can help you resist overeating by controlling cravings and hunger.
Once you use Ozempic, you should experience increased satiety, which helps your body to gradually adjust and begin to lose weight. In general, most people lose a minimum of 5% of their starting weight when they use Ozempic.
Incorrect Calorie Intake
While Ozempic can help with weight loss, it is not a “magic pill”. It won't work if you are still intaking more calories than your body burns. Calorie intake plays a significant role in weight loss. A caloric deficit is necessary alongside Ozempic supplementation to reach your physique goals.
Ozempic® should be administered by a patient once weekly on the same day each week, at any time of the day, with or without meals. The day of weekly administration can be changed if necessary as long as the time between 2 doses is at least 2 days (>48 hours).
Although steady state levels are reached in 4 to 5 weeks, clinical effectiveness with Ozempic will vary from person to person and may take longer due to unique factors such as age, weight, amount of body fluid, additional medications you take, kidney or liver function, or your other medical conditions.
A study found that at the highest dose of Wegovy (2.4 mg), patients lost on average 15% of their total body weight after 1 year. In patients with diabetes, one study showed that taking Ozempic at the highest dose of 2 mg led to on average ~15 lbs (6.9 kg) weight loss after 40 weeks.
Study 2: Patients using the Ozempic 1 mg dose lost on average 12 lb (5.5 kg), and those using the 2 mg dose lost 14 lb (6.3 kg).
Ozempic can cause nausea and vomiting if taken after eating foods high in fat or sugar. It is recommended that you take Ozempic before meals, rather than after, to minimise any potential side effects from eating high-fat or high-sugar foods.
A 2022 study found that most individuals gain weight back a year after stopping the medication.
Weight loss—whether through medication or diet—may lead to a loss of muscle mass, which can be especially concerning for older adults. While muscle mass declines naturally with age, shedding a lot of weight in a short time with drugs like Ozempic or Wegovy can lead to reduced strength and bone density.
It is important to have your blood sugar levels checked regularly. This is the only way to know if Ozempic is working properly for you. Your doctor will recommend how frequently you should do this. Store unused Ozempic pens in the fridge at 36°F to 46°F (2°C to 8°C).
Can I enjoy a drink while on Ozempic medication? The short answer is yes: You can drink alcohol while taking Ozempic.
The good news is, there are no foods that you have to eat or have to avoid while taking Ozempic. Still, Ozempic and other GLP-1 medications will be most effective for weight loss and blood sugar control when combined with a healthy diet and regular exercise.
Based on the results of our weight management program, our patients have lost an average of 7.7 pounds in only 4 weeks on the lowest, introductory dose of semaglutide!
Nausea and Vomiting
One of the most common side effects of Ozempic is gastrointestinal symptoms such as nausea, vomiting, diarrhoea and constipation. The reason behind these unpleasant symptoms is that Ozempic slows down the movement of food through your stomach and intestines.
Ozempic and its sister medication, Wegovy — approved for weight loss for people who are obese or overweight with weight-related medical conditions — are considered long-term or lifelong treatments.