It has also been shown in clinical trials by its pharmaceutical manufacturer to be more effective for weight loss compared to other GLP-1 medications. Although many lost weight, some people did gain weight in the trials.
Studies have similarly shown weight rebound in people who stop taking Ozempic. She said it's tied to how the drugs work. They mimic a hormone produced in the gut called GLP-1, which signals to the brain when a person is full.
Semaglutide (Ozempic, Wegovy, Rybelsus) can cause side effects that some people are unable to tolerate. Following dosing guidelines can help manage these side effects. Nausea, vomiting, and diarrhea are the most common semaglutide side effects.
You Will Regain Weight
Because people stop feeling full and their food cravings return when they stop Ozempic, weight gain is likely, Kushner says.
You've hit a plateau
It's normal to eventually hit a point where your weight loss slows down, especially if you're not working on keeping or building up your muscle mass. Losing muscle along with fat slows your metabolism and can slow down your weight loss.
Common Side Effects of Ozempic
“The most common side effects are gastrointestinal in nature: nausea, vomiting, diarrhea and constipation.” While the majority of people who take Ozempic will most likely experience these symptoms at some point during their treatment, they should subside over time, continues Dr. McGowan.
How Long Can You Stay on Ozempic (semaglutide)? A person can stay on Ozempic® so long as they are tolerating the medication and it is deemed appropriate by their treating provider. There is no specific time frame when someone should stop taking Ozempic as it is a medication that is intended for chronic (long-term) use.
Ozempic can cause nausea and vomiting if taken after eating foods high in fat or sugar. It is recommended that you take Ozempic before meals, rather than after, to minimise any potential side effects from eating high-fat or high-sugar foods.
Will Ozempic or Wegovy reduce belly fat? The answer appears to be yes. That Novo Nordisk-funded study of almost 2,000 overweight or obese adults without diabetes also found their visceral fat — the type that accumulates in the belly — was reduced from baseline with semaglutide, along with their total fat mass.
No specific foods need to be avoided while taking Ozempic and there is no fixed Ozempic diet or meal plans — one less thing for you to worry about! For certain people, carbohydrates, sugary, high-fat, heavily processed and calorie-dense foods are off-limits when dieting.
“Ozempic face” is a term for common side effects of the type 2 diabetes medication semaglutide (Ozempic). It can cause sagging and aging of facial skin. A doctor may recommend lifestyle modifications or facial fillers to treat these effects.
The active ingredient in Ozempic is semaglutide, which works by inducing satiety. This feeling of being satisfied or “full”, suppresses appetite. This is why it works for weight loss. Semaglutide also helps the pancreas produce insulin, which is how it helps manage type 2 diabetes.
Teresa Shepherd said she lost 90 pounds while taking an off-brand version of the drug Ozempic for around eight months. Shepherd, who lives in Florida, told "Good Morning America" she has been able to maintain her weight loss two months after stopping the medication.
Ozempic works by stimulating the pancreas to release insulin, and also stops your liver from producing glucagon. This increases your insulin sensitivity while reducing your insulin resistance. It also slows down digestion and gastric emptying, helping you to feel fuller for longer.
Research has proven that higher doses of Ozempic — 2.4 milligrams of semaglutide — are very effective for reducing weight in people with obesity. In one landmark study, people with obesity who used the drug in combination with lifestyle interventions lost about 15% percent of their body weight in 68 weeks.
Can I drink alcohol while using Ozempic? The short answer is yes: you can drink alcohol while taking Ozempic. In the U.S., where Ozempic is created and distributed from, the Food and Drug Administration has not provided any specific disclaimers on mixing Ozempic and alcohol .
The starting Ozempic dosage is usually 0.25 mg once weekly. This dose isn't intended to have an effect on your blood glucose. Instead, it's meant to help your body start adjusting to digestion-related side effects.
A study found that at the highest dose of Wegovy (2.4 mg), patients lost on average 15% of their total body weight after 1 year. In patients with diabetes, one study showed that taking Ozempic at the highest dose of 2 mg led to on average ~15 lbs (6.9 kg) weight loss after 40 weeks.
What is the best time to take Ozempic®? Administer Ozempic® once weekly on the same day each week, at any time of the day, with or without meals.
You Might Be Eating Too Little
This phenomenon is called “starvation mode,” and while your body isn't actually starving, it will naturally hold onto whatever calories it receives in an effort to help you maintain your energy balance.