A group of blood tests called liver function tests can be used to diagnose liver disease. Other blood tests can be done to look for specific liver problems or genetic conditions. Imaging tests. An ultrasound, CT scan and MRI can show liver damage.
Acute liver failure can develop quickly in an otherwise healthy person, and it is life-threatening. If you or someone you know suddenly develops a yellowing of the eyes or skin; tenderness in the upper abdomen; or any unusual changes in mental state, personality or behavior, seek medical attention right away.
Liver function tests (also known as a liver panel) are blood tests that measure different enzymes, proteins, and other substances made by the liver. These tests check the overall health of your liver.
Blood tests
A low level of serum albumin suggests your liver is not functioning properly. A blood test may also look for signs of abnormal blood clotting, which can indicate significant liver damage.
As the liver becomes more severely damaged, more obvious and serious symptoms can develop, such as: yellowing of the skin or whites of the eyes (jaundice) swelling in the legs, ankles and feet caused by a build-up of fluid (oedema) swelling in your abdomen caused by a build-up of fluid known as ascites.
Nausea and upset stomach are common early symptoms of liver disease, but as your liver's ability to eliminate toxins decreases, your digestive distress will likely increase. Ongoing nausea is a reaction to excess waste products in the body, and unexplained vomiting is often linked to liver problems.
The liver is very resilient and capable of regenerating itself. Each time your liver filters alcohol, some of the liver cells die. The liver can develop new cells, but prolonged alcohol misuse (drinking too much) over many years can reduce its ability to regenerate.
Stage 1 is inflammation of your liver, caused by your immune system reacting to a foreign substance, like toxins. Chronic inflammation can lead to an enlarged liver. Inflammation can result from fatty liver, hepatitis, and other causes. Stage 2 is liver fibrosis or liver scarring, caused by chronic inflammation.
Liver failure can develop slowly or rapidly, depending on the cause and the condition of the liver. Chronic liver failure: The most common type of liver failure is chronic, which can take months or years to develop.
Your liver can keep working even if part of it is damaged or removed. But if it starts to shut down completely—a condition known as liver failure—you can survive for only a day or 2 unless you get emergency treatment. Many things can affect liver function.
Feeling sluggish, tired and fatigued constantly. White or yellow-coated tongue and/or bad breath. Weight gain – especially around the abdomen. Cravings and/or blood sugar issues.
Most people with liver disease report abdominal pain. Pain in your liver itself can feel like a dull throbbing pain or a stabbing sensation in your right upper abdomen just under your ribs.
You likely won't notice an enlarged liver on your own. In some severe cases, you might notice a feeling of bloating or fullness in your belly, or an ache in your upper right abdomen, where your liver is. It's more likely your healthcare provider will discover it during an exam.
The liver is very resilient and capable of regenerating itself. Each time your liver filters alcohol, some of the liver cells die. The liver can develop new cells, but prolonged alcohol misuse (drinking too much) over many years can reduce its ability to regenerate.
Some liver problems can be treated with lifestyle modifications, such as stopping alcohol use or losing weight, typically as part of a medical program that includes careful monitoring of liver function. Other liver problems may be treated with medications or may require surgery.
Elevated levels of bilirubin (jaundice) might indicate liver damage or disease or certain types of anemia. Gamma-glutamyltransferase (GGT). GGT is an enzyme in the blood. Higher-than-normal levels may indicate liver or bile duct damage.
Gamma-glutamyl transpeptidase test: This test measures the level of gamma-glutamyl transpeptidase (an enzyme that is produced in the liver, pancreas, and biliary tract). This test is often performed to assess liver function, to provide information about liver diseases, and to detect alcohol ingestion.