It can take months for the immune system to rebound after chemo and radiation. The specific drug(s) can make a difference in recovery time.
Radiation is most often given to just one part of the body, so the whole immune system isn't damaged by it. Still, depending on the dose and the part of the body being treated with radiation, the skin or mucous membranes may be damaged, so you're less able to keep germs out.
Radiation therapy can potentially affect your immune system, especially if a significant amount of bone marrow is being irradiated because of its role in creating white blood cells. However, this doesn't typically suppress the immune system enough to make you more susceptible to infections.
Most side effects generally go away within a few weeks to 2 months of finishing treatment. But some side effects may continue after treatment is over because it takes time for healthy cells to recover from the effects of radiation therapy. Late side effects can happen months or years after treatment.
The general effects of radiation therapy like fatigue, nausea, and headaches resolve fairly quickly after treatment. Your body just needs time to process the radiation but can recover within a few weeks. Delayed side effects of radiation therapy, on the other hand, may require further treatment to alleviate.
Now, new research suggests that the effects of chemotherapy can compromise part of the immune system for up to nine months after treatment, leaving patients vulnerable to infections – at least when it comes to early-stage breast cancer patients who've been treated with a certain type of chemotherapy.
After radiation therapy begins, fatigue usually increases until mid-way through the course of treatments and then stays about the same until treatment ends. For many patients, fatigue improves after radiation therapy stops. However, in some patients, fatigue will last months or years after treatment ends.
Some sources of the radiation stay in the body for only a short time. Others, like seeds and radioactive medicines stay in the body forever. But the radiation gets weaker and is used up over time. Internal radiation does make you radioactive for a short time.
Some cancers are difficult to treat and have high rates of recurrence. Glioblastoma, for example, recurs in nearly all patients, despite treatment. The rate of recurrence among patients with ovarian cancer is also high at 85%.
Feeling very tired and lacking energy (fatigue) for day-to-day activities is the most common side effect of radiation therapy to any area of the body. During treatment, your body uses a lot of energy dealing with the effects of radiation on normal cells.
Antioxidants include vitamins A, C, E, beta-carotene, and selenium, among others. Many people take antioxidants during treatment hoping they can protect normal tissues from treatment side effects. Some feel this may improve tumor response to treatment and improve survival.
Wound healing after radiation therapy doesn't have many alternatives beyond HBOT. You can try to relieve your symptoms using topical creams, NSAIDs, or surgery, but hyperbaric oxygen therapy is the only treatment available to stimulate the internal healing needed to overcome the effects of radiation.
Fatigue is the most common acute side effect of radiation therapy. It is believed to be caused by the large amount of energy that is used by the body to heal itself in response to radiation therapy. Most people begin to feel fatigued about 2 weeks after radiation treatments begin.
For most people, the cancer experience doesn't end on the last day of radiation therapy. Radiation therapy usually does not have an immediate effect, and it could take days, weeks or months to see any change in the cancer. The cancer cells may keep dying for weeks or months after the end of treatment.
The tiredness often reaches its maximum 1 to 2 weeks after the end of treatment. A small number of people are asleep for a lot of the day after a long course of radiotherapy to the brain. This called somnolence syndrome.
Radiotherapy can cause tiredness because the body is using up your energy reserves to repair healthy cells damaged by the radiotherapy. If you are taking steroids, you might also find that you feel extremely tired when you stop taking them. Travelling to the hospital each day for treatment can also make you tired.
The side effects of radiotherapy usually peak up to two weeks after treatment has finished. The effects of radiotherapy continue developing, and it may take a further couple of weeks to several months for you to feel normal, depending on the area of the body that has been treated.
Cancer survival rates by cancer type
The cancers with the lowest five-year survival estimates are mesothelioma (7.2%), pancreatic cancer (7.3%) and brain cancer (12.8%). The highest five-year survival estimates are seen in patients with testicular cancer (97%), melanoma of skin (92.3%) and prostate cancer (88%).
A second round of radiation treatment can increase the risk of a second cancer. The body doesn't forget its first encounter with radiation, so you can't treat it a second time like you did the first time.
Don't wear tight clothing over the treatment area. It's important not to rub, scrub or scratch any sensitive spots. Also avoid putting anything that is very hot or very cold—such as heating pads or ice packs—on your treated skin.