Saxenda does not directly "melt" fat. Instead, it supports weight loss primarily by regulating appetite and reducing calorie intake, which leads to the body burning stored fat for energy over time when used in conjunction with a reduced-calorie diet and increased physical activity.
It is important to understand that Saxenda does not burn fat directly. The main benefit comes from helping people eat less in a sustainable way.
The Best Weight Loss Injections
Saxenda (liraglutide) works by mimicking GLP-1, a naturally occurring hormone that regulates appetite and blood sugar. Whilst it does not directly alter sex hormones like oestrogen or testosterone, it does influence metabolic hormones and can indirectly affect hormonal balance through weight loss.
Saxenda® should be used with a reduced-calorie diet and increased physical activity. Click here for full Indications and Usage.
Ozempic tends to result in more weight loss than Saxenda, and it's more cost-effective per pound lost. However, it's a once-weekly injection, while Saxenda requires daily dosing, which may affect user preference.
Kelly Clarkson uses a prescription weight-loss medication, but specified it's not Ozempic, though she hasn't revealed the exact drug; it helps her body break down sugar, a necessity due to pre-diabetes, alongside healthy habits like a high-protein diet, increased walking, and a better lifestyle after moving to New York. Her doctor encouraged medication due to concerning blood work, leading her to start after a health scare prompted change, though she initially hesitated due to thyroid issues.
Nausea is the most common side effect when first starting Saxenda®. If you (or your teen) experience nausea, speak with your respective health care providers about ways to manage it. They may suggest some of the following: Eat bland, low-fat foods, like crackers, toast, and rice.
Saxenda UK Dose
The Saxenda starting dose is 0.6 mg subcutaneously, SC, per day for 1 week. You should increase the dose by 0.6 mg each week until the full maintenance dose of 3 mg is reached. By the start of the fifth week you should be on the maximum maintenance dose.
People have been filing Saxenda lawsuits after experiencing serious adverse effects in connection with the drug. The lawsuits allege that Novo Nordisk, the manufacturer of Saxenda and similar drugs, failed to warn of the potential for stomach paralysis and other conditions resulting from Saxenda use.
Adele's significant weight loss wasn't from a quick fix but a two-year journey combining intense, varied workouts (strength training, Pilates, boxing, hiking, cardio) and lifestyle changes, driven largely by addressing anxiety and improving her mental health, though she also worked with trainers and focused on eating more whole foods while denying specific restrictive diets like intermittent fasting. She described getting "addicted" to exercise, often training multiple times daily, emphasizing getting stronger, not just losing weight.
Physical activity helps burn abdominal fat. One of the biggest benefits of exercise is that you get a lot of bang for your buck on body composition.
For most people, this occurs after 4-8 weeks. Clinical trials have shown that people who use Saxenda alongside a healthy lifestyle can lose, on average, 5% of their body weight in 8 weeks, 7% in 16 weeks, 8% in 24-36 weeks, and 9% in 56 weeks.
No energy on Saxenda is a commonly reported concern among patients using this GLP-1 receptor agonist for weight management. Liraglutide 3.0 mg (Saxenda) works by reducing appetite and slowing gastric emptying, which can lead to significant caloric restriction and subsequent fatigue.
Liraglutide (Victoza, Saxenda) can interact with insulin, sulfonylureas, and glinides. It can also interact with oral medications and those that raise blood glucose (sugar) levels, such as prednisone and metoprolol. These interactions can usually be managed with dosage adjustments and blood sugar monitoring.
However, studies have also shown that Ozempic leads to fewer side effects and adverse events than Saxenda, with people tolerating Ozempic better.
Common Reasons Saxenda Makes You Feel Hungry
Insufficient dose escalation is a frequent cause; Saxenda requires gradual titration from 0.6 mg daily up to the maintenance dose of 3.0 mg daily over five weeks. Patients who remain on lower doses may not achieve adequate GLP-1 receptor activation for appetite suppression.
You can use Saxenda® at any time of day, with or without food and drinks. It is preferable to use Saxenda® at about the same time each day, at a time that is most convenient for you. Only continue using Saxenda® if you have lost at least 5% of your initial body weight after 12 weeks on the 3.0 mg/day dose.
Saxenda may cause your heart rate to increase. Call your healthcare provider right away if you feel like your heart is pounding or racing when you are not exerting yourself. Liver Damage. Liver damage, also called hepatotoxicity, can happen when taking Saxenda.
Drink enough water to avoid dehydration
When starting Saxenda, it can cause nausea (feeling sick), vomiting (being sick) and diarrhoea (runny poo) that can last for a few days. This increases your risk of dehydration, which can cause serious kidney problems. Be sure to drink plenty of water or non-sugary beverages.
National Institute for Health and Care Excellence (NICE) recommends tirzepatide (Mounjaro®) for the management of obesity for certain patients. Tirzepatide (also called Mounjaro®) is a weight loss medicine that makes you feel fuller for longer and therefore less hungry.
She followed a low-carb diet, high in lean proteins and healthy fats, and eliminated processed foods from her meals. This helped in reducing her calorie intake while maintaining her energy levels for her workouts.
Kim Kardashian never confirmed Ozempic, but her ultra-slim frame in 2024 and 2025 kept rumors alive, especially after extreme dieting stories like crashing for the Met Gala dress.
The 30-30-30 rule for weight loss is a simple morning routine: eat 30 grams of protein within 30 minutes of waking, then do 30 minutes of low-intensity cardio (like a brisk walk) to help with fat loss and appetite control, according to this article from Moshy. Popularized by Tim Ferriss and wellness podcaster Gary Brecka, this method aims to kickstart your metabolism, increase fullness, and burn fat by leveraging your body's depleted glycogen stores after sleep, but it's not a magic bullet and works best as part of a balanced lifestyle, note Healthline and this article from bodyandsoul.com.au.