Although animals are infected worldwide brucellosis is well controlled in most developed countries including Australia. Rarely, brucellosis infections occur in humans.
Brucellosis is found globally and is a reportable disease in most countries.
People with brucellosis may develop fever, sweats, headaches, back pains, and physical weakness. In severe cases, the central nervous system and the lining of the heart may be affected. One form of the illness may also cause long-lasting symptoms, including recurrent fevers, joint pain, and fatigue.
Efforts at eradicating Brucellosis have been successful in the United States, but the battle continues in some regions. In 1956, there were 124,000 affected herds in the United States. Today, the disease is virtually eliminated in domestic livestock.
Brucellosis affects males and females in equal numbers. The disorder is rare in the United States since pasteurization of milk is routine and cattle are vaccinated against this disease. Fewer than 100 new cases are reported each year in the United States.
Inflammation of the inner lining of the heart chambers (endocarditis). This is one of the most serious complications of brucellosis. Untreated endocarditis can damage or destroy the heart valves and is the leading cause of brucellosis-related deaths.
Live-Attenuated Vaccines. In recent decades, the most effective way to control brucellosis has been to vaccinate animals. Although vaccination of individuals living in brucellosis endemic areas, veterinarians, livestock, and laboratory personnel is essential, human vaccines have not yet been developed (9).
Brucellosis is an infectious disease caused by bacteria. People can get the disease when they are in contact with infected animals or animal products contaminated with the bacteria. Animals that are most commonly infected include sheep, cattle, goats, pigs, and dogs, among others.
Lethality: Brucellosis has a very low mortality rate, less than 5% of untreated cases, with most deaths caused by endocarditis or meningitis.
Brucellosis is a zoonotic disease that severely hinders livestock productivity and human health worldwide. The burden that the disease places specifically on low-income countries has led the World Health Organization (WHO) to classify it as one of the world's leading 'neglected zoonotic diseases' [1].
Consumption of raw milk containing Brucella can cause brucellosis. Most cases of brucellosis associated with raw milk are caused by a strain called Brucella melitensis or Brucella abortus in people who traveled to countries where these strains are common and drank contaminated cow, sheep or goat milk.
Brucellosis can spread from dogs to people through contact with an infected dog's birthing fluids and vaginal discharge while birthing puppies. This is why dog breeders and veterinarians are at higher risk.
Humans can also contract the disease when slaughtering infected animals or when processing contaminated organs from freshly-killed, brucellosis infected livestock, wildlife or feral swine.
It is not found in Australia but occurs in many overseas countries, particularly in the Mediterranean, Middle East, Central Asia and Central America. Brucella abortus usually infects cattle. Bovine brucellosis (brucellosis in cattle) has been eradicated from all states of Australia, including NSW, since 1989.
Although brucellosis can be found worldwide, it is more common in countries that do not have effective public health and domestic animal health programs. Areas currently listed as high risk are: the Mediterranean Basin (Portugal, Spain, Southern France, Italy, Greece, Turkey, North Africa)
Overall, three (9.38%) patients had known risk factors for tuberculosis, while six (18.75%) had risk factors for brucellosis. Conclusions: There is a clear overlap between brucellosis and tuberculosis both in terms of clinical presentation and laboratory parameters.
Brucellosis is an infectious disease caused by Brucella species. It is known by many other names, including remitting fever, undulant fever, Mediterranean fever, Maltese fever, Gibraltar fever, Crimean fever, goat fever, and Bang disease.
For simple infections, doxycycline (100 mg PO twice daily for 6 weeks) may be the most appropriate monotherapy; however, relapse rates with such monotherapy approach 40% and as a result, rifampin (600-900 mg/day) is usually added.
Depending on the timing of treatment and severity of illness, recovery may take a few weeks to several months. Death from brucellosis is rare, occurring in no more than 2% of all cases. Generally, the antibiotics doxycycline and rifampin are recommended in combination for a minimum of 6-8 weeks.
Brucellosis can be diagnosed in a laboratory by finding bacteria in samples of blood, bone marrow or other bodily fluids. Serological tests can also be done to detect antibodies against the bacteria. Learn more about what can be done to help confirm diagnosis of this disease.
It was later named for British army physician David Bruce, who in 1887 first isolated and identified the causative bacteria, Brucella, from the spleen of a soldier who had died from the infection.
Disinfectants with bleach, at least 70 percent ethanol, iodine/alcohol solutions, glutaraldehyde or formaldehyde will effectively kill the bacteria.
Person-to-person spread of brucellosis is extremely rare. Infected mothers who are breast-feeding may transmit the infection to their infants. Sexual transmission has been rarely reported. While uncommon, transmission may also occur via tissue transplantation or blood transfusions.
Symptoms and Signs of Brucellosis
Onset may be sudden, with chills and fever, severe headache, joint and low back pain, malaise, and occasionally diarrhea. Or onset may be insidious, with mild prodromal malaise, muscle pain, headache, and pain in the back of the neck, followed by a rise in evening temperature.