Many people with
Individuals with Marfan syndrome may have several distinct facial features including a long, narrow skull (dolichocephaly), deep-set eyes (enophthalmos), an abnormally small jaw (micrognathia) that may be recessed farther back than normal (retrognathia), abnormally flat cheek bones (malar hypoplasia), and an abnormal ...
Marfan syndrome can damage the blood vessels, heart, eyes, skin, lungs, and the bones of the hips, spine, feet, and rib cage. Some complications of Marfan syndrome can be treated or prevented, including heart disease, bone deformities such as a curved spine, eye conditions, crooked teeth, and collapsed lungs.
Marfan syndrome is an inherited disorder that affects connective tissue — the fibers that support and anchor your organs and other structures in your body. Marfan syndrome most commonly affects the heart, eyes, blood vessels and skeleton.
Marfan syndrome can be mild to severe, and may become worse with age, depending on which area is affected and to what degree. In Marfan syndrome, the heart is often affected. The aorta, the major artery of the body, may be more dilated (widened) than average.
Marfan syndrome can affect the bones and joints. For example, the breastbone can stick out or in. The spine may curve (called scoliosis), or swelling may occur around the spinal column. Many people with Marfan syndrome report foot pain and back pain.
Many people with Marfan syndrome have difficulty gaining weight, especially when they are younger, no matter how much they eat and how many protein shakes they consume. Some do find that they do put on weight, particularly around their middle, when they get older.
Symptoms of Marfan syndrome include: Fatigue. Dizzy spells. Shortness of breath.
Abraham Lincoln is the most famous American who had Marfan syndrome. So did Julius Caesar and Tutankhamen. In more recent times, Olympic swimmer Michael Phelps, basketball prospect Isaiah Austin and, perhaps, al-Qaeda leader Osama bin Laden had Marfan syndrome.
Marfan syndrome can be difficult to diagnose because the signs and symptoms can vary from person to person. In most cases, a diagnosis will be based on a thorough physical examination and a detailed assessment of a person's medical and family history.
Marfan syndrome is present at birth. However, you may not be diagnosed until you're a teen or young adult.
Cardiovascular complications develop throughout life, particularly aortic pathology, the major cause of death in MFS.
Marfan's Syndrome has an effect on the oral cavity, particularly in periodontal disease, as periodontal ligament appears to be a soft, cellular and richly vascular connective tissue, located between the cement and the alveolar bone.
Many people with Marfan syndrome will need glasses because they will develop myopia (nearsightedness) or have astigmatism (abnormal curvature of the eye). Patients with Marfan syndrome may also have a higher chance of developing cataracts, glaucoma, strabismus and retinal detachment.
The two primary features of Marfan syndrome are vision problems caused by a dislocated lens (ectopia lentis ) in one or both eyes and defects in the large blood vessel that distributes blood from the heart to the rest of the body (the aorta ).
For people with Marfan syndrome active sports such as track, basketball, baseball, volleyball, football, and strenuous activities such as heavy lifting should be avoided because they cause additional heart strain.
In addition, some MFS patients also have psychiatric symptoms such as depression and anxiety. As with many genetic disorders, patients with MFS also have concerns with various aspects of life, such as family planning and finances related to health care.
A high prevalence of sleep disordered breathing (SDB) has been reported in persons with Marfan syndrome (MFS), a single gene disorder of connective tissue resulting in premature death from aortic rupture.
In general, most people living with Marfan syndrome should exercise regularly through low-intensity (aerobic), low-impact activities adapted to meet their specific needs. Nearly every activity can be done at different intensity levels, and no recommendation holds true in all circumstances.
The most common type of benefit to apply if you have Marfan's Syndrome is Social Security Disability Insurance (SSDI) benefits. This is a benefit that pays you a portion of your monthly income to replace your earnings, because you are unable to work due to your illness.
Some people are only mildly affected by Marfan syndrome, while others develop more serious symptoms. Typical characteristics of Marfan syndrome include: being tall. abnormally long and slender limbs, fingers and toes (arachnodactyly) heart defects.
Differences in the bones and joints are some of the more obvious signs of Marfan syndrome. Weakened connective tissue can cause bones to grow longer than normal. It also affects ligament tissue, making it loose and more flexible.
However, with focused and appropriate medical and surgical intervention, patients with Marfan syndrome who have cardiovascular abnormalities can expect to live long and rewarding lives, similar to people without connective tissue disorders.
One of the most common inherited disorders affecting connective tissue, Marfan syndrome (MFS) is an autosomal dominant condition with a reported incidence of 1 in 3000 to 5000 individuals.